ID D8J832_HALJB Unreviewed; 609 AA.
AC D8J832;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=TrkA-C domain protein {ECO:0000313|EMBL:ADJ14145.1};
DE SubName: Full=TrkA-C domain-containing protein {ECO:0000313|EMBL:ELY34673.1};
GN OrderedLocusNames=HacjB3_03770 {ECO:0000313|EMBL:ADJ14145.1};
GN ORFNames=C497_15523 {ECO:0000313|EMBL:ELY34673.1};
OS Halalkalicoccus jeotgali (strain DSM 18796 / CECT 7217 / JCM 14584 / KCTC
OS 4019 / B3).
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC Halococcaceae; Halalkalicoccus.
OX NCBI_TaxID=795797 {ECO:0000313|EMBL:ADJ14145.1, ECO:0000313|Proteomes:UP000000390};
RN [1] {ECO:0000313|EMBL:ADJ14145.1, ECO:0000313|Proteomes:UP000000390}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B3 {ECO:0000313|EMBL:ADJ14145.1}, and DSM 18796 / CECT 7217 /
RC JCM 14584 / KCTC 4019 / B3 {ECO:0000313|Proteomes:UP000000390};
RX PubMed=20601480; DOI=10.1128/JB.00663-10;
RA Roh S.W., Nam Y.D., Nam S.H., Choi S.H., Park H.S., Bae J.W.;
RT "Complete genome sequence of Halalkalicoccus jeotgali B3(T), an extremely
RT halophilic archaeon.";
RL J. Bacteriol. 192:4528-4529(2010).
RN [2] {ECO:0000313|Proteomes:UP000011645}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B3 {ECO:0000313|Proteomes:UP000011645};
RA Becker E.A., Seitzer P., Tritt A., Larsen D., Yao A., Wu D., Darling A.,
RA Eisen J.A., Facciotti M.T.;
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:ELY34673.1, ECO:0000313|Proteomes:UP000011645}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B3 {ECO:0000313|EMBL:ELY34673.1,
RC ECO:0000313|Proteomes:UP000011645};
RX PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT strategies for static and dynamic osmo-response.";
RL PLoS Genet. 10:E1004784-E1004784(2014).
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DR EMBL; CP002062; ADJ14145.1; -; Genomic_DNA.
DR EMBL; AOHV01000040; ELY34673.1; -; Genomic_DNA.
DR AlphaFoldDB; D8J832; -.
DR STRING; 795797.HacjB3_03770; -.
DR KEGG; hje:HacjB3_03770; -.
DR eggNOG; arCOG01960; Archaea.
DR HOGENOM; CLU_448066_0_0_2; -.
DR Proteomes; UP000000390; Chromosome.
DR Proteomes; UP000011645; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR Gene3D; 3.30.70.1450; Regulator of K+ conductance, C-terminal domain; 1.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR006037; RCK_C.
DR InterPro; IPR036721; RCK_C_sf.
DR InterPro; IPR003148; RCK_N.
DR PANTHER; PTHR43833; POTASSIUM CHANNEL PROTEIN 2-RELATED-RELATED; 1.
DR PANTHER; PTHR43833:SF5; TRK SYSTEM POTASSIUM UPTAKE PROTEIN TRKA; 1.
DR Pfam; PF02080; TrkA_C; 1.
DR Pfam; PF02254; TrkA_N; 2.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 2.
DR SUPFAM; SSF116726; TrkA C-terminal domain-like; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
DR PROSITE; PS51202; RCK_C; 1.
DR PROSITE; PS51201; RCK_N; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..40
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 126..246
FT /note="RCK N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51201"
FT DOMAIN 258..342
FT /note="RCK C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51202"
FT DOMAIN 353..463
FT /note="RCK N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51201"
FT REGION 431..609
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 432..550
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 609 AA; 67050 MW; DDABA389B86E68A1 CRC64;
MRSLADFKNV RSYEDLSRRQ RLLLGYAAGL VCVILFYTVV YNAGMRALEG ESHSLFRSFQ
TVVETMTTTG YGADSPWSTP WMNVFVVTMQ LSGIAIGFFT LRVLVIPLFE RTSLDLDDRL
TPKDDHVVIG EYRRDSDVLL DELERLGIDY VLVDSDAEEA KRLSDDGYQV IHGDPETVET
LERASIHEAT LLVTDAGDRN ASIVLSALDL NGGLRVASLT ESTRRNDALE RIGVDTAISP
HVLIGRRLAY KATTSVAFPE GTSLDEDVEI REVLVRRQSP LRGTKVRDTP FFDHPNVTLV
AGWFDGDLRL PPDPSDRLMP NTVLLLAGPK DAIDDVHADL SGTGLRTTRE HTSVLVAGAG
EGGRAVVETL PEDVSTTTVD VDDHEGVDVV GDVGDPGTLT EAGIADATAL VVTVDDDATA
LLTIALARSL AQREPRDPRA RDRRGQGPHG IQRRGRLRAV DPTGDRATAR PRGLRRGRRL
AGEPDPPHPH RRGPPRRSVD RRGQRGLRDR LGDRCPRTRR RVPDRRDDRH SGGRYGSRGR
NRRDDPGVRG GNDRLVAVRP IRASRSSPVR IASEKCPGRA PNPRSPHDPD SSRGTARGYG
RLPRQPPRL
//
