ID D8WW70_BORHE Unreviewed; 275 AA.
AC D8WW70;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=glycerophosphodiester phosphodiesterase {ECO:0000256|ARBA:ARBA00012247};
DE EC=3.1.4.46 {ECO:0000256|ARBA:ARBA00012247};
DE Flags: Fragment;
GN Name=glpQ {ECO:0000313|EMBL:ADJ67694.1};
OS Borrelia hermsii.
OC Bacteria; Spirochaetota; Spirochaetia; Spirochaetales; Borreliaceae;
OC Borrelia.
OX NCBI_TaxID=140 {ECO:0000313|EMBL:ADJ67694.1};
RN [1] {ECO:0000313|EMBL:ADJ67694.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=HS1 {ECO:0000313|EMBL:ADJ67694.1};
RX PubMed=20463158; DOI=10.1128/JCM.00541-10;
RA Toledo A., Anda P., Escudero R., Larsson C., Bergstrom S., Benach J.L.;
RT "Phylogenetic analysis of a virulent Borrelia species isolated from
RT patients with relapsing fever.";
RL J. Clin. Microbiol. 48:2484-2489(2010).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a sn-glycero-3-phosphodiester + H2O = an alcohol + H(+) + sn-
CC glycerol 3-phosphate; Xref=Rhea:RHEA:12969, ChEBI:CHEBI:15377,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:30879, ChEBI:CHEBI:57597,
CC ChEBI:CHEBI:83408; EC=3.1.4.46;
CC Evidence={ECO:0000256|ARBA:ARBA00029315};
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DR EMBL; GU357580; ADJ67694.1; -; Genomic_DNA.
DR AlphaFoldDB; D8WW70; -.
DR GO; GO:0008081; F:phosphoric diester hydrolase activity; IEA:InterPro.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR CDD; cd08600; GDPD_EcGlpQ_like; 1.
DR Gene3D; 3.20.20.190; Phosphatidylinositol (PI) phosphodiesterase; 1.
DR InterPro; IPR030395; GP_PDE_dom.
DR InterPro; IPR017946; PLC-like_Pdiesterase_TIM-brl.
DR PANTHER; PTHR43620:SF7; GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE GDPD6; 1.
DR PANTHER; PTHR43620; GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE; 1.
DR Pfam; PF03009; GDPD; 1.
DR SUPFAM; SSF51695; PLC-like phosphodiesterases; 1.
DR PROSITE; PS51704; GP_PDE; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 1..275
FT /note="GP-PDE"
FT /evidence="ECO:0000259|PROSITE:PS51704"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ADJ67694.1"
FT NON_TER 275
FT /evidence="ECO:0000313|EMBL:ADJ67694.1"
SQ SEQUENCE 275 AA; 31785 MW; 00BA8BCC23AC62B0 CRC64;
ASGYLPEHTL EAKAYAYALG ADYLEQDIVL TKDNIPVIMH DPELDTTTNV AKLFPERARE
NGRYYSVDFT LDELKSLSLS ERFDPASRNP IYPNRFPLNE HDFKIPTLEE EIQFIQGLNK
STGRNVGIYP EIKKPLWHKQ QGKDISKIVI EILNKYGYKS KEDKIYLQTF DFDELKRIRE
ELGYQGKLIM LVGENDWDEA PTDYEYIKSE EGMAEVAKYS DGIGPWIPQI IIEGKITDLT
SLAHKHNMEV HPYTFRIDAL PSYVKDADEL LDLLF
//
