ID D9ZIZ8_MALDO Unreviewed; 600 AA.
AC D9ZIZ8;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=Growth-regulating factor {ECO:0000256|RuleBase:RU367127};
GN Name=GRF2 {ECO:0000313|EMBL:ADL36701.1};
OS Malus domestica (Apple) (Pyrus malus).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Rosales; Rosaceae; Amygdaloideae; Maleae; Malus.
OX NCBI_TaxID=3750 {ECO:0000313|EMBL:ADL36701.1};
RN [1] {ECO:0000313|EMBL:ADL36701.1}
RP NUCLEOTIDE SEQUENCE.
RA Hellens A.P., Schulze K., Allan A.C., Storey R.D., Espley R.V., Wang Y.Y.,
RA Nain B., Lo K., Gera E., Wang D., Jamieson K., Karunairetnam S.,
RA Schaffer R., Gleave A.P., Crowhurst R.N., Laing W.A.;
RT "The FruiTFul database; full length cDNAs of apple transcription factors.";
RL Submitted (APR-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ADL36701.1}
RP NUCLEOTIDE SEQUENCE.
RA Allan A.C., Espley R.V., Hellens R.P.;
RT "Transcription Factors in Apple.";
RL Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Transcription activator. {ECO:0000256|RuleBase:RU367127}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU01002, ECO:0000256|RuleBase:RU367127}.
CC -!- DOMAIN: The QLQ domain and WRC domain may be involved in protein-
CC protein interaction and DNA-binding, respectively.
CC {ECO:0000256|RuleBase:RU367127}.
CC -!- SIMILARITY: Belongs to the GRF family. {ECO:0000256|ARBA:ARBA00008122,
CC ECO:0000256|RuleBase:RU367127}.
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DR EMBL; HM122562; ADL36701.1; -; mRNA.
DR AlphaFoldDB; D9ZIZ8; -.
DR EnsemblPlants; mRNA:MD15G0262000; mRNA:MD15G0262000; MD15G0262000.
DR Gramene; mRNA:MD15G0262000; mRNA:MD15G0262000; MD15G0262000.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:UniProtKB-UniRule.
DR GO; GO:0099402; P:plant organ development; IEA:UniProt.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR InterPro; IPR014978; Gln-Leu-Gln_QLQ.
DR InterPro; IPR031137; GRF.
DR InterPro; IPR014977; WRC_dom.
DR PANTHER; PTHR31602:SF42; GROWTH-REGULATING FACTOR 1; 1.
DR PANTHER; PTHR31602; GROWTH-REGULATING FACTOR 5; 1.
DR Pfam; PF08880; QLQ; 1.
DR Pfam; PF08879; WRC; 1.
DR SMART; SM00951; QLQ; 1.
DR PROSITE; PS51666; QLQ; 1.
DR PROSITE; PS51667; WRC; 1.
PE 2: Evidence at transcript level;
KW Activator {ECO:0000256|RuleBase:RU367127};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU01002}; Transcription {ECO:0000256|RuleBase:RU367127};
KW Transcription regulation {ECO:0000256|RuleBase:RU367127}.
FT DOMAIN 157..192
FT /note="QLQ"
FT /evidence="ECO:0000259|PROSITE:PS51666"
FT DOMAIN 222..266
FT /note="WRC"
FT /evidence="ECO:0000259|PROSITE:PS51667"
FT REGION 1..66
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 252..298
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOTIF 227..237
FT /note="Bipartite nuclear localization signal"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01002"
FT MOTIF 255..262
FT /note="Bipartite nuclear localization signal"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01002"
FT COMPBIAS 46..60
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 269..298
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 600 AA; 64887 MW; CFB507CF6B581EA3 CRC64;
MAEVSGMDFG LMGLEGLVGP EAGGGEAAGK VGDGSGSASA KQQRSWPVDD DWRTSKMPKN
EDLNASRTMP LQYQGTPLLR SNSQLLPPPA ETHRQEQMLS FSNNKSEVSF LSKDGDFAYY
QRNPTPILSP YPRNAGSPGY GSLNLSMHGP LTGARGPFTP SQWIELEHQA LIYKYMTSNV
PVPSNLLIPL KKPLYPYGLS GPSNPTSIAW GAYHLGFSGN NDPEPGRCRR TDGKKWRCSR
DAVADQKYCE RHINRGRHRS RKPVEGQPGQ AVSGTSNSKR VPMNSSMSTS VMASNGASNS
ITTAPQQFKR LQTAVAANPS SADAFVNRMQ DPRGLSVMSA PTLKPKSNNS TSKLGKQEFL
VEESSQSEFG IVSTYSLLNP SHRNSYISKD FGGSFLDFSD QETQDQHPLR QFMDDWPKDQ
SSHSVSTWPE EIKSDWTQLS MSIPMASSEF SSSSSSPTHE KLALSPLRLS REFVPAQMNL
GMSNDLSESI QKQTNWIPIP WGNSMGGPLG EVITNTTSSG KICNNSTSPL NLLNEGWDGN
SQLGSSPTGV LQKSTFCSLS NSSSGSSPRG GEIKKSSLDG ASIYDDVLGS TFASSPVPSL
//
