ID   D8FVT4_9CYAN            Unreviewed;       528 AA.
AC   D8FVT4;
DT   05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2010, sequence version 1.
DT   27-MAR-2024, entry version 39.
DE   SubName: Full=Adenylate/guanylate cyclase {ECO:0000313|EMBL:CBN54474.1};
GN   ORFNames=OSCI_900001 {ECO:0000313|EMBL:CBN54474.1};
OS   Kamptonema sp. PCC 6506.
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
OC   Oscillatoriales; Microcoleaceae; Kamptonema.
OX   NCBI_TaxID=272129 {ECO:0000313|EMBL:CBN54474.1, ECO:0000313|Proteomes:UP000004532};
RN   [1] {ECO:0000313|Proteomes:UP000004532}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 6506 {ECO:0000313|Proteomes:UP000004532};
RX   PubMed=20675499; DOI=10.1128/JB.00704-10;
RA   Mejean A., Mazmouz R., Mann S., Calteau A., Medigue C., Ploux O.;
RT   "The genome sequence of the cyanobacterium Oscillatoria sp. PCC 6506
RT   reveals several gene clusters responsible for the biosynthesis of toxins
RT   and secondary metabolites.";
RL   J. Bacteriol. 192:5264-5265(2010).
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DR   EMBL; CACA01000087; CBN54474.1; -; Genomic_DNA.
DR   RefSeq; WP_007353699.1; NZ_CACA01000087.1.
DR   AlphaFoldDB; D8FVT4; -.
DR   OrthoDB; 526903at2; -.
DR   Proteomes; UP000004532; Unassembled WGS sequence.
DR   GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR   GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   CDD; cd07302; CHD; 2.
DR   Gene3D; 3.30.70.1230; Nucleotide cyclase; 2.
DR   InterPro; IPR001054; A/G_cyclase.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   PANTHER; PTHR16305; TESTICULAR SOLUBLE ADENYLYL CYCLASE; 1.
DR   PANTHER; PTHR16305:SF35; TRANSCRIPTIONAL ACTIVATOR DOMAIN; 1.
DR   Pfam; PF00211; Guanylate_cyc; 2.
DR   SMART; SM00044; CYCc; 2.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 2.
DR   PROSITE; PS50125; GUANYLATE_CYCLASE_2; 2.
PE   4: Predicted;
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000004532}.
FT   DOMAIN          89..226
FT                   /note="Guanylate cyclase"
FT                   /evidence="ECO:0000259|PROSITE:PS50125"
FT   DOMAIN          337..477
FT                   /note="Guanylate cyclase"
FT                   /evidence="ECO:0000259|PROSITE:PS50125"
SQ   SEQUENCE   528 AA;  57096 MW;  7D6592DDD705D879 CRC64;
     MDNSTKLTNL RINVLAYNPP LAALELKLRS LLSAELYAAA WVDPKPATLI NVFDHLRTLR
     YILNDYVPRP VSESPPKPGE VRYQWQEGTL LFTDLAGFTP LLEANAAYGR SGAEALWNLL
     HTYFASMIDI ISKSGGDLLE FTGDAMLVKF LATKDGNDTA TALRAGLRMQ RAMANFSQIE
     TPRGVLSLGM RVGIHCGKYI AADIGTPMRM AHVLLGHSVQ QAKQAEGAGT VGRVCLTETA
     SSVLADQFRF EPSKPGYLLA VDDLTDAQLG EYDIMPTRRR MPSSVLLDRS VSGLAAEIEE
     AVKRVESLAS YIPRPILTLL VENANKRQIP PDFLMPTVMF VNLIGLPESV DLATPEEAVN
     LVTSFSRVFS MVDAAVTARG GVLPNVTAHL EGSDILIYFG VPEAHTNDPY RAASAALAIR
     DIISQLTPPI VGGKQVTVFS QIGLAMGPVF AAEVGESRGR REFNVVGDTV NTAARLMTKA
     AKNQILISEK VFSAIAPHFD CEDLGAISLK GKAAPMSVFA LQKLKVNS
//