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Database: UniProt
Entry: DNAA_AROAE
LinkDB: DNAA_AROAE
Original site: DNAA_AROAE 
ID   DNAA_AROAE              Reviewed;         481 AA.
AC   Q5P4P0;
DT   19-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT   04-JAN-2005, sequence version 1.
DT   07-JUN-2017, entry version 80.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000255|HAMAP-Rule:MF_00377};
GN   Name=dnaA {ECO:0000255|HAMAP-Rule:MF_00377};
GN   OrderedLocusNames=AZOSEA15970; ORFNames=ebA2846;
OS   Aromatoleum aromaticum (strain EbN1) (Azoarcus sp. (strain EbN1)).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Rhodocyclales;
OC   Rhodocyclaceae; Aromatoleum.
OX   NCBI_TaxID=76114;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=EbN1;
RX   PubMed=15551059; DOI=10.1007/s00203-004-0742-9;
RA   Rabus R., Kube M., Heider J., Beck A., Heitmann K., Widdel F.,
RA   Reinhardt R.;
RT   "The genome sequence of an anaerobic aromatic-degrading denitrifying
RT   bacterium, strain EbN1.";
RL   Arch. Microbiol. 183:27-36(2005).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000255|HAMAP-
CC       Rule:MF_00377}.
DR   EMBL; CR555306; CAI07722.1; -; Genomic_DNA.
DR   RefSeq; WP_011237436.1; NC_006513.1.
DR   ProteinModelPortal; Q5P4P0; -.
DR   SMR; Q5P4P0; -.
DR   STRING; 76114.ebA2846; -.
DR   EnsemblBacteria; CAI07722; CAI07722; ebA2846.
DR   KEGG; eba:ebA2846; -.
DR   eggNOG; ENOG4105CI4; Bacteria.
DR   eggNOG; COG0593; LUCA.
DR   HOGENOM; HOG000235659; -.
DR   KO; K02313; -.
DR   OMA; REFNPLF; -.
DR   OrthoDB; POG091H02FF; -.
DR   Proteomes; UP000006552; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:InterPro.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA replication;
KW   DNA-binding; Nucleotide-binding; Reference proteome.
FT   CHAIN         1    481       Chromosomal replication initiator protein
FT                                DnaA.
FT                                /FTId=PRO_0000114123.
FT   NP_BIND     186    193       ATP. {ECO:0000255|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   481 AA;  53725 MW;  6FD2DBBDF7EB1753 CRC64;
     MSQDLWSFCL SRLEHELPPQ QFNTWIKTLQ ADEEKAGASV ALRLVAPSRF VLQWVRERYL
     RRIGELGAEF HGAPIEIELV LPAAGAARPA ARPVIGSGPV AGPAPAPTPS QAPAATAAAP
     AVVTRPAEPE SSIVTASDLA YEKTRLNADF TFDTLVTGRA NDLARAAAMQ VAQNPGTSYN
     PLFVYGGVGL GKTHLVHAIG NAVYRHNPRA VIRYVHVEDY YADVVRAYQQ KSFDAFKRYY
     RSLDLLLIDD IQFFNNKNRT QEEFFHAFNA LTEARKQIVI TCDTYPKDIQ GLEDRLISRF
     DWGLTVQIEP PELEMRVAIL QKKAEALRVD LHDDVAFLIA KNLRSNVREL EGALNKVVAF
     ARFHGRGITL EVAKDALKDL LNAHNRQLTI EHIQKTVADY YKIKVADMHS KKRTRVIARP
     RQVAMWLAKD LTPMSLPAIG EAFGGRDHTT VMHACRTIAE LRLGDHQLNH DVHVLTQVLR
     G
//
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