ID D8MAN6_BLAHO Unreviewed; 536 AA.
AC D8MAN6;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:CBK25125.2};
GN ORFNames=GSBLH_T00004758001 {ECO:0000313|EMBL:CBK25125.2};
OS Blastocystis hominis.
OC Eukaryota; Sar; Stramenopiles; Bigyra; Opalozoa; Opalinata; Blastocystidae;
OC Blastocystis.
OX NCBI_TaxID=12968 {ECO:0000313|EMBL:CBK25125.2};
RN [1] {ECO:0000313|EMBL:CBK25125.2}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Singapore isolate B {ECO:0000313|EMBL:CBK25125.2};
RA Wincker P.;
RT "Sequencing and annotation of the Blastocystis hominis genome.";
RL Submitted (FEB-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Protein modification; protein glycosylation.
CC {ECO:0000256|ARBA:ARBA00004922}.
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DR EMBL; FN668690; CBK25125.2; -; Genomic_DNA.
DR RefSeq; XP_012899173.1; XM_013043719.1.
DR AlphaFoldDB; D8MAN6; -.
DR EnsemblProtists; CBK25125; CBK25125; GSBLH_T00004758001.
DR GeneID; 24921764; -.
DR InParanoid; D8MAN6; -.
DR OMA; CKLIIDW; -.
DR OrthoDB; 1219598at2759; -.
DR Proteomes; UP000008312; Unassembled WGS sequence.
DR GO; GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000030; F:mannosyltransferase activity; IEA:InterPro.
DR Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR InterPro; IPR026051; ALG1-like.
DR InterPro; IPR001296; Glyco_trans_1.
DR InterPro; IPR028098; Glyco_trans_4-like_N.
DR PANTHER; PTHR13036; BETA1,4 MANNOSYLTRANSFERASE; 1.
DR PANTHER; PTHR13036:SF0; CHITOBIOSYLDIPHOSPHODOLICHOL BETA-MANNOSYLTRANSFERASE; 1.
DR Pfam; PF13579; Glyco_trans_4_4; 1.
DR Pfam; PF00534; Glycos_transf_1; 1.
DR SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
PE 4: Predicted;
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008312};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 70..91
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 98..119
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 24..182
FT /note="Glycosyltransferase subfamily 4-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF13579"
FT DOMAIN 238..390
FT /note="Glycosyl transferase family 1"
FT /evidence="ECO:0000259|Pfam:PF00534"
SQ SEQUENCE 536 AA; 60984 MW; C32818829A5CBD13 CRC64;
MTTGTVVVLG DIGRSPRMQY HCMSLASEGV DVNIVAYDGK KCCEEVESNK KITKYLIDSN
LFSKLPRSLF LLYAPFKVLF QIFQLFYLLL FKTPKPDFYL VQNPPSIPTL FVVWLVARLQ
KAKFFIDWHN FGYFLFVTIV NQATRFFISK WIEHFFGQRS DGNLCVTRAM KNWLRSEWNI
EASVLYDRAP TFFHPTSLAD RHALFQRILP QLGFPCTAQQ TLFTEMDKNG EVCLRANRPA
LLVSSTSWTE DEDFHILLNA LQTLDQTYEV TEGLKVVCVI TGTGPLKEYY EQLVEEMKLQ
HVWIKTIWLE YSDYPLLLGA ADLGVCLHTS SSGLDLPMKV VDMFGCGLPV CAAGFNCIAE
LVVDEQNGLV FESEMQLEEK LQALLKDFPR NQERLTELRR GVEESQSVCW EENWKKCAKP
VILCCLVCCE QTEKGTVRGL RPKQANLDLP AASAWLQVPR AVSLVRCPCP SSEFFLRWLS
ALDAEQREAH GDGFAHEEIH RGVATERHCA ARHASLVSGN RTVFVVEFNR IGIAVS
//
