ID D9HNA2_PLAFA Unreviewed; 723 AA.
AC D9HNA2;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE SubName: Full=Putative erythrocyte membrane protein {ECO:0000313|EMBL:ADI99324.1};
DE Flags: Fragment;
GN ORFNames=PF10_0355 {ECO:0000313|EMBL:ADI99324.1};
OS Plasmodium falciparum (malaria parasite P. falciparum).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX NCBI_TaxID=5833 {ECO:0000313|EMBL:ADI99324.1};
RN [1] {ECO:0000313|EMBL:ADI99324.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=128 {ECO:0000313|EMBL:ADI99324.1}, and 216
RC {ECO:0000313|EMBL:ADI99336.1};
RX PubMed=20457586; DOI=10.1093/molbev/msq119;
RA Ochola L.I., Tetteh K.K., Stewart L.B., Riitho V., Marsh K., Conway D.J.;
RT "Allele frequency-based and polymorphism-versus-divergence indices of
RT balancing selection in a new filtered set of polymorphic genes in
RT Plasmodium falciparum.";
RL Mol. Biol. Evol. 0:0-0(2010).
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DR EMBL; HM000344; ADI99324.1; -; Genomic_DNA.
DR EMBL; HM000356; ADI99336.1; -; Genomic_DNA.
DR AlphaFoldDB; D9HNA2; -.
DR VEuPathDB; PlasmoDB:Pf7G8-2_000321400; -.
DR VEuPathDB; PlasmoDB:Pf7G8_100040400; -.
DR VEuPathDB; PlasmoDB:PfCD01_100041200; -.
DR VEuPathDB; PlasmoDB:PfGA01_100041300; -.
DR VEuPathDB; PlasmoDB:PfGN01_100041500; -.
DR VEuPathDB; PlasmoDB:PfKH01_100040500; -.
DR VEuPathDB; PlasmoDB:PfKH02_100041400; -.
DR VEuPathDB; PlasmoDB:PfSD01_100040600; -.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0046789; F:host cell surface receptor binding; IEA:InterPro.
DR Gene3D; 1.20.58.830; -; 1.
DR Gene3D; 1.20.1310.20; Duffy-antigen binding domain; 1.
DR InterPro; IPR042202; Duffy-ag-bd_sf.
DR InterPro; IPR008602; Duffy-antigen-binding.
DR InterPro; IPR010784; Merozoite_SPAM.
DR Pfam; PF05424; Duffy_binding; 1.
DR Pfam; PF07133; Merozoite_SPAM; 1.
DR SUPFAM; SSF140924; Duffy binding domain-like; 1.
PE 4: Predicted;
FT DOMAIN 178..324
FT /note="Duffy-antigen binding"
FT /evidence="ECO:0000259|Pfam:PF05424"
FT REGION 445..566
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 604..687
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 454..504
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 512..533
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 604..645
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 646..687
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ADI99324.1"
FT NON_TER 723
FT /evidence="ECO:0000313|EMBL:ADI99324.1"
SQ SEQUENCE 723 AA; 82691 MW; C4C4A507D04B5C0B CRC64;
STCFVVNEGN PNLRNNIIND DDLKGKAYNN TIDANNQNIE YNKNLEHNVN SSHISKFSDI
MDQEDKGDNE NSHDIKFEEK KNINKSLDAE SNYGINEISI TGNDSNSDNS NQNIFPDGSE
LAGGIPRSIY TINLGFNKCP TEEICKDFSN LPQCRKNVHE RNNWLGSSVK NFSSDNKGVL
VPPRRQSLCL RITLQDFRTK KKKEGDFEKF IYSYASSEAK KLRTIHNNIS EKALQAIKYS
FADIGNIIKG DDLLDTPTSN NTKTYLEEVL KLHNKNNETK DAKKWWTENR YHVWEAMMCG
YQNEKKDNEC TVYGNIDDIP QFLRWFREWG TYVCEESENN MKTLKAVCFP KQLRTETNSA
MTVTQKGTCS STLKNYEEWY NKRKNEWTEQ SIKYNKDKTK YKDIENLSPS NYLIKKCPEC
KCTEKNLHDV FEHTFDGKAL LKKLEEEESP ASDSVRTSTE SGPITVPDSS LNQTTQQENQ
PGVEKPLTTV VMNEHQGQTD PNTDDNSGET EHNKSNVGSI QEVNQGSVSE ESHSKTIDPS
KIDDRLELSS GSSSLEQHSK EDVKKGSTLE LVPLSLSDIE QIANESEDVL EEIEEEINTD
GEIEYITEEE IKEDIEEETE EDIEEETEEE TEEETEEEAD EETVKEIEDK PEQEIKNKSL
EEKQIDKNTD TSEKKGFNNS EKDEKARNLI SKNYKNYNEL DKNVHTLVNS IISLLEEGNG
SDS
//
