ID D9W4P6_9ACTN Unreviewed; 378 AA.
AC D9W4P6;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=3-oxoacyl-ACP synthase II {ECO:0000313|EMBL:EFL19874.1};
GN ORFNames=SSNG_07126 {ECO:0000313|EMBL:EFL19874.1};
OS Streptomyces sp. C.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=253839 {ECO:0000313|EMBL:EFL19874.1, ECO:0000313|Proteomes:UP000005763};
RN [1] {ECO:0000313|EMBL:EFL19874.1, ECO:0000313|Proteomes:UP000005763}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C {ECO:0000313|EMBL:EFL19874.1,
RC ECO:0000313|Proteomes:UP000005763};
RG The Broad Institute Genome Sequencing Platform;
RG Broad Institute Microbial Sequencing Center;
RA Fischbach M., Godfrey P., Ward D., Young S., Zeng Q., Koehrsen M.,
RA Alvarado L., Berlin A.M., Bochicchio J., Borenstein D., Chapman S.B.,
RA Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A.,
RA Gujja S., Heilman E.R., Heiman D.I., Hepburn T.A., Howarth C., Jen D.,
RA Larson L., Lewis B., Mehta T., Park D., Pearson M., Richards J.,
RA Roberts A., Saif S., Shea T.D., Shenoy N., Sisk P., Stolte C., Sykes S.N.,
RA Thomson T., Walk T., White J., Yandava C., Straight P., Clardy J., Hung D.,
RA Kolter R., Mekalanos J., Walker S., Walsh C.T., Wieland-Brown L.C.,
RA Haas B., Nusbaum C., Birren B.;
RT "Annotation of Streptomyces sp. strain C.";
RL Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP
CC synthases family. {ECO:0000256|ARBA:ARBA00008467,
CC ECO:0000256|RuleBase:RU003694}.
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DR EMBL; GG657751; EFL19874.1; -; Genomic_DNA.
DR RefSeq; WP_007268799.1; NZ_GG657751.1.
DR AlphaFoldDB; D9W4P6; -.
DR STRING; 253839.SSNG_07126; -.
DR eggNOG; COG0304; Bacteria.
DR HOGENOM; CLU_000022_69_0_11; -.
DR Proteomes; UP000005763; Unassembled WGS sequence.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:UniProt.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProt.
DR Gene3D; 3.40.47.10; -; 1.
DR InterPro; IPR000794; Beta-ketoacyl_synthase.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR11712:SF336; 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11712; POLYKETIDE SYNTHASE-RELATED; 1.
DR Pfam; PF00109; ketoacyl-synt; 1.
DR Pfam; PF02801; Ketoacyl-synt_C; 1.
DR SMART; SM00825; PKS_KS; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS52004; KS3_2; 1.
PE 3: Inferred from homology;
KW Transferase {ECO:0000256|RuleBase:RU003694}.
FT DOMAIN 1..376
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
SQ SEQUENCE 378 AA; 39076 MW; EF7B75F34D022142 CRC64;
MTWDITGMAA VANVGATPGE IFAALCAGRE SRRPLMAFDP DKYRAAYAYE IDDRPKDGGD
IPRRATRWLT TVVRQAVADA GLGEDLSQVP VLVGTTMREQ RSLELWWRDG ADVALEDLHF
GTALQGAFGA STTYTFANAC SATLYALGMA TDMIEAGMAD TVVVAGTDSA TESGFGTLDR
VQNGIPDALR AVDTTHKGML MGEGAAAVVV QRAGTGNGPV HARVRGVSMN CDANHATAPD
PDGITHAVLD AYSRAGVRAR DIDLVMLHGS GTPLNDATES SVLRRIFDSS GPGPRMTAIK
AMTGHTLGGS GLLSLVMAVL AMKEGTVPPV LGLTDPIPEA AGLGLVQGSP AAGDLAIAQI
NAFGFGGINA VAIVEAAR
//
