ID D8JUG3_HYPDA Unreviewed; 660 AA.
AC D8JUG3;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=Diguanylate cyclase/phosphodiesterase {ECO:0000313|EMBL:ADJ22753.1};
GN OrderedLocusNames=Hden_0939 {ECO:0000313|EMBL:ADJ22753.1};
OS Hyphomicrobium denitrificans (strain ATCC 51888 / DSM 1869 / NCIMB 11706 /
OS TK 0415).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Hyphomicrobiaceae; Hyphomicrobium.
OX NCBI_TaxID=582899 {ECO:0000313|EMBL:ADJ22753.1, ECO:0000313|Proteomes:UP000002033};
RN [1] {ECO:0000313|Proteomes:UP000002033}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51888 / DSM 1869 / NCIB 11706 / TK 0415
RC {ECO:0000313|Proteomes:UP000002033};
RX PubMed=21705585; DOI=10.1128/JB.05453-11;
RG US DOE Joint Genome Institute;
RA Brown P.J., Kysela D.T., Buechlein A., Hemmerich C., Brun Y.V.;
RT "Genome sequences of eight morphologically diverse alphaproteobacteria.";
RL J. Bacteriol. 193:4567-4568(2011).
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DR EMBL; CP002083; ADJ22753.1; -; Genomic_DNA.
DR RefSeq; WP_013214968.1; NC_014313.1.
DR AlphaFoldDB; D8JUG3; -.
DR STRING; 582899.Hden_0939; -.
DR KEGG; hdn:Hden_0939; -.
DR eggNOG; COG5001; Bacteria.
DR HOGENOM; CLU_000445_70_49_5; -.
DR OrthoDB; 9814202at2; -.
DR Proteomes; UP000002033; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR PANTHER; PTHR44757:SF2; BIOFILM ARCHITECTURE MAINTENANCE PROTEIN MBAA; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002033};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 32..50
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 56..74
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 95..114
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 175..200
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 255..388
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 397..649
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 660 AA; 70988 MW; 557005DEA66F0106 CRC64;
MLRVLNAVRR EDLARVHRDQ LASLARATPT AMAGYAINVL IAVVAFRGLI PGVELAAWAV
ASLAICSFIG LRSVTRSLRT RQAEASKPGS PLRDGRWALL IALMSSLPWA ILATRWVGAV
HGDSELILMA LTVGMAASGS VLLAPIPAAA VLYATAILLP PALKCILFVP GHQYLGLGAL
AVSFLVFLYG LIVTTGRLFL ERLEAITRLQ DTIAALSEAR EETERVAMTD GLTGIANRRA
FMARLNALNN RAGAKSFSIF YIDLDRFKSV NDALGHAVGD ALLKSVSARI TGLVREGDLV
ARLGGDEFAI VAQDIRERAF ASSLAERLVV SLSEPYDLEG QKVQIGACVG VALACESGVG
GEMLLKQADL AMFAAKEAGR GMYCIFEADM QRSADEHRVL ELGLRAALVN DGFELFYQPV
RNLETNAITS FECQVRWRHP LRGLLTPAQF LATAIDIGIA EDIGNWVIKE ACRQAAHWPS
EVPVGINMSS MRIGVENIAV SVERALKSAG LPPSRLELEM EVTEASLMNA DAEVIASLRR
LKDIGVSIAL DDFGTGYSSL GYLVKFPFNR IKIDRLFVSQ LGQSAQSELI VRSIAELAQR
LNCSVVAEGI ETDDQRRRVL ALDVTYGQGM LLGAPLSASE AAVLLMSEAP DPALQLAQSA
//
