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Database: UniProt
Entry: DNAA_BACSK
LinkDB: DNAA_BACSK
Original site: DNAA_BACSK 
ID   DNAA_BACSK              Reviewed;         451 AA.
AC   Q5WM31;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   07-JUN-2017, entry version 83.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000255|HAMAP-Rule:MF_00377};
GN   Name=dnaA {ECO:0000255|HAMAP-Rule:MF_00377};
GN   OrderedLocusNames=ABC0001;
OS   Bacillus clausii (strain KSM-K16).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=66692;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KSM-K16;
RA   Takaki Y., Kageyama Y., Shimamura S., Suzuki H., Nishi S., Hatada Y.,
RA   Kawai S., Ito S., Horikoshi K.;
RT   "The complete genome sequence of the alkaliphilic Bacillus clausii
RT   KSM-K16.";
RL   Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000255|HAMAP-
CC       Rule:MF_00377}.
DR   EMBL; AP006627; BAD62544.1; -; Genomic_DNA.
DR   RefSeq; WP_011244865.1; NC_006582.1.
DR   ProteinModelPortal; Q5WM31; -.
DR   SMR; Q5WM31; -.
DR   STRING; 66692.ABC0001; -.
DR   EnsemblBacteria; BAD62544; BAD62544; ABC0001.
DR   KEGG; bcl:ABC0001; -.
DR   eggNOG; ENOG4105CI4; Bacteria.
DR   eggNOG; COG0593; LUCA.
DR   HOGENOM; HOG000235658; -.
DR   KO; K02313; -.
DR   OMA; REFNPLF; -.
DR   OrthoDB; POG091H02FF; -.
DR   Proteomes; UP000001168; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:InterPro.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA replication;
KW   DNA-binding; Nucleotide-binding; Reference proteome.
FT   CHAIN         1    451       Chromosomal replication initiator protein
FT                                DnaA.
FT                                /FTId=PRO_0000114132.
FT   NP_BIND     155    162       ATP. {ECO:0000255|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   451 AA;  51183 MW;  E303991496BED5D6 CRC64;
     MENIDDLWNK VLEEMKKKVS KPSYETWLRA TKANALQNND TIIVTAPNEF ARDWLEDHYS
     GLTSDIIEQL TGARLTPKFV IPQHNQEEEA LPEQTPQTPP EKDVAGQSTL SQTMLNDKYT
     FNTFVIGSGN RFAHAASLAV AEAPARAYNP LFIYGGVGLG KTHLMHAIGH YVMEHNPNAK
     VVYLSSEKFT NEFINAIRDN KAVHFRNKYR NVDVLLIDDI QFIAGKIQTQ EEFFHTFNAL
     HEESKQIVIS SDRPPKEIPT LEDRLRSRFE WGLITDITPP DLETRIAILR KKAKAENLDI
     PNEVMLYIAN QIDTNIRELE GALIRVVAYS SLINQDMNAD LAAEALKDII PNAMPKTLTI
     TDIQKLVGEH FQVKLEDFKA KKRTKSVAFP RQIAMYLSRE MTDASLPKIG SEFGGRDHTT
     VIHAHEKISK LLATDQELQQ KVQAITEQLR Q
//
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