ID D9QNK3_BRESC Unreviewed; 490 AA.
AC D9QNK3;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=Pyridine nucleotide-disulfide oxidoreductase {ECO:0000313|EMBL:ADL02238.1};
GN OrderedLocusNames=Bresu_2932 {ECO:0000313|EMBL:ADL02238.1};
OS Brevundimonas subvibrioides (strain ATCC 15264 / DSM 4735 / LMG 14903 /
OS NBRC 16000 / CB 81) (Caulobacter subvibrioides).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Caulobacterales;
OC Caulobacteraceae; Brevundimonas.
OX NCBI_TaxID=633149 {ECO:0000313|EMBL:ADL02238.1, ECO:0000313|Proteomes:UP000002696};
RN [1] {ECO:0000313|Proteomes:UP000002696}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 15264 / DSM 4735 / LMG 14903 / NBRC 16000 / CB 81
RC {ECO:0000313|Proteomes:UP000002696};
RX PubMed=21705585; DOI=10.1128/JB.05453-11;
RG US DOE Joint Genome Institute;
RA Brown P.J., Kysela D.T., Buechlein A., Hemmerich C., Brun Y.V.;
RT "Genome sequences of eight morphologically diverse alphaproteobacteria.";
RL J. Bacteriol. 193:4567-4568(2011).
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DR EMBL; CP002102; ADL02238.1; -; Genomic_DNA.
DR RefSeq; WP_013270339.1; NC_014375.1.
DR AlphaFoldDB; D9QNK3; -.
DR STRING; 633149.Bresu_2932; -.
DR KEGG; bsb:Bresu_2932; -.
DR eggNOG; COG0665; Bacteria.
DR HOGENOM; CLU_022247_1_0_5; -.
DR InParanoid; D9QNK3; -.
DR OrthoDB; 5695497at2; -.
DR BioCyc; BSUB633149:G1GM8-2951-MONOMER; -.
DR Proteomes; UP000002696; Chromosome.
DR GO; GO:0004497; F:monooxygenase activity; IEA:InterPro.
DR GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR006905; Flavin_halogenase.
DR InterPro; IPR033856; Trp_halogen.
DR PANTHER; PTHR43747; FAD-BINDING PROTEIN; 1.
DR PANTHER; PTHR43747:SF4; FLAVIN-DEPENDENT TRYPTOPHAN HALOGENASE; 1.
DR Pfam; PF04820; Trp_halogenase; 1.
DR PIRSF; PIRSF011396; Trp_halogenase; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 4: Predicted;
KW FAD {ECO:0000256|PIRSR:PIRSR011396-2};
KW Flavoprotein {ECO:0000256|PIRSR:PIRSR011396-2};
KW Nucleotide-binding {ECO:0000256|PIRSR:PIRSR011396-2};
KW Reference proteome {ECO:0000313|Proteomes:UP000002696}.
FT ACT_SITE 83
FT /evidence="ECO:0000256|PIRSR:PIRSR011396-1"
FT BINDING 17..20
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR011396-2"
FT BINDING 83
FT /ligand="7-chloro-L-tryptophan"
FT /ligand_id="ChEBI:CHEBI:58713"
FT /evidence="ECO:0000256|PIRSR:PIRSR011396-2"
FT BINDING 190
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR011396-2"
FT BINDING 337
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR011396-2"
FT BINDING 346
FT /ligand="L-tryptophan"
FT /ligand_id="ChEBI:CHEBI:57912"
FT /evidence="ECO:0000256|PIRSR:PIRSR011396-2"
FT BINDING 350
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR011396-2"
SQ SEQUENCE 490 AA; 54076 MW; BC7145715A98566A CRC64;
MQETDPGAIR SIAIVGGGTA GWMSAVLLGH ALRGSDVRIT VVESAEIGIV GVGEATIPPI
LDFLDLVGID REAFIRETEA TLKLGIRFQD WKTVGEHYWH PFGTFGVAID RRPFHHHLQR
AAAWDEPRGV VDFSLAAALA EAGRFTPPDP REGPARAGLR YALHFDAALV ARTLRTVAER
RGVRRLDRTV VDVTRTPAGH VDELLFREGD RLGADLFIDC SGFRGLLIEG AMAAGYEDWT
RWLPCDRAVA GPTALNGEPQ LYTLSHARDA GWRWRIPLQH RAGNGYVYSS RHIDDQAALD
DLTRQVGGTF LAEPRQLRFT TGRRKAFWKG NVVALGLASG FLEPLESTSI HLVTSGLYKL
LDHFPDRTFD PANIAAYNAS LIEEYETIRD FIVAHYGLSA RRDTPFWRDV TGQSLPDSLQ
SRIDLYRATG RCRARPGDLF ADVNWFYVLH GLGLRPRHPD PLTGMSDAAA VRGVFDQVAR
DVAAGVSAAR
//
