ID D8LL58_ECTSI Unreviewed; 1155 AA.
AC D8LL58;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=NB-ARC and TPR repeat-containing protein {ECO:0000313|EMBL:CBN79677.1};
GN ORFNames=Esi_0322_0028 {ECO:0000313|EMBL:CBN79677.1};
OS Ectocarpus siliculosus (Brown alga) (Conferva siliculosa).
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; PX clade; Phaeophyceae;
OC Ectocarpales; Ectocarpaceae; Ectocarpus.
OX NCBI_TaxID=2880 {ECO:0000313|EMBL:CBN79677.1, ECO:0000313|Proteomes:UP000002630};
RN [1] {ECO:0000313|EMBL:CBN79677.1, ECO:0000313|Proteomes:UP000002630}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ec32 / CCAP1310/4 {ECO:0000313|Proteomes:UP000002630};
RX PubMed=20520714; DOI=10.1038/nature09016;
RA Cock J.M., Sterck L., Rouze P., Scornet D., Allen A.E., Amoutzias G.,
RA Anthouard V., Artiguenave F., Aury J.M., Badger J.H., Beszteri B.,
RA Billiau K., Bonnet E., Bothwell J.H., Bowler C., Boyen C., Brownlee C.,
RA Carrano C.J., Charrier B., Cho G.Y., Coelho S.M., Collen J., Corre E.,
RA Da Silva C., Delage L., Delaroque N., Dittami S.M., Doulbeau S., Elias M.,
RA Farnham G., Gachon C.M., Gschloessl B., Heesch S., Jabbari K., Jubin C.,
RA Kawai H., Kimura K., Kloareg B., Kupper F.C., Lang D., Le Bail A.,
RA Leblanc C., Lerouge P., Lohr M., Lopez P.J., Martens C., Maumus F.,
RA Michel G., Miranda-Saavedra D., Morales J., Moreau H., Motomura T.,
RA Nagasato C., Napoli C.A., Nelson D.R., Nyvall-Collen P., Peters A.F.,
RA Pommier C., Potin P., Poulain J., Quesneville H., Read B., Rensing S.A.,
RA Ritter A., Rousvoal S., Samanta M., Samson G., Schroeder D.C., Segurens B.,
RA Strittmatter M., Tonon T., Tregear J.W., Valentin K., von Dassow P.,
RA Yamagishi T., Van de Peer Y., Wincker P.;
RT "The Ectocarpus genome and the independent evolution of multicellularity in
RT brown algae.";
RL Nature 465:617-621(2010).
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}.
CC -!- SIMILARITY: Belongs to the kinesin light chain family.
CC {ECO:0000256|ARBA:ARBA00009622}.
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DR EMBL; FN648512; CBN79677.1; -; Genomic_DNA.
DR AlphaFoldDB; D8LL58; -.
DR STRING; 2880.D8LL58; -.
DR EnsemblProtists; CBN79677; CBN79677; Esi_0322_0028.
DR eggNOG; KOG1840; Eukaryota.
DR eggNOG; KOG4658; Eukaryota.
DR InParanoid; D8LL58; -.
DR OrthoDB; 1753200at2759; -.
DR Proteomes; UP000002630; Unplaced LGUn.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005871; C:kinesin complex; IEA:InterPro.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 4.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR048975; APAF1_WHD.
DR InterPro; IPR002151; Kinesin_light.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR45783; KINESIN LIGHT CHAIN; 1.
DR PANTHER; PTHR45783:SF3; KINESIN LIGHT CHAIN; 1.
DR Pfam; PF21296; APAF-1-like_WHD; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF13374; TPR_10; 2.
DR Pfam; PF13424; TPR_12; 5.
DR PRINTS; PR00381; KINESINLIGHT.
DR SMART; SM00028; TPR; 11.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48452; TPR-like; 4.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00023212};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175};
KW Reference proteome {ECO:0000313|Proteomes:UP000002630};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803}.
FT DOMAIN 252..474
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
FT DOMAIN 498..558
FT /note="Apoptotic protease-activating factor 1 winged-helix"
FT /evidence="ECO:0000259|Pfam:PF21296"
SQ SEQUENCE 1155 AA; 125820 MW; B5DDEB7A126210E3 CRC64;
MAARAPSSGG SVQAGGTAEP VTAEYSFGGL HCSWTTLGIG SGQMLQEVER LLASRKPWPA
FVQAGLQARY EWNNCPEAVG EALEWMASAT VGLLDMASVG PLTPVCKAFT SLIEAAEGAI
EVAKNLEELV SWCSFLVGVF IEHGKQEDNL RPIAKPMKDF VATTIELAKR AKAMGARGKC
TALLCHRRDG KQVQDFDVKL RHIWDDIQGV TLLAFYSDFR ATLPPKTAYM ARVPKNAKQL
PPAFVERRDL FKAVVKDLVA TDRATNAAHV LRGMPGGGKT IAAKAVVRCE DVRRSFKDGI
FWVQVGQVGT GNPMALLQGL ARDLAHAPSH QPHTVPHEFV DVEHAVSHLE GVRKERNLRC
LVVLDDVWDA QIVPLFLCGG FHSLVTTRDL AVIPRDLQGV CTEVEMLTNA EALELLKNAS
RATAAIPTNE GLKVAKDCGF LPLPLAIVGA MGSSRADPDS AETWRGIHAL LQQEPELVQD
PVGSVLAVSF CGLKGAARTR FRKLGVLAKG ARAPVDMVAH LWELDHDDST LLLDDLVDKS
LVKVEEHAYY LHDLVLDFAK DELRKLKERV RLVTCRQAQY LGRMSVVKDY AKAGEVMGGF
YALMALWRSV EDLSGDNQLE ASTYGATVKP SEESEASEDV AYLTWAVGRL FELQGKFAEA
EELYDRCQAI NEEALGPEHP SVATTLHGRA GLMVKQGKLA EAEALYDRCQ AIEEKVLDPE
HPSVATTLHG RAGLMVEQGK LAEAEALYDR CQAIEEKVLG PEHPSVAATL HSRAGLMVEQ
GKLAEAEALY DRCQAIDEKV LGPEHPSVAT TLHNRACLLE QQGKLAEAEA LYDRCQAIEE
KVLGPEHPSV ATTLHNRACL LEQQGKLAEA EALYDRCQAI EEKVLGPEHP SVATTLHNRA
GLLEQQGKLA EAEALYDRCQ AMKEKVLGPE HPSVATTLHN RAGLMVEQGK LAEAEALYDR
CQAIEEKVLG PEHPSVATTL HNRAGLMVEQ GKLAEAEALY DRCQAIEEKV LGPEHPSVAT
TLHNRAGLMV EQGKLAEAEA LYDRCQAMKE KVLGPEHPSV ATTLHGRAGL MVEQGKLAEA
EALYDRCQAM KEKVLGPEHS NVATTLHSRA GLMVKQGKRD QAVPLLERAF SIRMKALGSS
HPDTIATQNQ LEHGQ
//
