ID D8G774_9CYAN Unreviewed; 299 AA.
AC D8G774;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=Succinyl-CoA synthetase (ADP-forming) alpha subunit {ECO:0000313|EMBL:CBN58464.1};
DE EC=6.2.1.5 {ECO:0000313|EMBL:CBN58464.1};
GN ORFNames=OSCI_3790020 {ECO:0000313|EMBL:CBN58464.1};
OS Kamptonema sp. PCC 6506.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
OC Oscillatoriales; Microcoleaceae; Kamptonema.
OX NCBI_TaxID=272129 {ECO:0000313|EMBL:CBN58464.1, ECO:0000313|Proteomes:UP000004532};
RN [1] {ECO:0000313|Proteomes:UP000004532}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PCC 6506 {ECO:0000313|Proteomes:UP000004532};
RX PubMed=20675499; DOI=10.1128/JB.00704-10;
RA Mejean A., Mazmouz R., Mann S., Calteau A., Medigue C., Ploux O.;
RT "The genome sequence of the cyanobacterium Oscillatoria sp. PCC 6506
RT reveals several gene clusters responsible for the biosynthesis of toxins
RT and secondary metabolites.";
RL J. Bacteriol. 192:5264-5265(2010).
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DR EMBL; CACA01000343; CBN58464.1; -; Genomic_DNA.
DR RefSeq; WP_007357642.1; NZ_CACA01000343.1.
DR AlphaFoldDB; D8G774; -.
DR OrthoDB; 9807196at2; -.
DR Proteomes; UP000004532; Unassembled WGS sequence.
DR GO; GO:0004775; F:succinate-CoA ligase (ADP-forming) activity; IEA:UniProtKB-EC.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 3.40.50.261; Succinyl-CoA synthetase domains; 1.
DR InterPro; IPR003781; CoA-bd.
DR InterPro; IPR005810; CoA_lig_alpha.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR005811; SUCC_ACL_C.
DR InterPro; IPR016102; Succinyl-CoA_synth-like.
DR PANTHER; PTHR11117:SF2; SUCCINATE--COA LIGASE [ADP_GDP-FORMING] SUBUNIT ALPHA, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11117; SUCCINYL-COA LIGASE SUBUNIT ALPHA; 1.
DR Pfam; PF02629; CoA_binding; 1.
DR Pfam; PF00549; Ligase_CoA; 1.
DR PIRSF; PIRSF001553; SucCS_alpha; 1.
DR PRINTS; PR01798; SCOASYNTHASE.
DR SMART; SM00881; CoA_binding; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF52210; Succinyl-CoA synthetase domains; 1.
PE 4: Predicted;
KW Ligase {ECO:0000313|EMBL:CBN58464.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000004532}.
FT DOMAIN 2..100
FT /note="CoA-binding"
FT /evidence="ECO:0000259|SMART:SM00881"
FT ACT_SITE 247
FT /note="Tele-phosphohistidine intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR001553-1"
SQ SEQUENCE 299 AA; 31138 MW; 185AEAFE33DBDECF CRC64;
MNLTPQTKVL VQGITESPAS TQAALMMKAY GTNVVAGVSP GLGGQELHGI PVFDLVEQAL
SAFGKIDTSV IFVHPYSVLD AALEAIAAGI QQIVIVTEGV PPLDMVRLVR KAEATETLVV
GPNCPGIIVP DKLLLGTHPS EFYTPGPVGL ISRSNTLTYE IALQLTNAKL GQSIGVSIGS
DVIVGSSFMQ WLQILDEDDS TDAIVLVGEV GSGSEEAAAS YIAEAIDKPV IAYIAGRYAP
KGQPLGHAGT LISSRAAVRT TEAGTAESKI AAFQEAKIPV AERISQIPEL VKKALKKSG
//
