ID D9ISA4_HBV Unreviewed; 124 AA.
AC D9ISA4;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 14-DEC-2022, entry version 22.
DE SubName: Full=Polymerase {ECO:0000313|EMBL:ADJ97350.1};
DE Flags: Fragment;
GN Name=P {ECO:0000313|EMBL:ADJ97350.1};
OS Hepatitis B virus (HBV).
OC Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes;
OC Blubervirales; Hepadnaviridae; Orthohepadnavirus.
OX NCBI_TaxID=10407 {ECO:0000313|EMBL:ADJ97350.1};
OH NCBI_TaxID=9606; Homo sapiens (Human).
OH NCBI_TaxID=9598; Pan troglodytes (Chimpanzee).
RN [1] {ECO:0000313|EMBL:ADJ97350.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=196_011007 {ECO:0000313|EMBL:ADJ97350.1};
RX PubMed=20875460; DOI=10.1016/j.antiviral.2010.09.012;
RA Rhee S.Y., Margeridon-Thermet S., Nguyen M.H., Liu T.F., Kagan R.M.,
RA Beggel B., Verheyen J., Kaiser R., Shafer R.W.;
RT "Hepatitis B virus reverse transcriptase sequence variant database for
RT sequence analysis and mutation discovery.";
RL Antiviral Res. 88:269-275(2010).
RN [2] {ECO:0000313|EMBL:ADJ97350.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=196_011007 {ECO:0000313|EMBL:ADJ97350.1};
RA Rhee S.-Y., Margeridon-Thermet S., Liu T.F., Nguyen M.H., Kagan R.M.,
RA Beggel B., Verheyen J., Kaiser R., Shafer R.W.;
RL Submitted (APR-2010) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; HM174217; ADJ97350.1; -; Genomic_DNA.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.30.70.270; -; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR000477; RT_dom.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR PROSITE; PS50878; RT_POL; 1.
PE 4: Predicted;
KW DNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00022932};
KW Endonuclease {ECO:0000256|ARBA:ARBA00022759};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW RNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00022918};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 1..124
FT /note="Reverse transcriptase"
FT /evidence="ECO:0000259|PROSITE:PS50878"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ADJ97350.1"
FT NON_TER 124
FT /evidence="ECO:0000313|EMBL:ADJ97350.1"
SQ SEQUENCE 124 AA; 14052 MW; B1CB1004FF784AEE CRC64;
GLSRYVARLS SNSRINNNQY GTMQNLHDSC SRQLYVSLML LYKTYGWKLH LYSHPIVLGF
RKIPMGVGLS PFLLAQFTSA ICSVVRRAFP HCLAFSYMDD VVLGAKSVQH RESLYTAVTN
FLLS
//
