ID   D9X964_STRVT            Unreviewed;       356 AA.
AC   D9X964;
DT   05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2010, sequence version 1.
DT   27-MAR-2024, entry version 46.
DE   SubName: Full=Hydrogenase expression/formation protein HypE {ECO:0000313|EMBL:EFL30059.1};
GN   ORFNames=SSQG_00577 {ECO:0000313|EMBL:EFL30059.1};
OS   Streptomyces viridochromogenes (strain DSM 40736 / JCM 4977 / BCRC 1201 /
OS   Tue 494).
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=591159 {ECO:0000313|EMBL:EFL30059.1, ECO:0000313|Proteomes:UP000004184};
RN   [1] {ECO:0000313|Proteomes:UP000004184}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 40736 / JCM 4977 / BCRC 1201 / Tue 494
RC   {ECO:0000313|Proteomes:UP000004184};
RG   The Broad Institute Genome Sequencing Platform;
RG   Broad Institute Microbial Sequencing Center;
RA   Fischbach M., Godfrey P., Ward D., Young S., Zeng Q., Koehrsen M.,
RA   Alvarado L., Berlin A.M., Bochicchio J., Borenstein D., Chapman S.B.,
RA   Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A.,
RA   Gujja S., Heilman E.R., Heiman D.I., Hepburn T.A., Howarth C., Jen D.,
RA   Larson L., Lewis B., Mehta T., Park D., Pearson M., Richards J.,
RA   Roberts A., Saif S., Shea T.D., Shenoy N., Sisk P., Stolte C., Sykes S.N.,
RA   Thomson T., Walk T., White J., Yandava C., Straight P., Clardy J., Hung D.,
RA   Kolter R., Mekalanos J., Walker S., Walsh C.T., Wieland-Brown L.C.,
RA   Haas B., Nusbaum C., Birren B.;
RT   "Annotation of Streptomyces viridochromogenes strain DSM 40736.";
RL   Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the HypE family.
CC       {ECO:0000256|ARBA:ARBA00006243}.
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DR   EMBL; GG657757; EFL30059.1; -; Genomic_DNA.
DR   RefSeq; WP_003988169.1; NZ_GG657757.1.
DR   AlphaFoldDB; D9X964; -.
DR   STRING; 591159.SSQG_00577; -.
DR   eggNOG; COG0309; Bacteria.
DR   HOGENOM; CLU_049733_0_0_11; -.
DR   OrthoDB; 9801934at2; -.
DR   Proteomes; UP000004184; Unassembled WGS sequence.
DR   CDD; cd02197; HypE; 1.
DR   Gene3D; 3.90.650.10; PurM-like C-terminal domain; 1.
DR   Gene3D; 3.30.1330.10; PurM-like, N-terminal domain; 1.
DR   InterPro; IPR011854; HypE.
DR   InterPro; IPR010918; PurM-like_C_dom.
DR   InterPro; IPR036676; PurM-like_C_sf.
DR   InterPro; IPR016188; PurM-like_N.
DR   InterPro; IPR036921; PurM-like_N_sf.
DR   NCBIfam; TIGR02124; hypE; 1.
DR   PANTHER; PTHR30303:SF0; CARBAMOYL DEHYDRATASE HYPE; 1.
DR   PANTHER; PTHR30303; HYDROGENASE ISOENZYMES FORMATION PROTEIN HYPE; 1.
DR   Pfam; PF00586; AIRS; 1.
DR   Pfam; PF02769; AIRS_C; 1.
DR   PIRSF; PIRSF005644; Hdrgns_mtr_HypE; 1.
DR   SUPFAM; SSF56042; PurM C-terminal domain-like; 1.
DR   SUPFAM; SSF55326; PurM N-terminal domain-like; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000004184}.
FT   DOMAIN          59..170
FT                   /note="PurM-like N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00586"
FT   DOMAIN          182..328
FT                   /note="PurM-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02769"
SQ   SEQUENCE   356 AA;  36020 MW;  7233AF53AAA1D9FF CRC64;
     MPEQLADVVD PAGWTCPAPL RDQPVVVMGH GGGGALSAEL IEQVFTPAYG NPTLAALADS
     AVLELGGARL AFSTDSYVVR PLFFPGGSLG DLAVNGTVND LAMSGARPAY LSAAFVLEEG
     VELTVVERVA RAMGAAAEAA GVTVATGDTK VVESGHGDGV YVTTAGVGLV PDGVDIRPQR
     ARPGDAVIVS GPIGLHGVAI MSVREGLEFG VEVASDTAPL ADLVAAMLAV TPDIHVLRDP
     TRGGLAASLN EIARASGTGV RLQERAIPVP DAVANACGFL GLEPLYVANE GRLVAFVPPS
     DAEQVLAAMR AHPQGAGATL IGECVAEHPG MVVVATGLGG TRVVDLPLGE QLPRIC
//