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Database: UniProt
Entry: DNAA_BRADU
LinkDB: DNAA_BRADU
Original site: DNAA_BRADU 
ID   DNAA_BRADU              Reviewed;         470 AA.
AC   Q89W63;
DT   07-NOV-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   25-OCT-2017, entry version 89.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000255|HAMAP-Rule:MF_00377};
GN   Name=dnaA {ECO:0000255|HAMAP-Rule:MF_00377};
GN   OrderedLocusNames=bll0830;
OS   Bradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC
OS   14792 / USDA 110).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Bradyrhizobiaceae; Bradyrhizobium.
OX   NCBI_TaxID=224911;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110;
RX   PubMed=12597275; DOI=10.1093/dnares/9.6.189;
RA   Kaneko T., Nakamura Y., Sato S., Minamisawa K., Uchiumi T.,
RA   Sasamoto S., Watanabe A., Idesawa K., Iriguchi M., Kawashima K.,
RA   Kohara M., Matsumoto M., Shimpo S., Tsuruoka H., Wada T., Yamada M.,
RA   Tabata S.;
RT   "Complete genomic sequence of nitrogen-fixing symbiotic bacterium
RT   Bradyrhizobium japonicum USDA110.";
RL   DNA Res. 9:189-197(2002).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000255|HAMAP-
CC       Rule:MF_00377}.
DR   EMBL; BA000040; BAC46095.1; -; Genomic_DNA.
DR   RefSeq; NP_767470.1; NC_004463.1.
DR   RefSeq; WP_011083652.1; NZ_CP011360.1.
DR   ProteinModelPortal; Q89W63; -.
DR   SMR; Q89W63; -.
DR   STRING; 224911.bll0830; -.
DR   EnsemblBacteria; BAC46095; BAC46095; BAC46095.
DR   GeneID; 1048791; -.
DR   KEGG; bja:bll0830; -.
DR   PATRIC; fig|224911.44.peg.207; -.
DR   eggNOG; ENOG4105CI4; Bacteria.
DR   eggNOG; COG0593; LUCA.
DR   HOGENOM; HOG000235660; -.
DR   InParanoid; Q89W63; -.
DR   KO; K02313; -.
DR   OMA; REFNPLF; -.
DR   OrthoDB; POG091H02FF; -.
DR   PhylomeDB; Q89W63; -.
DR   Proteomes; UP000002526; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003688; F:DNA replication origin binding; IBA:GO_Central.
DR   GO; GO:0006270; P:DNA replication initiation; IBA:GO_Central.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA replication;
KW   DNA-binding; Nucleotide-binding; Reference proteome.
FT   CHAIN         1    470       Chromosomal replication initiator protein
FT                                DnaA.
FT                                /FTId=PRO_0000114144.
FT   NP_BIND     171    178       ATP. {ECO:0000255|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   470 AA;  52410 MW;  DCD2FC0EB5A80066 CRC64;
     MNTSEQDRWS RVKGRLRSSV GEDIYTSWFA RMDLEDVQDE SVRLSVPTRF LKSWIQAHYA
     ERVLSCWQAE MPEVHRIDLT VRSAVRPVAP PKEAPAPVET RRAPAPELRS TATAPVSANH
     DALGGSPLDP RLTFASFVIG RSNTLAHAAA RQVAEGRRGD PVMFNPLYIH AGVGLGKTHL
     LQAVTWAGNS GNERKVLYLT AEKFMYGFVA ALKTQTALAF KEALRGIDVL VIDDLQFLQG
     KSTQAEFCHT LNALIDAGRQ VVIAADRPPS DLESLDDRVR SRLAGGLVVE MGSLGEELRH
     GILKSRVAAA RAHHATFDVP EEVLHYLART ITHNGRDLEG AINRLLAHSK LNNQPVTLEM
     AEREVRDLVR PQEPKRIKIE DIQRVVARQY NVSRSDLLSS RRTANVVRPR QVAMYLAKTL
     TLRSLPEIGR RFGGRDHTTV LHAVRKIEAL VSKDTALSEE VESLKRQLQE
//
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