ID D7UW16_LISGR Unreviewed; 898 AA.
AC D7UW16;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=Glycosyl hydrolase family 38 N-terminal domain protein {ECO:0000313|EMBL:EFI83970.1};
DE EC=3.2.1.24 {ECO:0000313|EMBL:EFI83970.1};
GN ORFNames=HMPREF0556_10523 {ECO:0000313|EMBL:EFI83970.1};
OS Listeria grayi DSM 20601.
OC Bacteria; Bacillota; Bacilli; Bacillales; Listeriaceae; Listeria.
OX NCBI_TaxID=525367 {ECO:0000313|EMBL:EFI83970.1, ECO:0000313|Proteomes:UP000010119};
RN [1] {ECO:0000313|EMBL:EFI83970.1, ECO:0000313|Proteomes:UP000010119}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 20601 {ECO:0000313|EMBL:EFI83970.1,
RC ECO:0000313|Proteomes:UP000010119};
RA Muzny D., Qin X., Buhay C., Dugan-Rocha S., Ding Y., Chen G., Hawes A.,
RA Holder M., Jhangiani S., Johnson A., Khan Z., Li Z., Liu W., Liu X.,
RA Perez L., Shen H., Wang Q., Watt J., Xi L., Xin Y., Zhou J., Deng J.,
RA Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L., Villasana D., Johnson A.,
RA Liu J., Liyanage D., Lorensuhewa L., Robinson T., Song A., Song B.-B.,
RA Dinh H., Thornton R., Coyle M., Francisco L., Jackson L., Javaid M.,
RA Korchina V., Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N.,
RA Okwuonu G., Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W.,
RA Jakkamsetti A., Pham P., Ruth R., San Lucas F., Warren J., Zhang J.,
RA Zhao Z., Zhou C., Zhu D., Lee S., Bess C., Blankenburg K., Forbes L.,
RA Fu Q., Gubbala S., Hirani K., Jayaseelan J.C., Lara F., Munidasa M.,
RA Palculict T., Patil S., Pu L.-L., Saada N., Tang L., Weissenberger G.,
RA Zhu Y., Hemphill L., Shang Y., Youmans B., Ayvaz T., Ross M.,
RA Santibanez J., Aqrawi P., Gross S., Joshi V., Fowler G., Nazareth L.,
RA Reid J., Worley K., Petrosino J., Highlander S., Gibbs R.;
RL Submitted (JUN-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 38 family.
CC {ECO:0000256|ARBA:ARBA00009792}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFI83970.1}.
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DR EMBL; ACCR02000003; EFI83970.1; -; Genomic_DNA.
DR RefSeq; WP_003757295.1; NZ_GL538353.1.
DR AlphaFoldDB; D7UW16; -.
DR STRING; 525367.HMPREF0556_10523; -.
DR eggNOG; COG0383; Bacteria.
DR HOGENOM; CLU_003442_2_1_9; -.
DR Proteomes; UP000010119; Unassembled WGS sequence.
DR GO; GO:0004559; F:alpha-mannosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006013; P:mannose metabolic process; IEA:InterPro.
DR CDD; cd10814; GH38N_AMII_SpGH38_like; 1.
DR Gene3D; 2.60.40.2210; -; 1.
DR Gene3D; 2.60.40.2220; -; 1.
DR Gene3D; 3.20.110.10; Glycoside hydrolase 38, N terminal domain; 1.
DR Gene3D; 1.20.1270.50; Glycoside hydrolase family 38, central domain; 1.
DR InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR InterPro; IPR041509; GH38_beta-1.
DR InterPro; IPR041147; GH38_C.
DR InterPro; IPR011330; Glyco_hydro/deAcase_b/a-brl.
DR InterPro; IPR011682; Glyco_hydro_38_C.
DR InterPro; IPR015341; Glyco_hydro_38_cen.
DR InterPro; IPR037094; Glyco_hydro_38_cen_sf.
DR InterPro; IPR000602; Glyco_hydro_38_N.
DR InterPro; IPR027291; Glyco_hydro_38_N_sf.
DR InterPro; IPR028995; Glyco_hydro_57/38_cen_sf.
DR PANTHER; PTHR46017; ALPHA-MANNOSIDASE 2C1; 1.
DR PANTHER; PTHR46017:SF2; MANNOSYLGLYCERATE HYDROLASE; 1.
DR Pfam; PF09261; Alpha-mann_mid; 1.
DR Pfam; PF17677; Glyco_hydro38C2; 1.
DR Pfam; PF18438; Glyco_hydro_38; 1.
DR Pfam; PF07748; Glyco_hydro_38C; 1.
DR Pfam; PF01074; Glyco_hydro_38N; 1.
DR SMART; SM00872; Alpha-mann_mid; 1.
DR SUPFAM; SSF88688; Families 57/38 glycoside transferase middle domain; 1.
DR SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR SUPFAM; SSF88713; Glycoside hydrolase/deacetylase; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000313|EMBL:EFI83970.1};
KW Hydrolase {ECO:0000313|EMBL:EFI83970.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000010119}.
FT DOMAIN 297..370
FT /note="Glycoside hydrolase family 38 central"
FT /evidence="ECO:0000259|SMART:SM00872"
SQ SEQUENCE 898 AA; 101707 MW; 1FDCCE2ED8149475 CRC64;
MKEVVHVISH SHWDREWYLP YEKHHMRLIE LIDDLLELFQ KDPAFRYFHL DGQTIILEDY
LEVRPEKEQE LRQAVQAGKL KIGPFYILQD ALLTSSESNV RNMLVGMETV KKWGVDPVSV
GYFPDTFGNM GQAAQILQQG GIDVAAFGRG VKPTGFNNVV INDDKYTSPF SEMWWQGPDG
SKVLGLLFAN WYSNGNEIPS EREAARAFWD EKLADAKRYA STNQLLMMNG CDHQPVQKDL
SAAIQLANEL YPEIEFVHSN FDDYLKAVRA ELPADLNQVE GELTSQESDG WYTLANTASA
RIYLKQANTK VSRLLENIAE PLSVMAGEAG KAYPHDPLRY AWKKLMQNHP HDSICGCSVD
EVHRTMVERF AEAEEVADYI ATEAADYLAA KVDTSAFPAD AKPFVVWNTA GARKTGSVIV
EIEWERILFA GHDHETLYDK LEKKGIPTIC VQDTHGETVA FDLVGSEVRF GYDLPKDGFR
VPYMARYVKV ALFLEEMPAF SWRTYALVQS AEAAEIENLV SAEPRLMEND YLRVQVGEDG
TVAVFDKQTG TNYEDVLYYE ETGDIGNEYI FFEPADSKRI YSKDGDTAVT MLSNTANVAE
IEIVSTMMVP HSADDTLARE QKAIKEFRRR EAKRSVEMVP FVIHTTLRLE KYNRQLQVFS
AFDNQVKDHR LRAIIQTDIH TEQHQADSIF ETVTRPNRPA TVWENPTNPQ HQHQFVHLAD
ESKGITVSNY GLNEYEILNE AKPKIALTLL RSVGELGDWG YFPTPEAQCL GAQQVAFAIE
FHQAGEETAT YQRAKNFQIP FTFSQTSIHT GTQSPEHHFL EVEGDAFSVT ALKYKEASSD
LLLRGYNLTE RIADLRVRFA GKQLYRSNLL EEKTGAFEGQ IKGAEIVTLG FENTNHIG
//
