ID D8LIC9_ECTSI Unreviewed; 1383 AA.
AC D8LIC9;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE RecName: Full=Bromo domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=Esi_0022_0034 {ECO:0000313|EMBL:CBN79968.1};
OS Ectocarpus siliculosus (Brown alga) (Conferva siliculosa).
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; PX clade; Phaeophyceae;
OC Ectocarpales; Ectocarpaceae; Ectocarpus.
OX NCBI_TaxID=2880 {ECO:0000313|EMBL:CBN79968.1, ECO:0000313|Proteomes:UP000002630};
RN [1] {ECO:0000313|EMBL:CBN79968.1, ECO:0000313|Proteomes:UP000002630}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ec32 / CCAP1310/4 {ECO:0000313|Proteomes:UP000002630};
RX PubMed=20520714; DOI=10.1038/nature09016;
RA Cock J.M., Sterck L., Rouze P., Scornet D., Allen A.E., Amoutzias G.,
RA Anthouard V., Artiguenave F., Aury J.M., Badger J.H., Beszteri B.,
RA Billiau K., Bonnet E., Bothwell J.H., Bowler C., Boyen C., Brownlee C.,
RA Carrano C.J., Charrier B., Cho G.Y., Coelho S.M., Collen J., Corre E.,
RA Da Silva C., Delage L., Delaroque N., Dittami S.M., Doulbeau S., Elias M.,
RA Farnham G., Gachon C.M., Gschloessl B., Heesch S., Jabbari K., Jubin C.,
RA Kawai H., Kimura K., Kloareg B., Kupper F.C., Lang D., Le Bail A.,
RA Leblanc C., Lerouge P., Lohr M., Lopez P.J., Martens C., Maumus F.,
RA Michel G., Miranda-Saavedra D., Morales J., Moreau H., Motomura T.,
RA Nagasato C., Napoli C.A., Nelson D.R., Nyvall-Collen P., Peters A.F.,
RA Pommier C., Potin P., Poulain J., Quesneville H., Read B., Rensing S.A.,
RA Ritter A., Rousvoal S., Samanta M., Samson G., Schroeder D.C., Segurens B.,
RA Strittmatter M., Tonon T., Tregear J.W., Valentin K., von Dassow P.,
RA Yamagishi T., Van de Peer Y., Wincker P.;
RT "The Ectocarpus genome and the independent evolution of multicellularity in
RT brown algae.";
RL Nature 465:617-621(2010).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; FN648398; CBN79968.1; -; Genomic_DNA.
DR STRING; 2880.D8LIC9; -.
DR EnsemblProtists; CBN79968; CBN79968; Esi_0022_0034.
DR eggNOG; ENOG502QUXV; Eukaryota.
DR InParanoid; D8LIC9; -.
DR OrthoDB; 1216145at2759; -.
DR Proteomes; UP000002630; Unplaced LGUn.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR CDD; cd00018; AP2; 1.
DR CDD; cd04369; Bromodomain; 1.
DR CDD; cd05162; PWWP; 1.
DR Gene3D; 2.30.30.140; -; 1.
DR Gene3D; 3.30.730.10; AP2/ERF domain; 1.
DR Gene3D; 1.20.920.10; Bromodomain-like; 1.
DR InterPro; IPR001471; AP2/ERF_dom.
DR InterPro; IPR036955; AP2/ERF_dom_sf.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR InterPro; IPR016177; DNA-bd_dom_sf.
DR InterPro; IPR000313; PWWP_dom.
DR PANTHER; PTHR31677; AP2 DOMAIN CLASS TRANSCRIPTION FACTOR; 1.
DR PANTHER; PTHR31677:SF127; ETHYLENE-RESPONSIVE TRANSCRIPTION FACTOR ERF105; 1.
DR Pfam; PF00847; AP2; 1.
DR Pfam; PF00439; Bromodomain; 1.
DR Pfam; PF00855; PWWP; 1.
DR SMART; SM00380; AP2; 1.
DR SMART; SM00297; BROMO; 1.
DR SUPFAM; SSF47370; Bromodomain; 1.
DR SUPFAM; SSF54171; DNA-binding domain; 1.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 1.
DR PROSITE; PS51032; AP2_ERF; 1.
DR PROSITE; PS50014; BROMODOMAIN_2; 1.
DR PROSITE; PS50812; PWWP; 1.
PE 4: Predicted;
KW Bromodomain {ECO:0000256|PROSITE-ProRule:PRU00035};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000002630};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 8..82
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT DOMAIN 311..394
FT /note="PWWP"
FT /evidence="ECO:0000259|PROSITE:PS50812"
FT DOMAIN 836..896
FT /note="AP2/ERF"
FT /evidence="ECO:0000259|PROSITE:PS51032"
FT REGION 390..410
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 431..548
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 666..692
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 747..842
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 891..1015
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1197..1252
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 694..721
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 447..513
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 789..818
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 934..950
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1218..1232
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1383 AA; 141534 MW; 5A276C07A0218D82 CRC64;
MNILRLLAGS PLSEEFRKPV VQLHPELAER YTVEVRRPID LTTVARRVRR GTYDNSAGRL
RRDIARIFTN CERFNMCSGQ LFVGIARHLR ALFESKWAES DLPYPGESQA TSHRRRAALR
TARYRLCWRA QLRGPLREAA RQAVRAASAA ALAAGGPGAN GVSREFSEDI LPMLSGEGEE
SNEEWTLGLF AERACLALGL RANQPPPVEE ACPGGGGEAA AAAAAAAAGE KAGRDACADW
LFGPRQAAWL AAETAPAGEK RDPASAPPPV ATAAVVSAAW RALDGALSPA TVLVASNAAR
GTPFSSVWAR PDKLVWAKQA KNTFWPAMLL WGSGTTAALK EVNMGRVPPA FREELEKQAK
GTKGNNRNGA VVEFFGLHEF ALLKPDALRP LSTLDKSPNK TVSKNKRWDP TMEEARKAVV
NLRDLETSMY MPQPEPAAGL NGLTMEPSSE ELHQTGTPAS DTDTSSGEST LESDTESNAD
LASPPTAECS SSSCSSSSSS PFPAPSCTAA VAGSASSVGG PHRDSLGGGG APSSLRAMSP
PPPPTRATLL LLSTGVSHFE GLNAAGGGKG RSGGLSAWRL ALKRPLEELT PKERALEKVC
RYLDKFGDMF SPQAQLKAAA EARDKDKAAM LGGRGHNNAP SAPAAAAVLG QTGLWGSLMG
APAKVEEETE STDGEDEDIG MIDSEGPNKC ADRKAALRRQ QEILRKDIEN LQARAVLQEK
RLNGLGAAIP PHAARQAKRD REWREFLDRR TSDSSAATAS PRPSASEGSA KHPPASPAAS
GTAVPASSGA AAAGTSQATP SSANGGDSAS SPGCSSLSRG SGDRGGGAAG ASSSSRAYGS
SAFRGVNLNG NRWLARISQD GKKKSLGGYA TEEEAAKAYD RAALQLFGPG AVTNFKDGKR
VQLEGRSQRS GGGGGGSGGA CKPKPSPAAR PVDAAKEPVE RPREEQDSGD AVSSQEACST
PAKPPVASPE NTPDSLETPK EAVAAASAEE ANGGASAPES ENVDIGGSTP SDPLLEVGAA
DHADEEEMDV VTPAAAAAAV PSSEKVVPSS APESLSEPGV PPGYVSVFQG HSAPVVAAAA
AYAHPGFAPP APAGSADTVM WPGPAPAGHP GFNPYGAASV GNAYGLQYGG APAGYRQAQH
SPTGIASGLA AAAAAAAAAA AAAEHNQALM NGKGPPAAYS AAAPGYGMYG AHPVFFHGQQ
PGSSDGASGF ALSAPSAMPG MPQQQGAQQD HKSVNPPPKA PSPLTVAAPS SGGAAGQGYS
QAALVNIQGG HLNVAQAAAA AQAAAECGGP GSPARLMYAA AAAAAAAGGA AGGVYAHDAG
GAVHHYYPGG AGAVPLVAEQ RQERHQALAQ QRQEELTLAA QQRFYDEYRR ANGLESRGGQ
APR
//
