ID D8LLL8_ECTSI Unreviewed; 485 AA.
AC D8LLL8;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Sulfotransferase {ECO:0000313|EMBL:CBN74649.1};
DE EC=2.8.2.- {ECO:0000313|EMBL:CBN74649.1};
GN ORFNames=Esi_0037_0054 {ECO:0000313|EMBL:CBN74649.1};
OS Ectocarpus siliculosus (Brown alga) (Conferva siliculosa).
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; PX clade; Phaeophyceae;
OC Ectocarpales; Ectocarpaceae; Ectocarpus.
OX NCBI_TaxID=2880 {ECO:0000313|EMBL:CBN74649.1, ECO:0000313|Proteomes:UP000002630};
RN [1] {ECO:0000313|EMBL:CBN74649.1, ECO:0000313|Proteomes:UP000002630}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ec32 / CCAP1310/4 {ECO:0000313|Proteomes:UP000002630};
RX PubMed=20520714; DOI=10.1038/nature09016;
RA Cock J.M., Sterck L., Rouze P., Scornet D., Allen A.E., Amoutzias G.,
RA Anthouard V., Artiguenave F., Aury J.M., Badger J.H., Beszteri B.,
RA Billiau K., Bonnet E., Bothwell J.H., Bowler C., Boyen C., Brownlee C.,
RA Carrano C.J., Charrier B., Cho G.Y., Coelho S.M., Collen J., Corre E.,
RA Da Silva C., Delage L., Delaroque N., Dittami S.M., Doulbeau S., Elias M.,
RA Farnham G., Gachon C.M., Gschloessl B., Heesch S., Jabbari K., Jubin C.,
RA Kawai H., Kimura K., Kloareg B., Kupper F.C., Lang D., Le Bail A.,
RA Leblanc C., Lerouge P., Lohr M., Lopez P.J., Martens C., Maumus F.,
RA Michel G., Miranda-Saavedra D., Morales J., Moreau H., Motomura T.,
RA Nagasato C., Napoli C.A., Nelson D.R., Nyvall-Collen P., Peters A.F.,
RA Pommier C., Potin P., Poulain J., Quesneville H., Read B., Rensing S.A.,
RA Ritter A., Rousvoal S., Samanta M., Samson G., Schroeder D.C., Segurens B.,
RA Strittmatter M., Tonon T., Tregear J.W., Valentin K., von Dassow P.,
RA Yamagishi T., Van de Peer Y., Wincker P.;
RT "The Ectocarpus genome and the independent evolution of multicellularity in
RT brown algae.";
RL Nature 465:617-621(2010).
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DR EMBL; FN648564; CBN74649.1; -; Genomic_DNA.
DR AlphaFoldDB; D8LLL8; -.
DR SMR; D8LLL8; -.
DR EnsemblProtists; CBN74649; CBN74649; Esi_0037_0054.
DR eggNOG; KOG3704; Eukaryota.
DR InParanoid; D8LLL8; -.
DR OrthoDB; 37019at2759; -.
DR Proteomes; UP000002630; Unplaced LGUn.
DR GO; GO:0008146; F:sulfotransferase activity; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR037359; NST/OST.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000863; Sulfotransferase_dom.
DR PANTHER; PTHR10605:SF56; BIFUNCTIONAL HEPARAN SULFATE N-DEACETYLASE_N-SULFOTRANSFERASE; 1.
DR PANTHER; PTHR10605; HEPARAN SULFATE SULFOTRANSFERASE; 1.
DR Pfam; PF00685; Sulfotransfer_1; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002630};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000313|EMBL:CBN74649.1}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..485
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003117264"
FT DOMAIN 173..420
FT /note="Sulfotransferase"
FT /evidence="ECO:0000259|Pfam:PF00685"
FT REGION 22..151
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 23..37
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 77..100
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 180
FT /note="For sulfotransferase activity"
FT /evidence="ECO:0000256|PIRSR:PIRSR637359-1"
FT BINDING 286
FT /ligand="3'-phosphoadenylyl sulfate"
FT /ligand_id="ChEBI:CHEBI:58339"
FT /evidence="ECO:0000256|PIRSR:PIRSR637359-2"
FT BINDING 294
FT /ligand="3'-phosphoadenylyl sulfate"
FT /ligand_id="ChEBI:CHEBI:58339"
FT /evidence="ECO:0000256|PIRSR:PIRSR637359-2"
SQ SEQUENCE 485 AA; 52453 MW; A56AD70C3B1906E2 CRC64;
MVAAVVSLVL ALAFLPIILT GPSDPATPMP PMPATPPDDL DSGGGVADPG REKPAPPAAS
ASGVARRVEL AAAAVAGRGS SSSSSSSASY SDNHESRQGF DGQQSWRREQ EEGGGGGWAG
GGDSGVPEDL SAGRAAGGGA TGVVAEGEGG KLRDGRNRCF VGAEGDHRCY PTVFFFGTSK
CGTTSLARWL DHHPATHWVA NPRRPHQIEE TGVKEAHVFD DPPKGDPAFE EGMHHEKLFI
TTPKSGAEDV VIDYTPHYIA VAETPHRIAD IYGGRESGLK FIVTLREPAG RAISSWEFKN
EYNPKKGRRE ESRSLAKTIE DGGRRAMKLH ACLALAKSKA VSPRDRDLKL CNPRKFLEVP
LYVSHVGKSM YALQLERWFD LFGRENFKVV FTDDMAVDPV GVLEDVLHFL GLELTSEDES
KGLPDMKGWK KITGMAYNKT KSKKKDELGD QVTDEVKEGL RKFFEPHNEA LEEILGQPLP
EAWGS
//
