ID D9TDB9_MICAI Unreviewed; 555 AA.
AC D9TDB9;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=Copper resistance protein CopC {ECO:0000313|EMBL:ADL44757.1};
GN OrderedLocusNames=Micau_1195 {ECO:0000313|EMBL:ADL44757.1};
OS Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / BCRC 12538 / CBS
OS 129.76 / JCM 10878 / NBRC 16125 / NRRL B-16091 / INA 9442).
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Micromonospora.
OX NCBI_TaxID=644283 {ECO:0000313|EMBL:ADL44757.1, ECO:0000313|Proteomes:UP000001908};
RN [1] {ECO:0000313|EMBL:ADL44757.1, ECO:0000313|Proteomes:UP000001908}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442
RC {ECO:0000313|Proteomes:UP000001908};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA Pitluck S., Chertkov O., Detter J.C., Han C., Tapia R., Land M., Hauser L.,
RA Chang Y.-J., Jeffries C., Kyrpides N., Ivanova N., Ovchinnikova G.,
RA Hirsch A.M., Woyke T.;
RT "Complete sequence of Micromonospora aurantiaca ATCC 27029.";
RL Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP002162; ADL44757.1; -; Genomic_DNA.
DR RefSeq; WP_013284396.1; NC_014391.1.
DR AlphaFoldDB; D9TDB9; -.
DR STRING; 644283.Micau_1195; -.
DR KEGG; mau:Micau_1195; -.
DR eggNOG; COG1276; Bacteria.
DR eggNOG; COG2372; Bacteria.
DR HOGENOM; CLU_023176_0_0_11; -.
DR OrthoDB; 5242236at2; -.
DR Proteomes; UP000001908; Chromosome.
DR GO; GO:0042597; C:periplasmic space; IEA:InterPro.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0005507; F:copper ion binding; IEA:InterPro.
DR GO; GO:0006825; P:copper ion transport; IEA:InterPro.
DR GO; GO:0046688; P:response to copper ion; IEA:InterPro.
DR Gene3D; 2.60.40.1220; -; 1.
DR InterPro; IPR032694; CopC/D.
DR InterPro; IPR007348; CopC_dom.
DR InterPro; IPR008457; Cu-R_CopD_dom.
DR InterPro; IPR014755; Cu-Rt/internalin_Ig-like.
DR InterPro; IPR014756; Ig_E-set.
DR PANTHER; PTHR34820; INNER MEMBRANE PROTEIN YEBZ; 1.
DR PANTHER; PTHR34820:SF4; INNER MEMBRANE PROTEIN YEBZ; 1.
DR Pfam; PF04234; CopC; 1.
DR Pfam; PF05425; CopD; 1.
DR SUPFAM; SSF81296; E set domains; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Copper {ECO:0000256|ARBA:ARBA00023008};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001908};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 162..182
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 194..214
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 234..257
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 269..291
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 303..324
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 336..360
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 372..393
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 414..432
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 40..133
FT /note="CopC"
FT /evidence="ECO:0000259|Pfam:PF04234"
FT DOMAIN 334..431
FT /note="Copper resistance protein D"
FT /evidence="ECO:0000259|Pfam:PF05425"
FT REGION 131..150
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 136..150
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 555 AA; 57358 MW; A1B68D03FF5E0638 CRC64;
MTAAVRRPSR VVAARSGAVA GLLLLLVALL LTPATPAAAH AVLVSSSPAA SAVVPEAPAQ
VVITFSEGVR KVPGKVRVIA PDGSRADRGE PTFQGAEVTI PVDPSGGRGT YLVSYRVISA
DSHPVSGAFT YSVGAPSEPP SDSGSDNRAN PVTENAVKVA KYAGYTGLLL LVGPALVLAA
LWPRRLSRRG PARLAWTGLG LLAVATVAEV WLQVPYVNGG GLFDVTGSGL GDVLGSAYGT
THLVRLGLLA AAAFLLRPLF AGPIGRTDGI ILAVLGGAAL FTWPLAGHAA ASPAPAVSVV
VDAVHLGGMA VWLGGLVMLA VFLLRRADER ELDAILPIWS RWAALAVAAL LLAGTVQGLI
EVASIQALFD TTYGRLLLAK IVLFALVIGV AAYSRALVRR RVAAGRPGAM RRAVVAELVI
TAVVLGVSAT LVQTTPARTA AANVAGAEQG YFSTTLSSPI YSLEVQLDPA ETGNNSMHLY
AYTKDSRPQP VQEWKVTAAL PSAGIEPITV PLLPLSDNHA TGEVNLPARG DWQLRITVRT
TDIDQATVTA TVPIK
//
