ID D8TQA2_VOLCA Unreviewed; 1375 AA.
AC D8TQA2;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=Cyclic nucleotide-binding domain-containing protein {ECO:0000259|PROSITE:PS50042};
GN ORFNames=VOLCADRAFT_88910 {ECO:0000313|EMBL:EFJ50498.1};
OS Volvox carteri f. nagariensis.
OC Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Chlorophyceae;
OC CS clade; Chlamydomonadales; Volvocaceae; Volvox.
OX NCBI_TaxID=3068 {ECO:0000313|Proteomes:UP000001058};
RN [1] {ECO:0000313|EMBL:EFJ50498.1, ECO:0000313|Proteomes:UP000001058}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=f. Nagariensis / Eve {ECO:0000313|Proteomes:UP000001058};
RX PubMed=20616280; DOI=10.1126/science.1188800;
RA Prochnik S.E., Umen J., Nedelcu A.M., Hallmann A., Miller S.M., Nishii I.,
RA Ferris P., Kuo A., Mitros T., Fritz-Laylin L.K., Hellsten U., Chapman J.,
RA Simakov O., Rensing S.A., Terry A., Pangilinan J., Kapitonov V., Jurka J.,
RA Salamov A., Shapiro H., Schmutz J., Grimwood J., Lindquist E., Lucas S.,
RA Grigoriev I.V., Schmitt R., Kirk D., Rokhsar D.S.;
RT "Genomic analysis of organismal complexity in the multicellular green alga
RT Volvox carteri.";
RL Science 329:223-226(2010).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; GL378331; EFJ50498.1; -; Genomic_DNA.
DR RefSeq; XP_002948623.1; XM_002948577.1.
DR STRING; 3068.D8TQA2; -.
DR GeneID; 9624948; -.
DR KEGG; vcn:VOLCADRAFT_88910; -.
DR eggNOG; KOG0500; Eukaryota.
DR InParanoid; D8TQA2; -.
DR OrthoDB; 74296at2759; -.
DR Proteomes; UP000001058; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR CDD; cd00038; CAP_ED; 1.
DR Gene3D; 2.60.120.10; Jelly Rolls; 1.
DR InterPro; IPR000595; cNMP-bd_dom.
DR InterPro; IPR018490; cNMP-bd_dom_sf.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR PANTHER; PTHR45638; CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A; 1.
DR PANTHER; PTHR45638:SF11; CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A; 1.
DR Pfam; PF00027; cNMP_binding; 1.
DR SMART; SM00100; cNMP; 1.
DR SUPFAM; SSF51206; cAMP-binding domain-like; 1.
DR PROSITE; PS50042; CNMP_BINDING_3; 1.
PE 4: Predicted;
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Ligand-gated ion channel {ECO:0000256|ARBA:ARBA00023286};
KW Reference proteome {ECO:0000313|Proteomes:UP000001058};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 150..250
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
FT REGION 88..116
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 297..383
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 395..420
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 540..566
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 624..655
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 674..720
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 870..894
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 978..1010
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1231..1254
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1276..1295
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1315..1351
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 97..116
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 297..342
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 683..717
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 991..1010
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1375 AA; 142837 MW; BC92537972F85F6A CRC64;
MRGRKKVKPV SQRGIAECMT GPSIDKHAKG NVLNAEQTQK QQDKSEIFPD KVVWDGGAVV
GNASAMLLPA ATDDTGAITP AFHGGCDQHK RKLSPNQLDN NECGEAPNPS ARSAKRPQTQ
LSALAQLVLV MVPGPSHAQP FMHRHPQIQL FAFCERAFIW RLAQRLRLSV FMPKDIIYDV
GSVGHDMYII WRGVVVLTEP DGCMTALLTG GDHFGDLGVM TSNLPRPQRA VAMCATDAMI
LSRSDLQDAM RDFPASAELV KGRSQVQLED HEIGQAVWAA SMAAKYTIIQ QQHQQALANG
GEDGNEGDTE TSSAGQTAPI ITQRSIEAPQ LITTNRPGTP RNRQGLSVGA DDDYGGTLAI
ARSGDEPTLH TKAVTRTSDR EQQRQSLCIV KGTCEPPRAA TGAGGAGLRR RRDKAAAGSA
DAIRAHLATH GTSTGGGSGP VAEATTRTED QSVLTTASTL ESVLDSIQPA GACVLAARTC
SQSGSGRPSS LSHSSVDSLC EVLNLNKPTA GSTIDPMAHL TAERFVRGLA AAGHSTSHIS
RAGVSTAAAA RPRRQAPRLP VAMRPPGPSH VLNGVAYCHG GEPSGRQQPS VLPGRCFDNH
RHPRALWVPD DTCTLDRFLE WRSSTARGSS SNPPQRNGPP PVPEGDATAG YKAVPGATTP
WYHSAEVPFQ QYTTTRPTSP IASSSMPSPP PQPLPPTAPP HHQQPPASAP QPPPAPAALL
HNFDSNDFAA LERVRFSSQH PPEGGGVVRY LSKRARQEAT AVAAAATAAA AATAASNGGP
SVNVANPATA AAAATTSCST GTMAAAAAPP MLSTNEDDGS GCGGSCQHVQ AQAQAQAHAY
TYAHVHSHVH AYARVHPHSQ VQPQAHMTSQ DLDLNGDLGD ISGDSSPRQQ QRSPTGSQLL
LLAPQPFLGV DPLGELFGEQ PSQQVAANGG LSLSHRWHRG RLGGAPTAAA AAPSLAHWNF
PGDIATALDS VTEGSATRQL VGPVGRRSLP RTSTLHGSSH RASGSSNLAC RRASTGSGSA
GCDVDGWLND QLLQQQPSCR HARCAGCMAM EQQLAAAQER VESILADPLK EPSIKAVVQR
EVLAAVELLN SRTAELLQQL VEGLTETCAR TEDLFQDVSS VDERLQRLED EQGGVFGAAA
AVVMSASGGS SNGGSSLRRS PAVAAAAAAA AGGVGGVLVD TPVQGPETQG RSAVSPLAGL
IGPQSATSGQ MGVLLPLSTA AAAAAAPGIS TSSSIRPAIG SQSSLKQNHH QRRTSVLSMR
GLDELVVDAA PAGGNATSGL STAVAPSEPG LPAPATSITA ADTALLQATM NRAAGKNKRA
CGEPARTPAE VTPVPRTTDE SGDEASSCQR GICSFSEMQA SPAMSSSRRY LEDGR
//
