ID D8PEV2_9BACT Unreviewed; 187 AA.
AC D8PEV2;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=Anthranilate synthase, component II {ECO:0000313|EMBL:CBK41761.1};
DE EC=4.1.3.27 {ECO:0000313|EMBL:CBK41761.1};
GN Name=trpG {ECO:0000313|EMBL:CBK41761.1};
GN ORFNames=NIDE2041 {ECO:0000313|EMBL:CBK41761.1};
OS Nitrospira defluvii.
OC Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
OC Nitrospira.
OX NCBI_TaxID=330214 {ECO:0000313|EMBL:CBK41761.1, ECO:0000313|Proteomes:UP000001660};
RN [1] {ECO:0000313|EMBL:CBK41761.1, ECO:0000313|Proteomes:UP000001660}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20624973; DOI=10.1073/pnas.1003860107;
RA Lucker S., Wagner M., Maixner F., Pelletier E., Koch H., Vacherie B.,
RA Rattei T., Sinninghe Damste J., Spieck E., Le Paslier D., Daims H.;
RT "A Nitrospira metagenome illuminates the physiology and evolution of
RT globally important nitrite-oxidizing bacteria.";
RL Proc. Natl. Acad. Sci. U.S.A. 0:13479-13484(2010).
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DR EMBL; FP929003; CBK41761.1; -; Genomic_DNA.
DR AlphaFoldDB; D8PEV2; -.
DR STRING; 330214.NIDE2041; -.
DR MEROPS; C26.955; -.
DR KEGG; nde:NIDE2041; -.
DR eggNOG; COG0512; Bacteria.
DR HOGENOM; CLU_014340_1_2_0; -.
DR OrthoDB; 9804328at2; -.
DR Proteomes; UP000001660; Chromosome.
DR GO; GO:0004049; F:anthranilate synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0008652; P:amino acid biosynthetic process; IEA:UniProt.
DR GO; GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:UniProt.
DR GO; GO:0044271; P:cellular nitrogen compound biosynthetic process; IEA:UniProt.
DR GO; GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-UniRule.
DR GO; GO:0018130; P:heterocycle biosynthetic process; IEA:UniProt.
DR CDD; cd01743; GATase1_Anthranilate_Synthase; 1.
DR Gene3D; 3.40.50.880; -; 1.
DR InterPro; IPR029062; Class_I_gatase-like.
DR InterPro; IPR017926; GATASE.
DR InterPro; IPR006221; TrpG/PapA_dom.
DR NCBIfam; TIGR00566; trpG_papA; 1.
DR PANTHER; PTHR43418:SF4; MULTIFUNCTIONAL TRYPTOPHAN BIOSYNTHESIS PROTEIN; 1.
DR PANTHER; PTHR43418; MULTIFUNCTIONAL TRYPTOPHAN BIOSYNTHESIS PROTEIN-RELATED; 1.
DR Pfam; PF00117; GATase; 1.
DR PRINTS; PR00097; ANTSNTHASEII.
DR PRINTS; PR00099; CPSGATASE.
DR PRINTS; PR00096; GATASE.
DR SUPFAM; SSF52317; Class I glutamine amidotransferase-like; 1.
DR PROSITE; PS51273; GATASE_TYPE_1; 1.
PE 4: Predicted;
KW Glutamine amidotransferase {ECO:0000256|PROSITE-ProRule:PRU00605};
KW Lyase {ECO:0000313|EMBL:CBK41761.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001660}.
FT DOMAIN 3..185
FT /note="Glutamine amidotransferase"
FT /evidence="ECO:0000259|Pfam:PF00117"
FT ACT_SITE 79
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00605"
FT ACT_SITE 168
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00605"
FT ACT_SITE 170
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00605"
SQ SEQUENCE 187 AA; 20993 MW; 3B86ACBEA160C2D0 CRC64;
MLLMIDNYDS FTYNLVQYFG ELGEDVVVYR NDKISIREIE ALKPRRLVIS PGPCTPNEAG
ISVEAIRHFG GKLPLLGVCL GHQSLAVAFG GEVIRAERLM HGKTSMVRHD GRTIFRNLPN
PFEATRYHSL IVNRKNLPDC FEISAETAEG EIMGMRHKTL GIEGVQFHPE SILTTAGKEL
LRNFLKL
//
