ID D8PRG4_SCHCM Unreviewed; 1084 AA.
AC D8PRG4;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE RecName: Full=Carrier domain-containing protein {ECO:0000259|PROSITE:PS50075};
GN ORFNames=SCHCODRAFT_47390 {ECO:0000313|EMBL:EFJ01785.1};
OS Schizophyllum commune (strain H4-8 / FGSC 9210) (Split gill fungus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Schizophyllaceae; Schizophyllum.
OX NCBI_TaxID=578458 {ECO:0000313|Proteomes:UP000007431};
RN [1] {ECO:0000313|EMBL:EFJ01785.1, ECO:0000313|Proteomes:UP000007431}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H4-8 / FGSC 9210 {ECO:0000313|Proteomes:UP000007431};
RX PubMed=20622885; DOI=10.1038/nbt.1643;
RA Ohm R.A., de Jong J.F., Lugones L.G., Aerts A., Kothe E., Stajich J.E.,
RA de Vries R.P., Record E., Levasseur A., Baker S.E., Bartholomew K.A.,
RA Coutinho P.M., Erdmann S., Fowler T.J., Gathman A.C., Lombard V.,
RA Henrissat B., Knabe N., Kuees U., Lilly W.W., Lindquist E., Lucas S.,
RA Magnuson J.K., Piumi F., Raudaskoski M., Salamov A., Schmutz J.,
RA Schwarze F.W.M.R., vanKuyk P.A., Horton J.S., Grigoriev I.V.,
RA Woesten H.A.B.;
RT "Genome sequence of the model mushroom Schizophyllum commune.";
RL Nat. Biotechnol. 28:957-963(2010).
CC -!- PATHWAY: Siderophore biosynthesis. {ECO:0000256|ARBA:ARBA00004924}.
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DR EMBL; GL377302; EFJ01785.1; -; Genomic_DNA.
DR RefSeq; XP_003036687.1; XM_003036641.1.
DR AlphaFoldDB; D8PRG4; -.
DR STRING; 578458.D8PRG4; -.
DR GeneID; 9597803; -.
DR KEGG; scm:SCHCO_01166049; -.
DR VEuPathDB; FungiDB:SCHCODRAFT_01166049; -.
DR eggNOG; KOG1178; Eukaryota.
DR HOGENOM; CLU_000022_2_4_1; -.
DR InParanoid; D8PRG4; -.
DR OMA; YGRFHRS; -.
DR OrthoDB; 1636312at2759; -.
DR Proteomes; UP000007431; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR GO; GO:0043604; P:amide biosynthetic process; IEA:UniProt.
DR GO; GO:1901566; P:organonitrogen compound biosynthetic process; IEA:UniProt.
DR CDD; cd19531; LCL_NRPS-like; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.980; -; 2.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 1.
DR Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR001242; Condensatn.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR PANTHER; PTHR45527:SF16; NONRIBOSOMAL PEPTIDE SYNTHETASE ASQK; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF00668; Condensation; 1.
DR Pfam; PF00550; PP-binding; 1.
DR SMART; SM00823; PKS_PP; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 2.
DR SUPFAM; SSF47336; ACP-like; 1.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 2.
DR PROSITE; PS50075; CARRIER; 1.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 1.
PE 4: Predicted;
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000007431}.
FT DOMAIN 227..304
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
SQ SEQUENCE 1084 AA; 120561 MW; F54BEE0011546F62 CRC64;
MYVLDSHQRL VPPGMIGTMY IASEVLARGY TEERLNEAFY PASKISKAWG LTPSPEDRRR
FFRSSDQARW LCATGQLEYM GRNDTEVNIR GQRVDLAGVD HALRKSIEIL DAVTVIQHDP
QGAALLVSFV VPKFDAKVNK AGDLAGAEQS PTDVWADVGD SIEFERKLKD AVSAILPSFM
IPSFIVPLSQ FPQTITGKID RKALTSWTHL VDYARDADGS TTVGGDESTS AVEEIMIEIF
KEVLQRKQVR ADNSFFHLGG HSLLATQVIS RIRKALGVDD RLTVRALFDA PTAGALAQLV
ESLQDQDCKE SNVTPAIAIS YQPIERLRAQ DSYTLSYAQE RLYFLDLLHP GQTGYIIPHV
LRIGGTLDIQ ALRAAFHRLR QRHEMLRVTY EDNHGVIVQR IHACDEQELL VVDLTLDAKP
DDTLRKMLQA DNDASLDLHK DLPLRFKLYR LGPDTHVLWM ALHHLSTDAW SDRVIQRELG
QLYAAYHTGL PANLPDLPIT YMDYAAWQRQ PDQSVRQEEQ LKYWVDTLQG SVPAEFPTDF
VRPSALSARA GLERIDILGE DATALERFAA SMNSTPFIVL LSALRTLHYR LTGVEDATLG
NPIANRNRME LEGVVGFFVN TQSMRIPLEG KMSFRQLCEN VRTTAAAAYE AQDIAFERVV
HELQPARDLS RNPIVQVMIA VHPEEDSHLG DDEGSALEVQ QVNVEPVTRF DLEFHFVKMR
NGEGYDGRLL YSRDLYTPAS AARLSEQFKA ILRQAIEAEE KSVGADMALE EFVFPDVVNS
LVQFGLLDDT SCPYPSDKGL GELFRMSALA HADCVAVKDA TRVVSYKELN ALSDRVARHL
LSLRLAPETF VGLLCARSVH YIAAIIGILK AGLAYLPLDP QLPRNRLVTL LNDIPRHSVV
YHDASLAELD TTGMGHDFVD VHAASVVNIN GRNLAYAMYT SGSTGKPKAV LIEQRSIARL
AYSQSVVEPR RGQVWAHISN TAFDSSTWEI WAPLLNGGTV VCFDKMIVLD FDLLKEAFKV
HGVDVAFLTT ALAAKCLHET PSIIKNLEIL ATGGETCDPH DLTAMSEMIR GCVAHVYGPT
ESTT
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