ID   D9HN58_PLAFA            Unreviewed;       644 AA.
AC   D9HN58;
DT   05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2010, sequence version 1.
DT   24-JAN-2024, entry version 27.
DE   SubName: Full=Duffy binding-like merozoite surface protein {ECO:0000313|EMBL:ADJ58671.1};
DE   Flags: Fragment;
GN   ORFNames=PF10_0348 {ECO:0000313|EMBL:ADJ58671.1};
OS   Plasmodium falciparum (malaria parasite P. falciparum).
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC   Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX   NCBI_TaxID=5833 {ECO:0000313|EMBL:ADJ58671.1};
RN   [1] {ECO:0000313|EMBL:ADJ58671.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=334 {ECO:0000313|EMBL:ADJ58671.1};
RX   PubMed=20457586; DOI=10.1093/molbev/msq119;
RA   Ochola L.I., Tetteh K.K., Stewart L.B., Riitho V., Marsh K., Conway D.J.;
RT   "Allele frequency-based and polymorphism-versus-divergence indices of
RT   balancing selection in a new filtered set of polymorphic genes in
RT   Plasmodium falciparum.";
RL   Mol. Biol. Evol. 0:0-0(2010).
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DR   EMBL; HM000297; ADJ58671.1; -; Genomic_DNA.
DR   AlphaFoldDB; D9HN58; -.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0046789; F:host cell surface receptor binding; IEA:InterPro.
DR   Gene3D; 1.20.58.830; -; 1.
DR   Gene3D; 1.20.1310.20; Duffy-antigen binding domain; 1.
DR   InterPro; IPR042202; Duffy-ag-bd_sf.
DR   InterPro; IPR008602; Duffy-antigen-binding.
DR   InterPro; IPR010784; Merozoite_SPAM.
DR   Pfam; PF05424; Duffy_binding; 1.
DR   Pfam; PF07133; Merozoite_SPAM; 1.
DR   SUPFAM; SSF140924; Duffy binding domain-like; 1.
PE   4: Predicted;
KW   Merozoite {ECO:0000313|EMBL:ADJ58671.1}.
FT   DOMAIN          153..298
FT                   /note="Duffy-antigen binding"
FT                   /evidence="ECO:0000259|Pfam:PF05424"
FT   REGION          441..466
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          480..501
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          537..614
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        480..495
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        538..592
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        593..614
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:ADJ58671.1"
FT   NON_TER         644
FT                   /evidence="ECO:0000313|EMBL:ADJ58671.1"
SQ   SEQUENCE   644 AA;  73735 MW;  5C81B5F034920066 CRC64;
     DSNLRNGLLN NSLDLTNGLN NKDNSFIDSK IEEHENKSYQ NKDNNISIVG QDVPITSVDS
     SKIINANDLE GNSIDDTKGL SVTNSGFDDG SAFGGGLPFS GYSPLQGNHN KCPDENFCKG
     IKNVLSCPPK NSTGRNGDWI SVAVKESSTT NKGVLVPPRR TKLCLRNINK VWHRIKDEKN
     FKEEFVKVAL GESNALMKHY KEKNLNALTA IKYGFSDMGD IIKGTDLIDY QITKNINRAL
     DKILRNETSN DKIKKRVDWW EANKSAFWDA FMCGYKVHIG NKPCPEHDNM DRIPQYLRWF
     REWGTYVCSE YKNKFENVIE LCNVRQITNQ NDSQLLEISK EDKCKGALKH YEEWVNRRRP
     EWKGQCDKFE KEKSKYEDTK SRTAEIYLKE ICSECDCKYK DLDNTFKEFK DNVTLLKAVI
     DNKKNQDSLT TTSLSTSINS VRDSSNLDQR GNITTSQGNS HRATVVQQAD QTNRLDNVNS
     VTQRGNNNYN NNLERGLGSG ALPGTNIITE EKYSLELIKL TSKDEEDIIK HNEDVREEIE
     EQQEDIEEDE EELENEGEET KEEDDEEKNE TNDTEDTDDT EDTEDIEEEN EEKELSNQQQ
     SEKKSISKVD EDSYRILSVS YKDNNEVKNV AESIVKKLFS LFND
//