ID   D8PN39_SCHCM            Unreviewed;       567 AA.
AC   D8PN39;
DT   05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2010, sequence version 1.
DT   27-MAR-2024, entry version 45.
DE   RecName: Full=Nucleotidyl transferase domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=SCHCODRAFT_80649 {ECO:0000313|EMBL:EFJ03545.1};
OS   Schizophyllum commune (strain H4-8 / FGSC 9210) (Split gill fungus).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC   Agaricomycetidae; Agaricales; Schizophyllaceae; Schizophyllum.
OX   NCBI_TaxID=578458 {ECO:0000313|Proteomes:UP000007431};
RN   [1] {ECO:0000313|EMBL:EFJ03545.1, ECO:0000313|Proteomes:UP000007431}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=H4-8 / FGSC 9210 {ECO:0000313|Proteomes:UP000007431};
RX   PubMed=20622885; DOI=10.1038/nbt.1643;
RA   Ohm R.A., de Jong J.F., Lugones L.G., Aerts A., Kothe E., Stajich J.E.,
RA   de Vries R.P., Record E., Levasseur A., Baker S.E., Bartholomew K.A.,
RA   Coutinho P.M., Erdmann S., Fowler T.J., Gathman A.C., Lombard V.,
RA   Henrissat B., Knabe N., Kuees U., Lilly W.W., Lindquist E., Lucas S.,
RA   Magnuson J.K., Piumi F., Raudaskoski M., Salamov A., Schmutz J.,
RA   Schwarze F.W.M.R., vanKuyk P.A., Horton J.S., Grigoriev I.V.,
RA   Woesten H.A.B.;
RT   "Genome sequence of the model mushroom Schizophyllum commune.";
RL   Nat. Biotechnol. 28:957-963(2010).
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DR   EMBL; GL377302; EFJ03545.1; -; Genomic_DNA.
DR   RefSeq; XP_003038447.1; XM_003038401.1.
DR   AlphaFoldDB; D8PN39; -.
DR   STRING; 578458.D8PN39; -.
DR   GeneID; 9597546; -.
DR   KEGG; scm:SCHCO_02567361; -.
DR   VEuPathDB; FungiDB:SCHCODRAFT_02567361; -.
DR   eggNOG; ENOG502S2CD; Eukaryota.
DR   HOGENOM; CLU_035527_0_1_1; -.
DR   InParanoid; D8PN39; -.
DR   OMA; WSDLGNF; -.
DR   OrthoDB; 20301at2759; -.
DR   Proteomes; UP000007431; Unassembled WGS sequence.
DR   GO; GO:0004475; F:mannose-1-phosphate guanylyltransferase (GTP) activity; IEA:InterPro.
DR   GO; GO:0044271; P:cellular nitrogen compound biosynthetic process; IEA:UniProt.
DR   GO; GO:0005976; P:polysaccharide metabolic process; IEA:InterPro.
DR   CDD; cd02509; GDP-M1P_Guanylyltransferase; 1.
DR   InterPro; IPR049577; GMPP_N.
DR   InterPro; IPR001538; Man6P_isomerase-2_C.
DR   InterPro; IPR005835; NTP_transferase_dom.
DR   InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR   PANTHER; PTHR46390; MANNOSE-1-PHOSPHATE GUANYLYLTRANSFERASE; 1.
DR   PANTHER; PTHR46390:SF1; MANNOSE-1-PHOSPHATE GUANYLYLTRANSFERASE; 1.
DR   Pfam; PF01050; MannoseP_isomer; 1.
DR   Pfam; PF00483; NTP_transferase; 1.
DR   SUPFAM; SSF159283; Guanosine diphospho-D-mannose pyrophosphorylase/mannose-6-phosphate isomerase linker domain; 1.
DR   SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007431};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          181..461
FT                   /note="Nucleotidyl transferase"
FT                   /evidence="ECO:0000259|Pfam:PF00483"
FT   DOMAIN          500..552
FT                   /note="Mannose-6-phosphate isomerase type II C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF01050"
FT   REGION          106..142
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          71..105
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        106..133
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   567 AA;  61100 MW;  6D1DD1C73FF7AD38 CRC64;
     MRTRQKYTAR RHVSNVLIQP IIYTLPPTST VLLTSHPPRK IMNANLGPSL FSNAAPSEPA
     APVPLGIESM FQQIMQAVQK SNAEISDLKN ECAELRLANA SLERQIREGQ NGQSHTPGTL
     TPRRSSPQLR PKSPFLSASA IPPTSVPPLP TSLAYHPSPL GDNGLSAYPL DARDIPGFYV
     VIPAGGAGTR LWPLSRENHP KFLLDLTLSG RSLIQATWDR LIPLASPERT TVVAGPAHVS
     AISSQLPDLK PENVFCEPSA KDSMAAIGLA AAVLAKRDPD AVIGSFAADH MISGDDAFLA
     AVAEAVQVAK RDYLVTIGIA PVAPSTGFGY IRLGDRLEFN NAPNARLVKD FKEKPDARTA
     AAYLATGNYR WNAGMFVTKA SFLMQLVREH KPTMAASLEK IAEVWDEPSK RDSVLSEIWP
     TLEKIPIDNA IAEPAAREGK VAVVPATFGW DDVGDFSSVA DRLPSEYNQP RILGDGHLVV
     TEQVAGGIIV PGSGRLVTCL GVDDLVIVDM PDALLVTTRA RSQEVKNIVK KTKSAGCAPA
     SVTHVIEEHR HWKYIATGSI SLREVHT
//