ID D8Q4K9_SCHCM Unreviewed; 755 AA.
AC D8Q4K9;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE RecName: Full=PABS domain-containing protein {ECO:0000259|PROSITE:PS51006};
GN ORFNames=SCHCODRAFT_257151 {ECO:0000313|EMBL:EFI97250.1};
OS Schizophyllum commune (strain H4-8 / FGSC 9210) (Split gill fungus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Schizophyllaceae; Schizophyllum.
OX NCBI_TaxID=578458 {ECO:0000313|Proteomes:UP000007431};
RN [1] {ECO:0000313|EMBL:EFI97250.1, ECO:0000313|Proteomes:UP000007431}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H4-8 / FGSC 9210 {ECO:0000313|Proteomes:UP000007431};
RX PubMed=20622885; DOI=10.1038/nbt.1643;
RA Ohm R.A., de Jong J.F., Lugones L.G., Aerts A., Kothe E., Stajich J.E.,
RA de Vries R.P., Record E., Levasseur A., Baker S.E., Bartholomew K.A.,
RA Coutinho P.M., Erdmann S., Fowler T.J., Gathman A.C., Lombard V.,
RA Henrissat B., Knabe N., Kuees U., Lilly W.W., Lindquist E., Lucas S.,
RA Magnuson J.K., Piumi F., Raudaskoski M., Salamov A., Schmutz J.,
RA Schwarze F.W.M.R., vanKuyk P.A., Horton J.S., Grigoriev I.V.,
RA Woesten H.A.B.;
RT "Genome sequence of the model mushroom Schizophyllum commune.";
RL Nat. Biotechnol. 28:957-963(2010).
CC -!- SIMILARITY: Belongs to the spermidine/spermine synthase family.
CC {ECO:0000256|ARBA:ARBA00007867, ECO:0000256|RuleBase:RU003836}.
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DR EMBL; GL377306; EFI97250.1; -; Genomic_DNA.
DR RefSeq; XP_003032153.1; XM_003032107.1.
DR AlphaFoldDB; D8Q4K9; -.
DR STRING; 578458.D8Q4K9; -.
DR VEuPathDB; FungiDB:SCHCODRAFT_02542524; -.
DR eggNOG; KOG0172; Eukaryota.
DR eggNOG; KOG1562; Eukaryota.
DR HOGENOM; CLU_016207_2_0_1; -.
DR InParanoid; D8Q4K9; -.
DR OMA; TEQCLIT; -.
DR OrthoDB; 2184985at2759; -.
DR Proteomes; UP000007431; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0009085; P:lysine biosynthetic process; IEA:UniProtKB-KW.
DR GO; GO:0006596; P:polyamine biosynthetic process; IEA:UniProtKB-UniRule.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 1.10.1870.10; Domain 3, Saccharopine reductase; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 2.30.140.10; Spermidine synthase, tetramerisation domain; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR HAMAP; MF_00198; Spermidine_synth; 1.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR030374; PABS.
DR InterPro; IPR030373; PABS_CS.
DR InterPro; IPR032095; Sacchrp_dh-like_C.
DR InterPro; IPR005097; Sacchrp_dh_NADP.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR001045; Spermi_synthase.
DR InterPro; IPR035246; Spermidine_synt_N.
DR InterPro; IPR037163; Spermidine_synt_N_sf.
DR NCBIfam; TIGR00417; speE; 1.
DR PANTHER; PTHR11133:SF25; ALPHA-AMINOADIPIC SEMIALDEHYDE SYNTHASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11133; SACCHAROPINE DEHYDROGENASE; 1.
DR Pfam; PF16653; Sacchrp_dh_C; 1.
DR Pfam; PF03435; Sacchrp_dh_NADP; 1.
DR Pfam; PF17284; Spermine_synt_N; 1.
DR Pfam; PF01564; Spermine_synth; 1.
DR SUPFAM; SSF55347; Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS01330; PABS_1; 1.
DR PROSITE; PS51006; PABS_2; 1.
PE 3: Inferred from homology;
KW Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00023154};
KW Lysine biosynthesis {ECO:0000256|ARBA:ARBA00023154};
KW NADP {ECO:0000256|ARBA:ARBA00022857};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Polyamine biosynthesis {ECO:0000256|PROSITE-ProRule:PRU00354};
KW Reference proteome {ECO:0000313|Proteomes:UP000007431};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PROSITE-
KW ProRule:PRU00354}.
FT DOMAIN 11..246
FT /note="PABS"
FT /evidence="ECO:0000259|PROSITE:PS51006"
FT ACT_SITE 166
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00354"
SQ SEQUENCE 755 AA; 81586 MW; 611AF5980ECD418D CRC64;
MVLLSHPSIR DGWFRETSSQ WPGQAMSLKV NRILHVEKST YQDVLVFESA TYGNVLVLDG
VIQCTERDEF SYQEMITHLP LASHPCPKQV LVVGGGDGGV VREVLKYDCV EQVVLCDIDE
AVIRVSKQYL PHMSSLLASP KVTVHIGDGF SFLADNRATY DVIITDSSDP VGPAESLFQK
PYFELLHAAL APGGTTASQS ECLWLHLPLI KDVVSMARDI FPVVEYAYTT IPTYPSGQIG
FLVCSKDADG DLRSPARAVP GTAYYNADVH RAAFVLPEFA RSVLGGGPDV LPKFGREAKA
ALIAGQSKRT VLLLGSGFVA LPCAEYITRD PRNALTIGST TAVALDVSNT AALESAVAAH
DLVISLIPYT YHTAVIRAAT KSHTNVLTTS FVSPAIRALE PHILAAGITV MNEIGVDPGV
DHLYAVKFIN EAHAKGGKIR EFYSFCGGLP APEAANNPLG FKFSWSARGV LLALLNSARF
LEDGKLVEIS GPDVVGSARP YFITPALACV AYPNRDATQL QDAYGIPAAR TVKRGSLRFQ
GFCELARSLM RIGWLRTEEQ DWLVDGLTWA QISARSAGAK DANEASLVAK IKELSAFSSE
TEATQVLSGM QWIGLFSNET APVRSSNLLD TLCARLEEIM AFEPGERDLV LLQHKFVVEW
SNGEEVSQRP PSIPVPANLI GLQETFTSTL EQYGSPIGHS AMAFLVGTPC GIAAQLMLDG
VINKPGILAP YTPDICDPIR ALVEQEGIGM VERKL
//
