ID D8M450_BLAHO Unreviewed; 188 AA.
AC D8M450;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE RecName: Full=Nuclear cap-binding protein subunit 2 {ECO:0000256|RuleBase:RU364036};
DE AltName: Full=20 kDa nuclear cap-binding protein {ECO:0000256|RuleBase:RU364036};
GN ORFNames=GSBLH_T00002427001 {ECO:0000313|EMBL:CBK22839.2};
OS Blastocystis hominis.
OC Eukaryota; Sar; Stramenopiles; Bigyra; Opalozoa; Opalinata; Blastocystidae;
OC Blastocystis.
OX NCBI_TaxID=12968 {ECO:0000313|EMBL:CBK22839.2};
RN [1] {ECO:0000313|EMBL:CBK22839.2}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Singapore isolate B {ECO:0000313|EMBL:CBK22839.2};
RA Wincker P.;
RT "Sequencing and annotation of the Blastocystis hominis genome.";
RL Submitted (FEB-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|RuleBase:RU364036}.
CC -!- SIMILARITY: Belongs to the RRM NCBP2 family.
CC {ECO:0000256|ARBA:ARBA00010725, ECO:0000256|RuleBase:RU364036}.
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DR EMBL; FN668651; CBK22839.2; -; Genomic_DNA.
DR RefSeq; XP_012896887.1; XM_013041433.1.
DR AlphaFoldDB; D8M450; -.
DR EnsemblProtists; CBK22839; CBK22839; GSBLH_T00002427001.
DR GeneID; 24919597; -.
DR InParanoid; D8M450; -.
DR OMA; WRDELRT; -.
DR OrthoDB; 5880at2759; -.
DR Proteomes; UP000008312; Unassembled WGS sequence.
DR GO; GO:0005846; C:nuclear cap binding complex; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0000339; F:RNA cap binding; IEA:InterPro.
DR GO; GO:0045292; P:mRNA cis splicing, via spliceosome; IEA:InterPro.
DR CDD; cd12240; RRM_NCBP2; 1.
DR Gene3D; 3.30.70.330; -; 1.
DR InterPro; IPR027157; NCBP2.
DR InterPro; IPR034148; NCBP2_RRM.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR PANTHER; PTHR18847; 20 KD NUCLEAR CAP BINDING PROTEIN; 1.
DR PANTHER; PTHR18847:SF0; NUCLEAR CAP-BINDING PROTEIN SUBUNIT 2; 1.
DR Pfam; PF00076; RRM_1; 1.
DR SMART; SM00360; RRM; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR PROSITE; PS50102; RRM; 1.
PE 3: Inferred from homology;
KW mRNA processing {ECO:0000256|ARBA:ARBA00022664,
KW ECO:0000256|RuleBase:RU364036};
KW mRNA splicing {ECO:0000256|ARBA:ARBA00023187,
KW ECO:0000256|RuleBase:RU364036};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU364036};
KW Reference proteome {ECO:0000313|Proteomes:UP000008312};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00176,
KW ECO:0000256|RuleBase:RU364036}.
FT DOMAIN 34..112
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 143..188
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 143..166
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 188 AA; 21791 MW; 2AFE0BC0C0653930 CRC64;
MATLYNVPIR KEPKFYRDYF SSKEDQLNAL KSSSTIYVGN LNFSTTEERI FAAFSCCGPI
DKVIMGINRR TLAPCGFCFV IFYTHEAAQN AVDFMSGLKI DGRNIRVEMD WGYSDGRQYG
RAVDGGQIRH YVKDIITKGQ NLDKKQDNHG YRDNRKRDRD GGYNSRYNDS RSRYGNDSGY
DYKRHKSY
//
