ID D9PTP7_CAEEL Unreviewed; 348 AA.
AC D9PTP7;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 24-JAN-2024, entry version 92.
DE SubName: Full=PX domain-containing protein {ECO:0000313|EMBL:CBW44402.1};
GN Name=snx-6 {ECO:0000313|EMBL:CBW44402.1,
GN ECO:0000313|WormBase:Y59A8B.22c};
GN ORFNames=CELE_Y59A8B.22 {ECO:0000313|EMBL:CBW44402.1}, Y59A8B.22
GN {ECO:0000313|WormBase:Y59A8B.22c};
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239 {ECO:0000313|EMBL:CBW44402.1, ECO:0000313|Proteomes:UP000001940};
RN [1] {ECO:0000313|EMBL:CBW44402.1, ECO:0000313|Proteomes:UP000001940}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2 {ECO:0000313|EMBL:CBW44402.1,
RC ECO:0000313|Proteomes:UP000001940};
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RA Sulson J.E., Waterston R.;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- SIMILARITY: Belongs to the sorting nexin family.
CC {ECO:0000256|ARBA:ARBA00010883}.
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DR EMBL; BX284605; CBW44402.1; -; Genomic_DNA.
DR RefSeq; NP_001256765.1; NM_001269836.1.
DR AlphaFoldDB; D9PTP7; -.
DR SMR; D9PTP7; -.
DR PeptideAtlas; D9PTP7; -.
DR EnsemblMetazoa; Y59A8B.22c.1; Y59A8B.22c.1; WBGene00013354.
DR GeneID; 190399; -.
DR AGR; WB:WBGene00013354; -.
DR WormBase; Y59A8B.22c; CE45286; WBGene00013354; snx-6.
DR HOGENOM; CLU_040966_0_0_1; -.
DR OrthoDB; 5398040at2759; -.
DR Proteomes; UP000001940; Chromosome V.
DR Bgee; WBGene00013354; Expressed in adult organism and 3 other cell types or tissues.
DR ExpressionAtlas; D9PTP7; baseline and differential.
DR GO; GO:0045335; C:phagocytic vesicle; IDA:WormBase.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR GO; GO:0043621; F:protein self-association; IPI:WormBase.
DR GO; GO:0090389; P:phagosome-lysosome fusion involved in apoptotic cell clearance; IMP:WormBase.
DR CDD; cd07621; BAR_SNX5_6; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR015404; Vps5_C.
DR PANTHER; PTHR45850:SF1; SORTING NEXIN 6, ISOFORM B; 1.
DR PANTHER; PTHR45850; SORTING NEXIN FAMILY MEMBER; 1.
DR Pfam; PF00787; PX; 1.
DR Pfam; PF09325; Vps5; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR PROSITE; PS50195; PX; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|EPD:D9PTP7,
KW ECO:0007829|PeptideAtlas:D9PTP7};
KW Reference proteome {ECO:0000313|Proteomes:UP000001940};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 1..114
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
SQ SEQUENCE 348 AA; 40345 MW; EC552781CD9CC54F CRC64;
MKPETAVVRE HEEFLWLHGT LEDNENYAGF IIPPAPPKPN FDSSREKLQK LGEGEATMTK
EEFLKMKHDL EQDYLAQFKK TVAMHEVFLQ RIAAHPVFKN DQNFRIFLQY ENELSVRGKN
KKEQVESFWK RFTQSADEVL LSGQKDVDEF FEKEKNYMVE YNIHIKEAAA KSEKLIAARK
NVVASFSKIG DSFERIARGE PNKSLARTFA QGADAMFKLK KVESRSSNDE ELKLGDTLHY
FARDTQAAKD LLYRRMRCLA NYEAANKNLE RARAKNREIP KAEAEQSEAC KKFEEITGLS
KNELKELKTR RVQAFKKNLT DLAELEIKHS KAEISLLRDV VERLKSSQ
//
