ID   D8FGJ2_9FIRM            Unreviewed;      1425 AA.
AC   D8FGJ2;
DT   05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2010, sequence version 1.
DT   27-MAR-2024, entry version 33.
DE   SubName: Full=Putative CoA-substrate-specific enzyme activase {ECO:0000313|EMBL:EFK39809.1};
GN   ORFNames=HMPREF9131_1476 {ECO:0000313|EMBL:EFK39809.1};
OS   Peptoniphilus sp. oral taxon 836 str. F0141.
OC   Bacteria; Bacillota; Tissierellia; Tissierellales; Peptoniphilaceae;
OC   Peptoniphilus.
OX   NCBI_TaxID=768724 {ECO:0000313|EMBL:EFK39809.1, ECO:0000313|Proteomes:UP000004869};
RN   [1] {ECO:0000313|EMBL:EFK39809.1, ECO:0000313|Proteomes:UP000004869}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=F0141 {ECO:0000313|EMBL:EFK39809.1,
RC   ECO:0000313|Proteomes:UP000004869};
RA   Durkin A.S., Madupu R., Torralba M., Methe B., Sutton G., Nelson K.E.;
RT   "Genome Sequence of Peptoniphilus sp. oral taxon 836 str. F0141.";
RL   Submitted (JUN-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC         Evidence={ECO:0000256|ARBA:ARBA00001966};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EFK39809.1}.
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DR   EMBL; AEAA01000004; EFK39809.1; -; Genomic_DNA.
DR   RefSeq; WP_009344694.1; NZ_AEAA01000004.1.
DR   Proteomes; UP000004869; Unassembled WGS sequence.
DR   GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.420.40; -; 4.
DR   InterPro; IPR002731; ATPase_BadF.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR018709; CoA_activase_DUF2229.
DR   InterPro; IPR008275; CoA_E_activase_dom.
DR   NCBIfam; TIGR00241; CoA_E_activ; 1.
DR   PANTHER; PTHR32329:SF4; ACTIVATOR OF 2-HYDROXYACYL-COA DEHYDRATASE-RELATED; 1.
DR   PANTHER; PTHR32329; BIFUNCTIONAL PROTEIN [INCLUDES 2-HYDROXYACYL-COA DEHYDRATASE (N-TER) AND ITS ACTIVATOR DOMAIN (C_TERM)-RELATED; 1.
DR   Pfam; PF01869; BcrAD_BadFG; 2.
DR   Pfam; PF09989; DUF2229; 1.
DR   SUPFAM; SSF53067; Actin-like ATPase domain; 2.
PE   4: Predicted;
KW   Iron {ECO:0000256|ARBA:ARBA00023014};
KW   Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00023014}.
FT   DOMAIN          6..253
FT                   /note="ATPase BadF/BadG/BcrA/BcrD type"
FT                   /evidence="ECO:0000259|Pfam:PF01869"
FT   DOMAIN          320..573
FT                   /note="ATPase BadF/BadG/BcrA/BcrD type"
FT                   /evidence="ECO:0000259|Pfam:PF01869"
FT   DOMAIN          669..885
FT                   /note="DUF2229"
FT                   /evidence="ECO:0000259|Pfam:PF09989"
SQ   SEQUENCE   1425 AA;  159993 MW;  7B8912D4BF1DFEB0 CRC64;
     MRIHMGLDVG STTVKLVILD NEFNILYSTY RRHFSDVKKT VKDVINEVYD KYKYDSLTCA
     VTGSGGLSVT KLLDVDFIQE VIAGKVAISS YIPQTDVAIE LGGEDSKITY LKGSVEQRMN
     SICAGGTGAF IDQMASLLQT DASGLNEMAK SYKKLYPIAS RCGVFAKTDV QALINQGAEK
     EDIAISVFQS VVNQTISNLA CGRPIRGNVA FLGGPLHFLN MLRERFIKTL NLKDEEIIVP
     ENSQIFVALG AAISSFETKS MPFIELFNRV NSNIKVIEKE TTTLEPLFKD KKDLEDFIED
     HKTKNLREIP ISSYKGPIFI GIDSGSTTSK LVALSDNNEI LYKYYGSNKG NPLEIVIEQL
     KEIYKKKNNE AYIASAGCTG YGEDFLKAAL NLDLGEVETI AHFTAAKFFD PEVDFILDIG
     GQDMKSMKIS DGVIESILLN EACSAGCGSF LETFARSVNL SAKEFANQAT MGENPVDLGS
     RCTVFMNSNV KQAQKEGAEV TDIAAGLAYS VIRNALQKVI KVRDPKDLGK HIVVQGGTFL
     SNAVLRAFEN LTGVKVTRPN IAGLMGALGM ALICKEKSQG KSSIIDEECL SNFKYKSIST
     NCHQCTNNCA LSINIFSNGK RYITGNRCEK GAGLVKSNEE KLPNLYKYKL ERLFSYKSLD
     EKNAPRGIVG IPRVLNIYEN YPFWHTFFTS LGYRVVLSSK SSREIYEKGI ETITSETACY
     PAKISHGHIE DLIEKGVKFI FYPAVFYEEK QFKNADDTIN CPVVAGYSEV IKNNVDKIAN
     GNIVFLNPFI SFNDRKRLEK RLNEVFTDIP YDEIKRAVRA AYQEEDRYRL DVLNEGNKAL
     SYIKEKNIKG IVLCGRPYHV DPEINHGIPE LINQLGLAVL SEDSVARNVE IDSRLRVLDQ
     WNYHSRLYRA AKFVGQYDNL ELVQLNSFGC GIDAVTTDQV AEIIKAYNKI YTVLKIDEVS
     NLGSIKIRLR SLIEASEKRE FIKKEADKLG LINEKPLLFT EEMRENYTIL MPQMSPLHFE
     IFEPILQAEG INIKVLKDSG NKVVNEGLKY VNNDACYPSM FVVGQFIDAV KSGKYDTEHL
     ALLMSQTGGA CRASNYVAFI RKALKDAGYG HIPVIGLSFQ EIESHPGFKF TRKQIIRMGK
     KLVQALLYAD LISRLTLATR PYELIKGSTN ILRDRWIEIT TSKDLSYEKE DFIRNVYTMV
     GEFKRLEISK IKKPKVGIVG EILVKYDPAA NNHLAKVLED EGAEVVIPDL TDFMMYSFKN
     QEYKYRLLSK SWLPSFVCNL GIYYIEYYRK FVSKALEGTR FTKPEKIENI IDYAKKYVSL
     GNQYGEGWLL TGEMVELIES GTENIVCVQP FGCLPNHITG KGVIKAIRST YEKANIIPLD
     FDASASSVNQ YNRIKLMLSQ AKKNMEQEKS IYHRGFLKNK VALEN
//