ID D8MNL7_ERWBE Unreviewed; 679 AA.
AC D8MNL7;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE RecName: Full=beta-galactosidase {ECO:0000256|ARBA:ARBA00012756};
DE EC=3.2.1.23 {ECO:0000256|ARBA:ARBA00012756};
GN OrderedLocusNames=EbC_08930 {ECO:0000313|EMBL:CAX58424.1};
OS Erwinia billingiae (strain Eb661).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Erwiniaceae; Erwinia.
OX NCBI_TaxID=634500 {ECO:0000313|Proteomes:UP000008793};
RN [1] {ECO:0000313|EMBL:CAX58424.1, ECO:0000313|Proteomes:UP000008793}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Eb661 {ECO:0000313|EMBL:CAX58424.1,
RC ECO:0000313|Proteomes:UP000008793};
RX PubMed=20565991; DOI=10.1186/1471-2164-11-393;
RA Kube M., Migdoll A.M., Gehring I., Heitmann K., Mayer Y., Kuhl H.,
RA Knaust F., Geider K., Reinhardt R.;
RT "Genome comparison of the epiphytic bacteria Erwinia billingiae and E.
RT tasmaniensis with the pear pathogen E. pyrifoliae.";
RL BMC Genomics 11:393-393(2010).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal non-reducing beta-D-galactose residues
CC in beta-D-galactosides.; EC=3.2.1.23;
CC Evidence={ECO:0000256|ARBA:ARBA00001412};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 42 family.
CC {ECO:0000256|ARBA:ARBA00005940}.
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DR EMBL; FP236843; CAX58424.1; -; Genomic_DNA.
DR RefSeq; WP_013200927.1; NC_014306.1.
DR AlphaFoldDB; D8MNL7; -.
DR STRING; 634500.EbC_08930; -.
DR CAZy; GH42; Glycoside Hydrolase Family 42.
DR KEGG; ebi:EbC_08930; -.
DR eggNOG; COG1874; Bacteria.
DR HOGENOM; CLU_012430_2_0_6; -.
DR Proteomes; UP000008793; Chromosome.
DR GO; GO:0009341; C:beta-galactosidase complex; IEA:InterPro.
DR GO; GO:0004565; F:beta-galactosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd03143; A4_beta-galactosidase_middle_domain; 1.
DR Gene3D; 3.40.50.880; -; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR013738; Beta_galactosidase_Trimer.
DR InterPro; IPR029062; Class_I_gatase-like.
DR InterPro; IPR003476; Glyco_hydro_42.
DR InterPro; IPR013529; Glyco_hydro_42_N.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR36447; BETA-GALACTOSIDASE GANA; 1.
DR PANTHER; PTHR36447:SF2; BETA-GALACTOSIDASE YESZ; 1.
DR Pfam; PF02449; Glyco_hydro_42; 1.
DR Pfam; PF08532; Glyco_hydro_42M; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF52317; Class I glutamine amidotransferase-like; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000313|EMBL:CAX58424.1};
KW Hydrolase {ECO:0000313|EMBL:CAX58424.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000008793}.
FT DOMAIN 10..377
FT /note="Glycoside hydrolase family 42 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02449"
FT DOMAIN 417..601
FT /note="Beta-galactosidase trimerisation"
FT /evidence="ECO:0000259|Pfam:PF08532"
SQ SEQUENCE 679 AA; 77148 MW; AD9354F1844919C0 CRC64;
MDKIWFGTAY YREYMPEERL EKDIAMMKAA GINYVRIAES TWSTFEPQEG EFDFTSVITV
LDQMQANDIS VIIGTPTYAI PGWLAKKYPE VMAVTPQGLN KYGPRQKMDI TSPVYRYYSE
RIIRKLLTAT ASHPAVIGFQ VDNETKYYET SGPAVQIAFV KYLRKKFNDD LPALNQAFGL
DYWSNRVDAW EDFPSVQGTI NASLGAEFQA FQRQLVIDFL RWQVDLVGEY KSADRFVTHN
FDFDWRNWSF GLRSEVDHFA ASEVVDITGV DVYHPGQSRL TGAEIAFTGD IARTTKDKNY
FVLETQAQAF KDWTPYPGQL RLQAFSHIAN GASLVGYWHW HSIHNSWETY WKGLLSHDLL
PNPVYDEACD IGKTLQRLTP ELSGLSKSNR VAMLVSNRGL TAIDWHPWRG HQFGGDKNHQ
YNDLFRSWYD ALYRQNIEMD ILDADDPRIE RYDVLIVPLL YAASDALLQR LNAFVGQGGH
IIYSFKSGFA NQDLKVRTAI QPGIISEACG VTYQLFVEPD EVQMSTETFA LTEETGQVTD
WMELLEPVSS QTEILARYQH PQWGKYAAIT RNQFGKGTAT YIGCNLSSAG MEQVFSTLFS
TPALSALRSE VSFPLIIRRA QSKAQKDLCF IFNYSQTPQQ LRNPLGQATS LIDNRQVEPG
ETLEIAGWDF VILSGGEAV
//
