GenomeNet

Database: UniProt
Entry: DNAA_BORT9
LinkDB: DNAA_BORT9
Original site: DNAA_BORT9 
ID   DNAA_BORT9              Reviewed;         484 AA.
AC   A1QZM2;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   14-APR-2009, sequence version 1.
DT   07-JUN-2017, entry version 57.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000255|HAMAP-Rule:MF_00377};
GN   Name=dnaA {ECO:0000255|HAMAP-Rule:MF_00377}; OrderedLocusNames=BT0437;
OS   Borrelia turicatae (strain 91E135).
OC   Bacteria; Spirochaetes; Spirochaetales; Borreliaceae; Borrelia.
OX   NCBI_TaxID=314724;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=91E135;
RA   Porcella S.F., Raffel S.J., Schrumpf M.E., Montgomery B., Smith T.,
RA   Schwan T.G.;
RT   "The genome sequence of Borrelia hermsii and Borrelia turicatae:
RT   comparative analysis of two agents of endemic N. America relapsing
RT   fever.";
RL   Submitted (DEC-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000255|HAMAP-
CC       Rule:MF_00377}.
DR   EMBL; CP000049; AAX17764.1; -; Genomic_DNA.
DR   RefSeq; WP_011772383.1; NC_008710.1.
DR   SMR; A1QZM2; -.
DR   STRING; 314724.BT0437; -.
DR   EnsemblBacteria; AAX17764; AAX17764; BT0437.
DR   KEGG; btu:BT0437; -.
DR   eggNOG; ENOG4105CI4; Bacteria.
DR   eggNOG; COG0593; LUCA.
DR   HOGENOM; HOG000235658; -.
DR   KO; K02313; -.
DR   OMA; REFNPLF; -.
DR   OrthoDB; POG091H02FF; -.
DR   Proteomes; UP000001205; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:InterPro.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA replication;
KW   DNA-binding; Nucleotide-binding; Reference proteome.
FT   CHAIN         1    484       Chromosomal replication initiator protein
FT                                DnaA.
FT                                /FTId=PRO_1000189784.
FT   NP_BIND     182    189       ATP. {ECO:0000255|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   484 AA;  56342 MW;  148F87F85713FCFA CRC64;
     MQEGKNIWSL ILAAIRKELS EEEFYIWFEN LYFIDATDES IKISAPNSFH KNQVEKRFSK
     RIKEILTEKG HNTINVEFIN PPKEPKTHSM ELKNTSLKDI SIQQDSPEKR TILNTHTKNI
     IEHTKHYVIK EDIHTKYRNP FLKKKYTFEN FIIGPNNKLA YNASLSIAKN PGKKYNPCLI
     YGGVGLGKTH LLQSIGNKTE ELHKEFKILY VTAENFLNEF VESIKTNETK RFKKKYRHLD
     MLLIDDIHDL QKKEGIQEEL FHTFNALYED NKQMVFTCDR QPSELINFTD RLKSRFTRGL
     NVDISKPNFE LRVAIIEKKA EEDGIKVPKN ILNLVAKKVT TNIRDLEAAV TKLKAHIDLE
     DIEIDTSIVD KIIKEIIAYE NDKTNTNNTI NIESIKKVIL RELKLTNKDI EGNSKKPEIT
     KARHIYAYLL RNFTELSTIE IGKIIGGKTH STVLYSINKI DKERNNDLEI NNLIIELMNK
     INKN
//
DBGET integrated database retrieval system