ID D9MWX5_9ALTE Unreviewed; 355 AA.
AC D9MWX5;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=DNA gyrase subunit B {ECO:0000256|ARBA:ARBA00019166};
DE EC=5.6.2.2 {ECO:0000256|ARBA:ARBA00012895};
DE Flags: Fragment;
GN Name=gyrB {ECO:0000313|EMBL:ADK23799.1};
OS Alteromonas sp. P127.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC Alteromonadaceae; Alteromonas/Salinimonas group; Alteromonas.
OX NCBI_TaxID=860771 {ECO:0000313|EMBL:ADK23799.1};
RN [1] {ECO:0000313|EMBL:ADK23799.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=P127 {ECO:0000313|EMBL:ADK23799.1};
RA Zhong H., Lai Q., Shao Z.;
RT "Isolation and characterization of Alteromonas sp. P127, a polycyclic
RT aromatic hydrocarbon-degrading deep-sea bacterium.";
RL Submitted (JUN-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP-dependent breakage, passage and rejoining of double-
CC stranded DNA.; EC=5.6.2.2; Evidence={ECO:0000256|ARBA:ARBA00000185};
CC -!- SIMILARITY: Belongs to the type II topoisomerase GyrB family.
CC {ECO:0000256|ARBA:ARBA00010708}.
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DR EMBL; HM490143; ADK23799.1; -; Genomic_DNA.
DR AlphaFoldDB; D9MWX5; -.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003918; F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity; IEA:UniProtKB-EC.
DR GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR CDD; cd00822; TopoII_Trans_DNA_gyrase; 1.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.40.50.670; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR InterPro; IPR001241; Topo_IIA.
DR InterPro; IPR013760; Topo_IIA-like_dom_sf.
DR InterPro; IPR000565; Topo_IIA_B.
DR InterPro; IPR013759; Topo_IIA_B_C.
DR InterPro; IPR013506; Topo_IIA_bsu_dom2.
DR InterPro; IPR018522; TopoIIA_CS.
DR InterPro; IPR006171; TOPRIM_domain.
DR PANTHER; PTHR45866:SF1; DNA GYRASE SUBUNIT B, MITOCHONDRIAL; 1.
DR PANTHER; PTHR45866; DNA GYRASE/TOPOISOMERASE SUBUNIT B; 1.
DR Pfam; PF00204; DNA_gyraseB; 1.
DR Pfam; PF01751; Toprim; 1.
DR PRINTS; PR01159; DNAGYRASEB.
DR PRINTS; PR00418; TPI2FAMILY.
DR SMART; SM00433; TOP2c; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR SUPFAM; SSF56719; Type II DNA topoisomerase; 1.
DR PROSITE; PS00177; TOPOISOMERASE_II; 1.
DR PROSITE; PS50880; TOPRIM; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Topoisomerase {ECO:0000256|ARBA:ARBA00023029}.
FT DOMAIN 295..355
FT /note="Toprim"
FT /evidence="ECO:0000259|PROSITE:PS50880"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ADK23799.1"
FT NON_TER 355
FT /evidence="ECO:0000313|EMBL:ADK23799.1"
SQ SEQUENCE 355 AA; 39282 MW; 877FE18CAE732BF0 CRC64;
NALSSRLKLR IRRGGKAHEQ EYHHGVPQAP LAVTGDTDKT GTMIRFWPSS DTFTDTLYHY
DILAKRLREL SFLNSGVSIR LKDERDGKED HFMYEGGIKA FVEYLNEKKT PVHQKVFHFS
SEQEDGIAVE VAMQWNDSFQ ENVFCFTNNI PQRDGGTHLA GFRGALTRTL NNYMEKEGLN
KKAKTNASGD DAREGLTAVI SVKVPDPKFS SQTKDKLVSS EVRPAVESAM NEKLAEFLLE
NPAESKIIAG KIIDAARARE AARKAREMTR RKGALDLAGL PGKLADCQEK DPALSELYIV
EGDSAGGSAK QGRNRKNQAI LPLKGKILNV EKARFDKMLS SQEVATLITA LGCGI
//
