ID D8LS23_ECTSI Unreviewed; 346 AA.
AC D8LS23;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=HNH domain-containing protein {ECO:0000259|Pfam:PF01844};
GN ORFNames=Esi_0007_0089 {ECO:0000313|EMBL:CBN73807.1};
OS Ectocarpus siliculosus (Brown alga) (Conferva siliculosa).
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; PX clade; Phaeophyceae;
OC Ectocarpales; Ectocarpaceae; Ectocarpus.
OX NCBI_TaxID=2880 {ECO:0000313|EMBL:CBN73807.1, ECO:0000313|Proteomes:UP000002630};
RN [1] {ECO:0000313|EMBL:CBN73807.1, ECO:0000313|Proteomes:UP000002630}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ec32 / CCAP1310/4 {ECO:0000313|Proteomes:UP000002630};
RX PubMed=20520714; DOI=10.1038/nature09016;
RA Cock J.M., Sterck L., Rouze P., Scornet D., Allen A.E., Amoutzias G.,
RA Anthouard V., Artiguenave F., Aury J.M., Badger J.H., Beszteri B.,
RA Billiau K., Bonnet E., Bothwell J.H., Bowler C., Boyen C., Brownlee C.,
RA Carrano C.J., Charrier B., Cho G.Y., Coelho S.M., Collen J., Corre E.,
RA Da Silva C., Delage L., Delaroque N., Dittami S.M., Doulbeau S., Elias M.,
RA Farnham G., Gachon C.M., Gschloessl B., Heesch S., Jabbari K., Jubin C.,
RA Kawai H., Kimura K., Kloareg B., Kupper F.C., Lang D., Le Bail A.,
RA Leblanc C., Lerouge P., Lohr M., Lopez P.J., Martens C., Maumus F.,
RA Michel G., Miranda-Saavedra D., Morales J., Moreau H., Motomura T.,
RA Nagasato C., Napoli C.A., Nelson D.R., Nyvall-Collen P., Peters A.F.,
RA Pommier C., Potin P., Poulain J., Quesneville H., Read B., Rensing S.A.,
RA Ritter A., Rousvoal S., Samanta M., Samson G., Schroeder D.C., Segurens B.,
RA Strittmatter M., Tonon T., Tregear J.W., Valentin K., von Dassow P.,
RA Yamagishi T., Van de Peer Y., Wincker P.;
RT "The Ectocarpus genome and the independent evolution of multicellularity in
RT brown algae.";
RL Nature 465:617-621(2010).
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DR EMBL; FN648926; CBN73807.1; -; Genomic_DNA.
DR AlphaFoldDB; D8LS23; -.
DR STRING; 2880.D8LS23; -.
DR EnsemblProtists; CBN73807; CBN73807; Esi_0007_0089.
DR eggNOG; KOG1000; Eukaryota.
DR InParanoid; D8LS23; -.
DR OrthoDB; 318617at2759; -.
DR Proteomes; UP000002630; Chromosome LG06.
DR GO; GO:0004519; F:endonuclease activity; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd00085; HNHc; 1.
DR Gene3D; 1.10.30.50; -; 1.
DR InterPro; IPR002711; HNH.
DR InterPro; IPR003615; HNH_nuc.
DR PANTHER; PTHR45766; DNA ANNEALING HELICASE AND ENDONUCLEASE ZRANB3 FAMILY MEMBER; 1.
DR PANTHER; PTHR45766:SF5; SNF2 DOMAIN-CONTAINING PROTEIN _ HELICASE DOMAIN-CONTAINING PROTEIN _ HNH ENDONUCLEASE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF01844; HNH; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002630}.
FT DOMAIN 260..295
FT /note="HNH"
FT /evidence="ECO:0000259|Pfam:PF01844"
FT REGION 116..137
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 346 AA; 37341 MW; 73DC22FA492BFCEB CRC64;
MRAFVAPTIL FSIVRRSCRG LAVGASAAGR LPGCRTTASS CTVKRAASTE TAATSLSGWP
RRLDPDNCKV ADIRQQLRRR GYTPPRDRQT KAALLEELRG LVRAEGFAPP DAVVRNDTVT
REGPEGSEGD GKAQQRWNPE AGWVDRATME RGERGYPLCR FCNEEVPSAR RTFCSDACVH
EHRIRTQGSY VRKCLLVRDG GQCAECGVDA AGLYKRARAA WICEGSVVVK REAVALEMVG
TPFEGKMPTK GMTRRPTQGK FWHADHIVPV VRGGGQCSLK NYRTLCVPCH AAATKRLAGE
RAAERARAAA AAAAAAAAAV ASDSVAGTGA VVVKKKRGRP RKIVDR
//
