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Database: UniProt
Entry: DNAA_AZOSB
LinkDB: DNAA_AZOSB
Original site: DNAA_AZOSB 
ID   DNAA_AZOSB              Reviewed;         480 AA.
AC   A1K1B4;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   06-FEB-2007, sequence version 1.
DT   30-AUG-2017, entry version 65.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000255|HAMAP-Rule:MF_00377};
GN   Name=dnaA {ECO:0000255|HAMAP-Rule:MF_00377};
GN   OrderedLocusNames=azo0001;
OS   Azoarcus sp. (strain BH72).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Rhodocyclales;
OC   Zoogloeaceae; Azoarcus.
OX   NCBI_TaxID=62928;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BH72;
RX   PubMed=17057704; DOI=10.1038/nbt1243;
RA   Krause A., Ramakumar A., Bartels D., Battistoni F., Bekel T., Boch J.,
RA   Boehm M., Friedrich F., Hurek T., Krause L., Linke B., McHardy A.C.,
RA   Sarkar A., Schneiker S., Syed A.A., Thauer R., Vorhoelter F.-J.,
RA   Weidner S., Puehler A., Reinhold-Hurek B., Kaiser O., Goesmann A.;
RT   "Complete genome of the mutualistic, N2-fixing grass endophyte
RT   Azoarcus sp. strain BH72.";
RL   Nat. Biotechnol. 24:1385-1391(2006).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000255|HAMAP-
CC       Rule:MF_00377}.
DR   EMBL; AM406670; CAL92619.1; -; Genomic_DNA.
DR   RefSeq; WP_011763738.1; NC_008702.1.
DR   ProteinModelPortal; A1K1B4; -.
DR   SMR; A1K1B4; -.
DR   STRING; 62928.azo0001; -.
DR   EnsemblBacteria; CAL92619; CAL92619; azo0001.
DR   KEGG; azo:azo0001; -.
DR   eggNOG; ENOG4105CI4; Bacteria.
DR   eggNOG; COG0593; LUCA.
DR   HOGENOM; HOG000235659; -.
DR   KO; K02313; -.
DR   OMA; REFNPLF; -.
DR   OrthoDB; POG091H02FF; -.
DR   Proteomes; UP000002588; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:InterPro.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA replication;
KW   DNA-binding; Nucleotide-binding; Reference proteome.
FT   CHAIN         1    480       Chromosomal replication initiator protein
FT                                DnaA.
FT                                /FTId=PRO_1000048605.
FT   NP_BIND     185    192       ATP. {ECO:0000255|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   480 AA;  54044 MW;  BCEF2B5CD02EF936 CRC64;
     MNQDFWPFCL ARLEQELPQQ QFNTWIKTLQ AAESDADGAV ALTLTAPNRF VLQWVRERYM
     RRIGELGEEF HGQPIQLELQ LPVAGAKSAP VAPARVRPAG ANGGAAANSP MAPPVSEAAP
     PQIIVRPSEP EPVSANELAY DKTRLNADFT FDTLVTGRAN DLARAAAMQV AQNPGTSYNP
     LFVYGGVGLG KTHLVHAIGN AVYRHNPRMV IRYVHVEDYY ADVVRAYQQK SFDAFKRYYR
     SLDMLIIDDI QFFNNKNRTQ EEFFHAFNAL TEAKKQIVIT CDTYPKDIQG LEDRLISRFD
     WGLTVQIEPP ELEMRVAILQ KKAEALRVSV DDDVAFLIAK NLRSNVRELE GALNKVVAYA
     RFHGRGISLE VAKEALKDLL HAHNRQLSIE HIQKTVADYY KIKVADMHSK KRTRVIARPR
     QVAMWLAKEL TPMSLPAIGE AFGGRDHTTV LHACRTITEL RLGDHQLNHD VHVLTQVLRG
//
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