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Database: UniProt
Entry: DNAA_ARCB4
LinkDB: DNAA_ARCB4
Original site: DNAA_ARCB4 
ID   DNAA_ARCB4              Reviewed;         438 AA.
AC   A8EQT0;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   13-NOV-2007, sequence version 1.
DT   25-OCT-2017, entry version 62.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000255|HAMAP-Rule:MF_00377};
GN   Name=dnaA {ECO:0000255|HAMAP-Rule:MF_00377};
GN   OrderedLocusNames=Abu_0001;
OS   Arcobacter butzleri (strain RM4018).
OC   Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales;
OC   Campylobacteraceae; Arcobacter.
OX   NCBI_TaxID=367737;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RM4018;
RX   PubMed=18159241; DOI=10.1371/journal.pone.0001358;
RA   Miller W.G., Parker C.T., Rubenfield M., Mendz G.L., Woesten M.M.S.M.,
RA   Ussery D.W., Stolz J.F., Binnewies T.T., Hallin P.F., Wang G.,
RA   Malek J.A., Rogosin A., Stanker L.H., Mandrell R.E.;
RT   "The complete genome sequence and analysis of the
RT   Epsilonproteobacterium Arcobacter butzleri.";
RL   PLoS ONE 2:E1358-E1358(2007).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000255|HAMAP-
CC       Rule:MF_00377}.
DR   EMBL; CP000361; ABV66286.1; -; Genomic_DNA.
DR   RefSeq; WP_012011924.1; NC_009850.1.
DR   ProteinModelPortal; A8EQT0; -.
DR   SMR; A8EQT0; -.
DR   STRING; 367737.Abu_0001; -.
DR   EnsemblBacteria; ABV66286; ABV66286; Abu_0001.
DR   GeneID; 24304941; -.
DR   KEGG; abu:Abu_0001; -.
DR   eggNOG; ENOG4105CI4; Bacteria.
DR   eggNOG; COG0593; LUCA.
DR   HOGENOM; HOG000235658; -.
DR   KO; K02313; -.
DR   OMA; VENWVKD; -.
DR   OrthoDB; POG091H02FF; -.
DR   Proteomes; UP000001136; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:InterPro.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA replication;
KW   DNA-binding; Nucleotide-binding; Reference proteome.
FT   CHAIN         1    438       Chromosomal replication initiator protein
FT                                DnaA.
FT                                /FTId=PRO_1000060008.
FT   NP_BIND     142    149       ATP. {ECO:0000255|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   438 AA;  50088 MW;  A523987746AA6460 CRC64;
     MTTKEFLTII QKEANQIDYE RYLKQLVYKK VSSDNKIAIF EVNNKYIASW IKSKFTNLIQ
     HCFEIYDGSK PTIEIKLSNE KKSKKEILKE QTQNESTEST ILNPSYTFDS FVVGPSNQMA
     YNASLAVANK PGIQYNPLFI YGGTGLGKTH LLQAVGNHAI EKGNTVIYVT IEQFMNDFTF
     SIKNKNMEHF RNKYRKCDVL LIDDIQFLSG KEQTQEEFFH TFNELHNAKK QIVMTSDRLP
     SQIAGLVDRL KSRFEWGLTA DVQIPGLETK IAIIEKKSEL NGICLSREII NFIATNLDNS
     IREIEGVLIR INASASLLNQ EITLPMVQGL LKEQIKETKE NVKLPDIINI VANQLNIKPS
     DIKSKKRTAT VANARRIVIY LVRELTHNSM PDIAKFLGMK DHSAISHNIK KANELIEKDE
     NFKLIIENLK NKIINSRE
//
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