ID D8FSJ6_RHIFR Unreviewed; 199 AA.
AC D8FSJ6;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=nicotinamidase {ECO:0000256|ARBA:ARBA00039017};
DE EC=3.5.1.19 {ECO:0000256|ARBA:ARBA00039017};
DE AltName: Full=Nicotinamide deamidase {ECO:0000256|ARBA:ARBA00043224};
GN Name=pncA {ECO:0000313|EMBL:ADK32501.1};
GN ORFNames=GHK48_21825 {ECO:0000313|EMBL:MQX10836.1};
OS Rhizobium fredii (Sinorhizobium fredii).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX NCBI_TaxID=380 {ECO:0000313|EMBL:ADK32501.1};
RN [1] {ECO:0000313|EMBL:ADK32501.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=HH103 {ECO:0000313|EMBL:ADK32501.1};
RX PubMed=16404952; DOI=10.1094/MPMI-19-0043;
RA Parada M., Vinardell J.M., Ollero F.J., Hidalgo A., Gutierrez R.,
RA Buendia-Claveria A.M., Lei W., Margaret I., Lopez-Baena F.J.,
RA Gil-Serrano A.M., Rodriguez-Carvajal M.A., Moreno J., Ruiz-Sainz J.E.;
RT "Sinorhizobium fredii HH103 mutants affected in capsular polysaccharide
RT (KPS) are impaired for nodulation with soybean and Cajanus cajan.";
RL Mol. Plant Microbe Interact. 19:43-52(2006).
RN [2] {ECO:0000313|EMBL:ADK32501.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=HH103 {ECO:0000313|EMBL:ADK32501.1};
RA Vinardell J.M., Hidalgo A., Parada M., Margaret I., Crespo-Rivas J.C.;
RL Submitted (JUL-2010) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:MQX10836.1, ECO:0000313|Proteomes:UP000466694}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=USDA205 {ECO:0000313|EMBL:MQX10836.1,
RC ECO:0000313|Proteomes:UP000466694};
RX PubMed=23425606;
RA Sugawara M., Epstein B., Badgley B.D., Unno T., Xu L., Reese J.,
RA Gyaneshwar P., Denny R., Mudge J., Bharti A.K., Farmer A.D., May G.D.,
RA Woodward J.E., Medigue C., Vallenet D., Lajus A., Rouy Z., Martinez-Vaz B.,
RA Tiffin P., Young N.D., Sadowsky M.J.;
RT "Comparative genomics of the core and accessory genomes of 48 Sinorhizobium
RT strains comprising five genospecies.";
RL Genome Biol. 14:0-R17(2013).
RN [4] {ECO:0000313|EMBL:MQX10836.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=USDA205 {ECO:0000313|EMBL:MQX10836.1};
RA Sugawara M., Epstein B., Badgley B., Unno T., Xu L., Reese J.,
RA Gyaneshwar P., Denny R., Mudege J., Bharti A., Farmer A., May G.,
RA Woodward J., Medigue C., Vallenet D., Lajus A., Rouy Z., Martinez-Vaz B.,
RA Tiffin P., Young N., Sadowsky M.;
RL Submitted (OCT-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Cofactor biosynthesis; nicotinate biosynthesis; nicotinate
CC from nicotinamide: step 1/1. {ECO:0000256|ARBA:ARBA00037900}.
CC -!- SIMILARITY: Belongs to the isochorismatase family.
CC {ECO:0000256|ARBA:ARBA00006336}.
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DR EMBL; AY882435; ADK32501.1; -; Genomic_DNA.
DR EMBL; WISZ01000161; MQX10836.1; -; Genomic_DNA.
DR RefSeq; WP_014327256.1; NZ_WITA01000139.1.
DR AlphaFoldDB; D8FSJ6; -.
DR GeneID; 48971736; -.
DR Proteomes; UP000466694; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0019363; P:pyridine nucleotide biosynthetic process; IEA:UniProtKB-KW.
DR CDD; cd01011; nicotinamidase; 1.
DR Gene3D; 3.40.50.850; Isochorismatase-like; 1.
DR InterPro; IPR000868; Isochorismatase-like.
DR InterPro; IPR036380; Isochorismatase-like_sf.
DR PANTHER; PTHR11080:SF2; LD05707P; 1.
DR PANTHER; PTHR11080; PYRAZINAMIDASE/NICOTINAMIDASE; 1.
DR Pfam; PF00857; Isochorismatase; 1.
DR SUPFAM; SSF52499; Isochorismatase-like hydrolases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:MQX10836.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Pyridine nucleotide biosynthesis {ECO:0000256|ARBA:ARBA00022642}.
FT DOMAIN 5..198
FT /note="Isochorismatase-like"
FT /evidence="ECO:0000259|Pfam:PF00857"
SQ SEQUENCE 199 AA; 21292 MW; 029938C6D0B01E5F CRC64;
MAEDALIVID MQNDFCPGGA LAVAGGDEIV PIVNRLIEGA RHVILTQDWH PAGHSSFASS
HPGKAPFQTV TMPYGEQTLW LDHCVQGSPG ADFHPALRWT TAELVIRKGF RTGIDSYSAF
FENDHRTPTG LAGYLRERGI SKVSLCGLAT DFCVAFSALD AVAEGFSTSV VLGACRGIDL
NGSLAAMTRR MRDAGVELI
//
