ID D9VSV3_9ACTN Unreviewed; 671 AA.
AC D9VSV3;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=Fumarate reductase, flavoprotein subunit {ECO:0000313|EMBL:EFL18904.1};
GN ORFNames=SSNG_06156 {ECO:0000313|EMBL:EFL18904.1};
OS Streptomyces sp. C.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=253839 {ECO:0000313|EMBL:EFL18904.1, ECO:0000313|Proteomes:UP000005763};
RN [1] {ECO:0000313|EMBL:EFL18904.1, ECO:0000313|Proteomes:UP000005763}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C {ECO:0000313|EMBL:EFL18904.1,
RC ECO:0000313|Proteomes:UP000005763};
RG The Broad Institute Genome Sequencing Platform;
RG Broad Institute Microbial Sequencing Center;
RA Fischbach M., Godfrey P., Ward D., Young S., Zeng Q., Koehrsen M.,
RA Alvarado L., Berlin A.M., Bochicchio J., Borenstein D., Chapman S.B.,
RA Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A.,
RA Gujja S., Heilman E.R., Heiman D.I., Hepburn T.A., Howarth C., Jen D.,
RA Larson L., Lewis B., Mehta T., Park D., Pearson M., Richards J.,
RA Roberts A., Saif S., Shea T.D., Shenoy N., Sisk P., Stolte C., Sykes S.N.,
RA Thomson T., Walk T., White J., Yandava C., Straight P., Clardy J., Hung D.,
RA Kolter R., Mekalanos J., Walker S., Walsh C.T., Wieland-Brown L.C.,
RA Haas B., Nusbaum C., Birren B.;
RT "Annotation of Streptomyces sp. strain C.";
RL Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; GG657750; EFL18904.1; -; Genomic_DNA.
DR RefSeq; WP_007267829.1; NZ_GG657750.1.
DR AlphaFoldDB; D9VSV3; -.
DR STRING; 253839.SSNG_06156; -.
DR eggNOG; COG1053; Bacteria.
DR HOGENOM; CLU_014312_7_0_11; -.
DR Proteomes; UP000005763; Unassembled WGS sequence.
DR GO; GO:0033765; F:steroid dehydrogenase activity, acting on the CH-CH group of donors; IEA:UniProt.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR Gene3D; 1.20.58.100; Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain; 1.
DR Gene3D; 3.90.700.10; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
DR InterPro; IPR003953; FAD-binding_2.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR037099; Fum_R/Succ_DH_flav-like_C_sf.
DR InterPro; IPR015939; Fum_Rdtase/Succ_DH_flav-like_C.
DR InterPro; IPR030664; SdhA/FrdA/AprA.
DR InterPro; IPR011280; Succ_DH/Fum_Rdt_flav_su.
DR InterPro; IPR027477; Succ_DH/fumarate_Rdtase_cat_sf.
DR NCBIfam; TIGR01811; sdhA_Bsu; 1.
DR PANTHER; PTHR11632; SUCCINATE DEHYDROGENASE 2 FLAVOPROTEIN SUBUNIT; 1.
DR PANTHER; PTHR11632:SF53; SUCCINATE DEHYDROGENASE FLAVOPROTEIN SUBUNIT; 1.
DR Pfam; PF00890; FAD_binding_2; 1.
DR Pfam; PF02910; Succ_DH_flav_C; 1.
DR PRINTS; PR00368; FADPNR.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF46977; Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain; 1.
DR SUPFAM; SSF56425; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
PE 4: Predicted;
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 69..474
FT /note="FAD-dependent oxidoreductase 2 FAD binding"
FT /evidence="ECO:0000259|Pfam:PF00890"
FT DOMAIN 536..670
FT /note="Fumarate reductase/succinate dehydrogenase
FT flavoprotein-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02910"
FT REGION 1..46
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 9..23
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 363
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR630664-50"
SQ SEQUENCE 671 AA; 74522 MW; 2A09FB2EA51893D0 CRC64;
MSTQNGKYPE HTEHTEHTQH TEHTEYAAYT TGEPVRDTKA PDGPIADRWD RRRFEAKLVN
PANRRKHTVI VVGTGLAGAA AGATLAEQGY HVVQFCFSDS PRRAHSIAAQ GGINAAKNYR
NDGDSVHRLF YDTVKGGDFR ARESNVHRLA QISVEIIDQC VAQGVPFARE YGGLLDTRSF
GGVQVSRTFY ARGQTGQQLL LGAYQALSRQ IAAGNVELHA RTEMLDLITV DGVARGIVAR
DLVTGSIDTY YADAVVLASG GYGNVFYLST NAMNSNATAV WRAHRRGAYF ANPCFTQIHP
TCIPRTGDHQ SKLTLMSESL RNDGRIWVPK AKGDTRPAAD IPEAERDYYL ERIYPSFGNL
VPRDIASRAA KNVCDEGRGV GPGGQGVYLD FADAIRRMGR DKVAEKYGNL FEMYERITAE
DPYEVPMRIY PAVHYTMGGL WVDYDLQTTV PGLFAIGEAN FSDHGANRLG ASALMQGLGD
GYFVLPSTIN DYLARHPHPE PVDDSHPEAA AAVRETRDCL AKLLAVDGDR TPDSFHREIG
ELMWEYCGMS RTEEGLRKAL ARIPEIREEF WRRIKVPGSG EEFNQSLEKA NRIVDYLELA
ELMCLDALHR AESCGGHFRE ESQTPDGEAA RRDEEFGYAA AWEYRGTGTA PVLHKEDLVF
EYVHPTQRSY A
//
