ID D8TYA5_VOLCA Unreviewed; 3604 AA.
AC D8TYA5;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 24-JAN-2024, entry version 51.
DE RecName: Full=PAS domain-containing protein {ECO:0000259|PROSITE:PS50112};
GN ORFNames=VOLCADRAFT_91916 {ECO:0000313|EMBL:EFJ47517.1};
OS Volvox carteri f. nagariensis.
OC Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Chlorophyceae;
OC CS clade; Chlamydomonadales; Volvocaceae; Volvox.
OX NCBI_TaxID=3068 {ECO:0000313|Proteomes:UP000001058};
RN [1] {ECO:0000313|EMBL:EFJ47517.1, ECO:0000313|Proteomes:UP000001058}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=f. Nagariensis / Eve {ECO:0000313|Proteomes:UP000001058};
RX PubMed=20616280; DOI=10.1126/science.1188800;
RA Prochnik S.E., Umen J., Nedelcu A.M., Hallmann A., Miller S.M., Nishii I.,
RA Ferris P., Kuo A., Mitros T., Fritz-Laylin L.K., Hellsten U., Chapman J.,
RA Simakov O., Rensing S.A., Terry A., Pangilinan J., Kapitonov V., Jurka J.,
RA Salamov A., Shapiro H., Schmutz J., Grimwood J., Lindquist E., Lucas S.,
RA Grigoriev I.V., Schmitt R., Kirk D., Rokhsar D.S.;
RT "Genomic analysis of organismal complexity in the multicellular green alga
RT Volvox carteri.";
RL Science 329:223-226(2010).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; GL378344; EFJ47517.1; -; Genomic_DNA.
DR RefSeq; XP_002951341.1; XM_002951295.1.
DR STRING; 3068.D8TYA5; -.
DR GeneID; 9617110; -.
DR KEGG; vcn:VOLCADRAFT_91916; -.
DR eggNOG; ENOG502S0RD; Eukaryota.
DR InParanoid; D8TYA5; -.
DR OrthoDB; 7014at2759; -.
DR Proteomes; UP000001058; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005230; F:extracellular ligand-gated monoatomic ion channel activity; IEA:InterPro.
DR GO; GO:0009881; F:photoreceptor activity; IEA:UniProtKB-KW.
DR GO; GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
DR CDD; cd00130; PAS; 2.
DR Gene3D; 2.70.170.10; Neurotransmitter-gated ion-channel ligand-binding domain; 2.
DR Gene3D; 1.20.58.390; Neurotransmitter-gated ion-channel transmembrane domain; 2.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR036734; Neur_chan_lig-bd_sf.
DR InterPro; IPR036719; Neuro-gated_channel_TM_sf.
DR InterPro; IPR038050; Neuro_actylchol_rec.
DR InterPro; IPR006029; Neurotrans-gated_channel_TM.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR NCBIfam; TIGR00229; sensory_box; 2.
DR PANTHER; PTHR31600; TINY MACROCYSTS PROTEIN B-RELATED; 1.
DR PANTHER; PTHR31600:SF2; TINY MACROCYSTS PROTEIN B-RELATED; 1.
DR Pfam; PF02932; Neur_chan_memb; 1.
DR Pfam; PF13426; PAS_9; 3.
DR SMART; SM00091; PAS; 3.
DR SUPFAM; SSF90112; Neurotransmitter-gated ion-channel transmembrane pore; 2.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50112; PAS; 2.
PE 4: Predicted;
KW Chromophore {ECO:0000256|ARBA:ARBA00022543};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Photoreceptor protein {ECO:0000256|ARBA:ARBA00022543};
KW Receptor {ECO:0000256|ARBA:ARBA00022543};
KW Reference proteome {ECO:0000313|Proteomes:UP000001058};
KW Sensory transduction {ECO:0000256|ARBA:ARBA00022606};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..3604
FT /note="PAS domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003124006"
FT TRANSMEM 282..303
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 315..334
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 340..361
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 656..674
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 694..720
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1026..1047
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1059..1078
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1084..1110
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1380..1399
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1426..1445
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1506..1526
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1561..1585
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1605..1626
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1655..1678
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1710..1735
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1755..1772
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1784..1805
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 2900..2921
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 3105..3126
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 3138..3156
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 3271..3294
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 3481..3502
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 2063..2116
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 2295..2333
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT REGION 442..465
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 479..503
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1199..1251
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2717..2858
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3163..3207
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3539..3604
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 447..465
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 483..500
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1222..1243
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2745..2761
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2843..2858
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3175..3207
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3539..3564
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3581..3595
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 3604 AA; 394316 MW; 7883B6D745571109 CRC64;
MPLFLLLLLL SSRLPETRAQ RPYPLMGADG PLPTNITNGT IPHSDISATV LLERVVKLLE
RENAYEVKPL VVKRAVWWLV LSWTDFNAGR VVQASTAATA GAAATSISTN CSRYCDSGGL
ASMGCCDGIW LPHIEMLNIL QYFEDQLPRY RINANPNTGI VTWSTRLVGK WYTPLDFRAY
PFEHQHLLFE FALADSQSTV AGLLWDHVAQ LNNTAHTKAP FSNASGSEQV AGYQAIAIHD
RYFANNTARG TTKPKHCGLF KKYDESRALY GPVVLVKRVS SYYVLTNLLP ILLITVITFV
VFFMPQKALG ERMGVVLTMF LSLTAMQFVF DFPAANYINA LQMVVLVSYG MIALACIESL
LVNRIATVSE HVSTKRTCVR KYGTLLASYS LAHLGPGLGS FTRSYGKGGS ANVGHRGGQV
VRASSLLSRL GSKGRSAAAS AATGAATGMG QAGSTNGSTA NSPRVEFPVV GSQGLLQETP
VRAPQSPSPP ITPPTKPIPK PAEASLVHDP TTAAAAAGPS LPTSYAVSTN GPWNGASDPT
AFSAPAPVTA SKHRTGSFGC CVYSGPPESD AGLLSADAAD PVTTPPQVLS PFASTRNYTS
FNVAQDEMCL PPITDQNANG DARCAGNDGC SGVSISLTNT RDNCVAMGHR YRKLGLWRTF
GLMLAALWGW AVSIAKAPRH LYQQCKEDPV FATFVATCID KWCCIISIIL YTVAISVLLV
IEVRVGDHKM MLGDAPGNML MPLQMPLFLL LLLLSSRLPE TRAQRPYPLM GADGPLPTNI
TNGTIPHSDI SATVLLERVV KLLERENAYE VKPLVVKRAV WWLVLSWTDF NAGRVVQAST
AATAGAAATS ISTNCSRYCD SGGLASMGCC DGIWLPHIEM LNILQYFEDQ LPRYRINANP
NTGIVTWSTR LVGKWYTPLD FRAYPFEHQH LLFEFALADS QSTVAGLLWD HVAQLNNTAH
TKAPFSNASG SEQVAGYQAI AIHDRYFANN TARGTTKPKH CGLFKKYDES RALYGPVVLV
KRVSSYYVLT NLLPIVLITV ITFVVFFMPQ KALGERMGVV LTMFLSLTAM QFVCDFPPAN
YINALQMVVI VSYIIIALAC IESLIVNRIA TVSECESMKK TFVQKYGALL ARRRHPGSRL
GSVARSYGKG GSANVGHRGG QMVRAPSLLS QLGSKGRSAA AAAATGAATG LGQAGYTNGS
TASSPRVEFP VVGSQGPLQE TPVPAPQSPS PPKTPPAKPI PKPAGASLPT SYAVSTNGPW
NGASDPTVFS APAPVTASKH RTGRFGCCVY SGPPESDAGL LSADAADPVT TTPQVLSPFA
STRKYTSFNA AQDEMCLPPI TDQNANGEAP CAGRVGIFLS HMSMRDSYVA KGHCHRKLGL
WRTFGLMLAA LWGWAVSIAK APRPLYQQCK EDSKFALFAA TRIDKWFSII SITLYTVAIS
VLLVIEVRVG DHKMMLGDAP GNMAGGGGGD VGANDLLEQN QTVQAAVFGV LYTLAKEKLD
RSKRFAVARL ALDFLQCFIL IVNPAYALKP CVPGWSIDTG AWYWKAVKWV HFSNPIVSKG
YHFFVSILYS LAAALAVSVV LCVWVGWCFK NDRFPYVWPI KMLRIVVATF FVVFYVGSLA
IFMVALSCRW FDPDHNKRFH LRAFPEVECL SMPHLVHGAV ALGCSVVFCF IAFAMTVADF
EMNPASRRWL SAPHARVEVR GLMVKTVMTV TVAVLSGLMR VQAVILSSSA AFLFWSYVRW
EPHFIEWINH VRAGLYAMVS WAGLMLLAIT FSPHRRDEHY QSKLTTIMVA GLLPALGAGF
LISFIRLRFS VKHAIRSFCH IDPNKSRLKD IYRFTDAREV EIVSRVCRKW TEDDVLDSDA
VKLSETIIKV GLSQFHDDVF LTITYSNFLI EVQNNYQSGV TQLQQAKKLE PSISDRFAIF
VREQEHKQKA QSQSSGESAV DLVSYVEFQR NYRLLLRAHK GALYATRHFW KQLLHHDVSF
NALARAFRQI EVSKTKADRT YKMVLDRYPS SVKLLRSYGR FLEEVKNDPW TAAKYYSEAD
KVEEQQENAA NDAMLSDAVG DGDPSSMLAQ VDEKNNAVAV INAVGIIQMA NKPLMKLFGY
KKGELEGKNI SILMPQPFSQ RHNGYLRNYT TTGKAKILDT VREVVAIHKD RFVFPLKIAV
TKVSGTGADS LFMGVLKPAE DDPTTVHAWM MTQGTILCVD QRFSDWFGRS PSEVVGRPFN
TLATEQDVLI KLLDLANAST EAEFQEGRVS SEQVHLLHKY TEPVACRLKI TLGGTDSQRI
FVVHVKRVRN DQTNMMVTDH KGRIMYMNTD LATALGYTPK QAVKMDISQL MSPPYSQLHY
KYMKEPPAKV PLQSCRNAAT VVMLDAKKQP HPVKPHLSIR EENDVITHVV NVEFSSWERG
LDERRLSLMV DEAGVIQSTS ETPMGVFGIK PASMVGHSIA EYVDTLSPLR SQLPDILKKM
MAMQAEKPGY TWRVGVHPPV DEVALASASA VAQAILAKNT RPALMGIEVK PPANEGDLPG
PPVLCGLRSP RPLIFASAAS ALACAYCHLF ELCFIDAAQR HGTTITVSLY KADMVTGVVL
VDHNMVVIKP NCCVLHTTGL CFGVSNQLML KRKISQFLDV PHNVHSEWLL SDHKVKGAMK
TGTTGRKIGP TRVISGFHED GQPLQLRMTA VAHENKRVNI KLNFASYWTG NTEIFMRTLS
GEGGRTQARP MEGFANLGQE PKTIGRSGRR VVVNTSGKGG VKWAGDAGAD DDEKSVKGGR
KEAALPHSPT NEKQDGGGGG GSDDGRKSDE GSMSDSGSGG SGGGDDAAEE GKDKLDALVD
PAANNGWGQS PANGWAQGVE DDQASGVSGS QVDGASVVSG SEAGGYQTDF KRGRRFKKLM
KLLSSAKAKA DLTRYNRHTY IVMAVLLLVH VVCFALFLVF LENQKKYVTE VHATQDTSTY
GLDVAILARA LDNVYKNQVN PNWYTWDDLQ TILDDMTYAI DRMEEGHQGL YLGFGKLRHL
GDVYELGAIW EGRTLNDTTY IDTRNPYFLS SKNSLWLMGN AFIAAGRELV SNHIRIANAT
NKNFLLNRDW QYINKNGPAS IASGYRLSLN GMVLRTWDSV GKVNMLGIGL LVAEGCVVCG
AAALYMWILL KQVARQRYGL YSVFLVIPTG FLRALASKHV QVDGEDDNDS DSDAGDDANA
NKERNAGNKD STGKGEGGDG KGEDEAKPVI LPGIKTKAVV VEMGEAAEAP QPLWRRTLRG
VSSLLGIDRK TLGNGGVDTG KRKLIRDNRD TMVLTVPFLI WGAVVIAIYT FSYLTLKKVA
EPLVNLDVAN RVKTKINRCV FTAQEVISQT DITSRTAWQA ELLIRQSDLE MFYDALLYGS
NNLPEMAFSH TKGTLFSGAA PAEMFFRNKD VCYVTKNPGR WCFPEGDMYH EVSANALDPM
IRRLIEEALL LGNDAHSDLN FNSTRFDYIW RVAFHQLMQG VWSANSIYTT AANANFGKVR
MAHIILFVLS LALVMLFLIF MFRPFIRRTA IEARQVAELL SQLPPEMDVE GLVASAMTNR
RRGEDEDEAV AGRQVRRSAD GRAVKGVAGR RASVEMRASE AAAAKKGRVA EDDDDASSVG
SSMG
//
