ID D8G552_9CYAN Unreviewed; 290 AA.
AC D8G552;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 24-JAN-2024, entry version 41.
DE SubName: Full=UBA/THIF-type NAD/FAD binding fold {ECO:0000313|EMBL:CBN57742.1};
GN ORFNames=OSCI_3510025 {ECO:0000313|EMBL:CBN57742.1};
OS Kamptonema sp. PCC 6506.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
OC Oscillatoriales; Microcoleaceae; Kamptonema.
OX NCBI_TaxID=272129 {ECO:0000313|EMBL:CBN57742.1, ECO:0000313|Proteomes:UP000004532};
RN [1] {ECO:0000313|EMBL:CBN57742.1, ECO:0000313|Proteomes:UP000004532}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PCC 6506 {ECO:0000313|EMBL:CBN57742.1,
RC ECO:0000313|Proteomes:UP000004532};
RX PubMed=20675499; DOI=10.1128/JB.00704-10;
RA Mejean A., Mazmouz R., Mann S., Calteau A., Medigue C., Ploux O.;
RT "The genome sequence of the cyanobacterium Oscillatoria sp. PCC 6506
RT reveals several gene clusters responsible for the biosynthesis of toxins
RT and secondary metabolites.";
RL J. Bacteriol. 192:5264-5265(2010).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CBN57742.1}.
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DR EMBL; CACA01000315; CBN57742.1; -; Genomic_DNA.
DR RefSeq; WP_007356934.1; NZ_CACA01000315.1.
DR AlphaFoldDB; D8G552; -.
DR OrthoDB; 9804286at2; -.
DR Proteomes; UP000004532; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008641; F:ubiquitin-like modifier activating enzyme activity; IEA:InterPro.
DR CDD; cd00757; ThiF_MoeB_HesA_family; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR045886; ThiF/MoeB/HesA.
DR InterPro; IPR000594; ThiF_NAD_FAD-bd.
DR InterPro; IPR035985; Ubiquitin-activating_enz.
DR PANTHER; PTHR10953:SF102; ADENYLYLTRANSFERASE AND SULFURTRANSFERASE MOCS3; 1.
DR PANTHER; PTHR10953; UBIQUITIN-ACTIVATING ENZYME E1; 1.
DR Pfam; PF00899; ThiF; 1.
DR SUPFAM; SSF69572; Activating enzymes of the ubiquitin-like proteins; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000004532};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 34..60
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 12..243
FT /note="THIF-type NAD/FAD binding fold"
FT /evidence="ECO:0000259|Pfam:PF00899"
FT REGION 252..290
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 257..271
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 290 AA; 31836 MW; 7D2187362282FF8B CRC64;
MLHLTPTELE RYRRQIMLPG FGEEAQKRLK SSTVLVTGVG GLGGTAALYL AVAGVGRLIL
VRGGELRLDD MNRQILMTDD WVGKPRVFKA KETLEEINPD VQVDAIFEYV TPENVDTLVQ
AADIVLDCAH NFIERDLLNA ACVQWDKPMV EAAMNDMEAY LTTIVPGETP CLSCIFPEKP
DWDKRGFGVI GAVSGTLACL TALEAIKLLA GIGKPLLSQL LTMDLGSLEF AKRRPYHDPN
CPVCSHKSRD KLESKLNQKF PTPNPSRSSA TKREKPGIPL PQNSLPIAIS
//
