ID D8Q673_SCHCM Unreviewed; 348 AA.
AC D8Q673;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 24-JAN-2024, entry version 53.
DE RecName: Full=Enoyl reductase (ER) domain-containing protein {ECO:0000259|SMART:SM00829};
DE Flags: Fragment;
GN ORFNames=SCHCODRAFT_110065 {ECO:0000313|EMBL:EFI96588.1};
OS Schizophyllum commune (strain H4-8 / FGSC 9210) (Split gill fungus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Schizophyllaceae; Schizophyllum.
OX NCBI_TaxID=578458 {ECO:0000313|Proteomes:UP000007431};
RN [1] {ECO:0000313|EMBL:EFI96588.1, ECO:0000313|Proteomes:UP000007431}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H4-8 / FGSC 9210 {ECO:0000313|Proteomes:UP000007431};
RX PubMed=20622885; DOI=10.1038/nbt.1643;
RA Ohm R.A., de Jong J.F., Lugones L.G., Aerts A., Kothe E., Stajich J.E.,
RA de Vries R.P., Record E., Levasseur A., Baker S.E., Bartholomew K.A.,
RA Coutinho P.M., Erdmann S., Fowler T.J., Gathman A.C., Lombard V.,
RA Henrissat B., Knabe N., Kuees U., Lilly W.W., Lindquist E., Lucas S.,
RA Magnuson J.K., Piumi F., Raudaskoski M., Salamov A., Schmutz J.,
RA Schwarze F.W.M.R., vanKuyk P.A., Horton J.S., Grigoriev I.V.,
RA Woesten H.A.B.;
RT "Genome sequence of the model mushroom Schizophyllum commune.";
RL Nat. Biotechnol. 28:957-963(2010).
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC family. {ECO:0000256|ARBA:ARBA00008072}.
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DR EMBL; GL377307; EFI96588.1; -; Genomic_DNA.
DR RefSeq; XP_003031491.1; XM_003031445.1.
DR AlphaFoldDB; D8Q673; -.
DR STRING; 578458.D8Q673; -.
DR GeneID; 9592605; -.
DR KEGG; scm:SCHCO_02628054; -.
DR VEuPathDB; FungiDB:SCHCODRAFT_02628054; -.
DR eggNOG; KOG0023; Eukaryota.
DR HOGENOM; CLU_026673_11_2_1; -.
DR InParanoid; D8Q673; -.
DR OMA; VHGVWSC; -.
DR OrthoDB; 1638961at2759; -.
DR Proteomes; UP000007431; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR PANTHER; PTHR42940; ALCOHOL DEHYDROGENASE 1-RELATED; 1.
DR PANTHER; PTHR42940:SF8; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 11; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000007431}.
FT DOMAIN 15..341
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
FT NON_TER 348
FT /evidence="ECO:0000313|EMBL:EFI96588.1"
SQ SEQUENCE 348 AA; 36654 MW; 6DA14E626691F929 CRC64;
MGAPETMVAY LYKPGFDDLI RVDDYPVQKP GKGEVLCKVL VCGVCHSDVA ILNGYTADSR
TYVLGHEVCA TPIVLGENVD PSIKIGHRYA IQLINGCTHA LKPHQAAALQ GVGLGGPGGY
ADYITVPDNL LVPVPDNVPD KVAAIAADAG TTAYNAVVNT GQVKAGDRVL IIGVGGLGHL
AVQYAILQGA EVYVCDLKPE ARRLGLELGA VKAFSLVELS AAVSAPDPFT VHAVIDFAVS
AQTFTLGLSA LVGEGDHYPT DPRYVLVGVS GDNLVFTSGE ALFSAIQIRA NLYGPRSATE
AALELFANGS VKARVTAEPI ENVNKIIDEL RAYEVSGRKV LQINELEY
//
