ID D8M2H3_BLAHO Unreviewed; 295 AA.
AC D8M2H3;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=Mitoferrin (Mrs3/Mrs4) {ECO:0000313|EMBL:CBK22262.2};
GN ORFNames=GSBLH_T00002317001 {ECO:0000313|EMBL:CBK22262.2};
OS Blastocystis hominis.
OC Eukaryota; Sar; Stramenopiles; Bigyra; Opalozoa; Opalinata; Blastocystidae;
OC Blastocystis.
OX NCBI_TaxID=12968 {ECO:0000313|EMBL:CBK22262.2};
RN [1] {ECO:0000313|EMBL:CBK22262.2}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Singapore isolate B {ECO:0000313|EMBL:CBK22262.2};
RA Wincker P.;
RT "Sequencing and annotation of the Blastocystis hominis genome.";
RL Submitted (FEB-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the mitochondrial carrier (TC 2.A.29) family.
CC {ECO:0000256|ARBA:ARBA00006375, ECO:0000256|RuleBase:RU000488}.
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DR EMBL; FN668649; CBK22262.2; -; Genomic_DNA.
DR RefSeq; XP_012896310.1; XM_013040856.1.
DR AlphaFoldDB; D8M2H3; -.
DR EnsemblProtists; CBK22262; CBK22262; GSBLH_T00002317001.
DR GeneID; 24919495; -.
DR InParanoid; D8M2H3; -.
DR OMA; THCTAGA; -.
DR OrthoDB; 5481380at2759; -.
DR Proteomes; UP000008312; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-KW.
DR GO; GO:0048250; P:iron import into the mitochondrion; IEA:UniProt.
DR Gene3D; 1.50.40.10; Mitochondrial carrier domain; 2.
DR InterPro; IPR018108; Mitochondrial_sb/sol_carrier.
DR InterPro; IPR023395; Mt_carrier_dom_sf.
DR PANTHER; PTHR45758:SF4; MITOFERRIN-1; 1.
DR PANTHER; PTHR45758; MITOFERRIN-1-RELATED; 1.
DR Pfam; PF00153; Mito_carr; 3.
DR SUPFAM; SSF103506; Mitochondrial carrier; 1.
DR PROSITE; PS50920; SOLCAR; 3.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PROSITE-
KW ProRule:PRU00282}; Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Reference proteome {ECO:0000313|Proteomes:UP000008312};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|PROSITE-
KW ProRule:PRU00282};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU000488}.
FT TRANSMEM 61..81
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 166..187
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 207..228
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REPEAT 15..90
FT /note="Solcar"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
FT REPEAT 113..195
FT /note="Solcar"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
FT REPEAT 202..293
FT /note="Solcar"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
SQ SEQUENCE 295 AA; 32701 MW; E9C8AAA8DF9AF3F1 CRC64;
MSDNYDWEEW NESATTFRQH VLAGCVAGVS EHIVFFPIDT VRVCAIPTFD HHSIRSEGLR
VLWRGMSMTI TACIPAHALY FSIYEYTKRK LGGNDNKHIL FASFSNSFSF TSLHANASAI
GGALASVAHD AVMTPLDVVK QRMQLGLYSS PMTALRSIIR YEGFRALYSS YFTTILMNVP
NAAVLVVTND WMKSILNPSG KQNFSAFLVS GLVAGSLSGF VTCPLDVIKT RIQTQTTGAD
GVLRRYTGFW QTLKLLVKEE GVRSLFMGVS TRIMQQAPAA ALSWTVYETV KRLLV
//
