ID D9PZN1_ACIS3 Unreviewed; 387 AA.
AC D9PZN1;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Predicted Fe-S oxidoreductase {ECO:0000313|EMBL:ADL18519.1};
GN OrderedLocusNames=ASAC_0111 {ECO:0000313|EMBL:ADL18519.1};
OS Acidilobus saccharovorans (strain DSM 16705 / JCM 18335 / VKM B-2471 /
OS 345-15).
OC Archaea; Thermoproteota; Thermoprotei; Acidilobales; Acidilobaceae;
OC Acidilobus.
OX NCBI_TaxID=666510 {ECO:0000313|EMBL:ADL18519.1, ECO:0000313|Proteomes:UP000000346};
RN [1] {ECO:0000313|EMBL:ADL18519.1, ECO:0000313|Proteomes:UP000000346}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 16705 / JCM 18335 / VKM B-2471 / 345-15
RC {ECO:0000313|Proteomes:UP000000346};
RX PubMed=20581186; DOI=10.1128/AEM.00599-10;
RA Mardanov A.V., Svetlitchnyi V.A., Beletsky A.V., Prokofeva M.I.,
RA Bonch-Osmolovskaya E.A., Ravin N.V., Skryabin K.G.;
RT "The genome sequence of the crenarchaeon Acidilobus saccharovorans supports
RT a new order, Acidilobales, and suggests an important ecological role in
RT terrestrial acidic hot springs.";
RL Appl. Environ. Microbiol. 76:5652-5657(2010).
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
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DR EMBL; CP001742; ADL18519.1; -; Genomic_DNA.
DR RefSeq; WP_013266031.1; NC_014374.1.
DR AlphaFoldDB; D9PZN1; -.
DR STRING; 666510.ASAC_0111; -.
DR GeneID; 9498324; -.
DR KEGG; asc:ASAC_0111; -.
DR eggNOG; arCOG00940; Archaea.
DR HOGENOM; CLU_009273_4_0_2; -.
DR InParanoid; D9PZN1; -.
DR OrthoDB; 30736at2157; -.
DR Proteomes; UP000000346; Chromosome.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd01335; Radical_SAM; 1.
DR CDD; cd21123; SPASM_MftC-like; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR023885; 4Fe4S-binding_SPASM_dom.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR006638; Elp3/MiaA/NifB-like_rSAM.
DR InterPro; IPR017200; PqqE-like.
DR InterPro; IPR007197; rSAM.
DR NCBIfam; TIGR04053; TIGR04053 family radical SAM/SPASM domain-containing protein; 1.
DR PANTHER; PTHR11228; RADICAL SAM DOMAIN PROTEIN; 1.
DR PANTHER; PTHR11228:SF34; TUNGSTEN-CONTAINING ALDEHYDE FERREDOXIN OXIDOREDUCTASE COFACTOR MODIFYING PROTEIN; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR Pfam; PF13186; SPASM; 1.
DR PIRSF; PIRSF037420; PQQ_syn_pqqE; 1.
DR SFLD; SFLDG01386; main_SPASM_domain-containing; 1.
DR SFLD; SFLDG01067; SPASM/twitch_domain_containing; 1.
DR SMART; SM00729; Elp3; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000000346};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
FT DOMAIN 10..234
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 387 AA; 42907 MW; 76612F9373658C46 CRC64;
MSRRGRWPFE EKPLLVFWET TKACPLACIH CRAEAITRPL PGELSHAEGL ELVRQVAEFG
RPYPILVFTG GDPLSREDIW ELVDEAHSLG VPVAMAPSPS RALLDNLDRI ASGKVSAVSI
SIDHPSPEVH DKVRRYQGSW EAGVTAIREL IRRGVKVQVN TAVMRSTVDG LPGMVKLLKD
LGVDVWEVFY LVPVGRAEAR EDLTPQEWED VSAFLYEASR YGINVRTSEG PMFRRVSLLL
NYARSRNLEP SKLVKLGDLY LRLTGQLRAL LGEPGEEARF ETSGTRDGKG IAFISHDGMV
YPSGFLPVPV GNVRRERLVD IYRRSRLMVS LREASFRGRC GSCEFKEICG GSRARAFAYS
GDPLGEDPAC PYVPGSLGVN VKEVMAP
//
