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Database: UniProt
Entry: D8ITP0_HERSS
LinkDB: D8ITP0_HERSS
Original site: D8ITP0_HERSS 
ID   D8ITP0_HERSS            Unreviewed;       465 AA.
AC   D8ITP0;
DT   05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2010, sequence version 1.
DT   25-OCT-2017, entry version 51.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377,
GN   ECO:0000313|EMBL:ADJ61531.1};
GN   OrderedLocusNames=Hsero_0001 {ECO:0000313|EMBL:ADJ61531.1};
OS   Herbaspirillum seropedicae (strain SmR1).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Oxalobacteraceae; Herbaspirillum.
OX   NCBI_TaxID=757424 {ECO:0000313|EMBL:ADJ61531.1, ECO:0000313|Proteomes:UP000000329};
RN   [1] {ECO:0000313|EMBL:ADJ61531.1, ECO:0000313|Proteomes:UP000000329}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SmR1 {ECO:0000313|EMBL:ADJ61531.1,
RC   ECO:0000313|Proteomes:UP000000329};
RA   Pedrosa F.O., Monteiro R.A., Wassem R., Cruz L.M., Ayub R.A.,
RA   Colauto N.B., Fernandez M.A., Fungaro M.H.P., Grisard E.C.,
RA   Hungria M., Madeira H.M.F., Nodari R.O., Osaku C.A., Petzl-Erler M.L.,
RA   Terenzi H., Vieira L.G.E., Almeida M.I.M., Alves L.R., Arantes O.M.N.,
RA   Balsanelli E., Barcellos F.G., Baura V.A., Binde D.R., Campo R.J.,
RA   Chubatsu L.S., Chueire L.M.O., Ciferri R.R., Correa L.C.,
RA   da Conceicao Silva J.L., Dabul A.N.G., Dambros B.P., Faoro H.,
RA   Favetti A., Friedermann G., Furlaneto M.C., Gasques L.S.,
RA   Gimenes C.C.T., Gioppo N.M.R., Glienke-Blanco C., Godoy L.P.,
RA   Guerra M.P., Karp S., Kava-Cordeiro V., Margarido V.P., Mathioni S.M.,
RA   Menck-Soares M.A., Murace N.K., Nicolas M.F., Oliveira C.E.C.,
RA   Pagnan N.A.B., Pamphile J.A., Patussi E.V., Pereira L.F.P.,
RA   Pereira-Ferrari L., Pinto F.G.S., Precoma C., Prioli A.J.,
RA   Prioli S.M.A.P., Raittz R.T., Ramos H.J.O., Ribeiro E.M.S.F.,
RA   Rigo L.U., Rocha C.L.M.S.C., Rocha S.N., Santos K., Satori D.,
RA   Silva A.G., Simao R.C.G., Soares M.A.M., Souza E.M., Steffens M.B.R.,
RA   Steindel M., Tadra-Sfeir M.Z., Takahashi E.K., Torres R.A.,
RA   Valle J.S., Vernal J.I., Vilas-Boas L.A., Watanabe M.A.E., Weiss V.A.,
RA   Yates M.A., Souza E.M.;
RT   "The genome of Herbaspirillum seropedicae SmR1, an endophytic,
RT   nitrogen-fixing, plant-growth promoting beta-Proteobacteria.";
RL   Submitted (APR-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00911680}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
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DR   EMBL; CP002039; ADJ61531.1; -; Genomic_DNA.
DR   RefSeq; WP_013232086.1; NC_014323.1.
DR   STRING; 757424.Hsero_0001; -.
DR   EnsemblBacteria; ADJ61531; ADJ61531; Hsero_0001.
DR   GeneID; 29389668; -.
DR   KEGG; hse:Hsero_0001; -.
DR   eggNOG; ENOG4105CI4; Bacteria.
DR   eggNOG; COG0593; LUCA.
DR   HOGENOM; HOG000235659; -.
DR   KO; K02313; -.
DR   OMA; REFNPLF; -.
DR   OrthoDB; POG091H02FF; -.
DR   Proteomes; UP000000329; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747950};
KW   Complete proteome {ECO:0000313|Proteomes:UP000000329};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00911664};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00911684};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747895};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000329}.
FT   DOMAIN      162    293       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      373    442       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     170    177       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   465 AA;  52119 MW;  F4AD6870F808A99D CRC64;
     MENFWQACSQ KLEQELTPQQ YSAWIKPLVP LDYEDGLLRV AAPNRFKLDW VKTQFANRIT
     ALACEYWDAP TEVQFVLDPR GNQGRRPAAA AAAGNGASGL GLPNHEQLHL DPEPAQPVRA
     VAPRQEQSRI NPVLTFDNLV TGKANQLARA AATQVANNPG TSYNPLFLYG GVGLGKTHII
     HAIGNQVLVD NPGAKIRYIH AEQYVRDVVT AYQRKGFDDF KRYYHSLDLL LIDDIQFFGG
     KSRTQEEFFY AFEALIAAKK QIIITSDTYP KEISGMDDRL ISRFDSGLTV AIEPPELEMR
     VAILMKKASA EDVVLSDDVA FFVAKHLRSN VRELEGALRK ILAYSRFHGK DITIDVVKEA
     LKDLLSVQNR QISVENIQKT VADFFNIKVA DMYSKKRPAN IARPRQIAMY LAKELTQKSL
     PEIGDLFGGR DHTTVLHAVR KIAADRAKSP ECNHELHVLE QTLKG
//
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