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Database: UniProt
Entry: DNAA_CHLAA
LinkDB: DNAA_CHLAA
Original site: DNAA_CHLAA 
ID   DNAA_CHLAA              Reviewed;         479 AA.
AC   A9WAN1;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-FEB-2008, sequence version 1.
DT   07-JUN-2017, entry version 65.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000255|HAMAP-Rule:MF_00377};
GN   Name=dnaA {ECO:0000255|HAMAP-Rule:MF_00377};
GN   OrderedLocusNames=Caur_0001;
OS   Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl).
OC   Bacteria; Chloroflexi; Chloroflexia; Chloroflexales; Chloroflexineae;
OC   Chloroflexaceae; Chloroflexus.
OX   NCBI_TaxID=324602;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29366 / DSM 635 / J-10-fl;
RX   PubMed=21714912; DOI=10.1186/1471-2164-12-334;
RA   Tang K.H., Barry K., Chertkov O., Dalin E., Han C.S., Hauser L.J.,
RA   Honchak B.M., Karbach L.E., Land M.L., Lapidus A., Larimer F.W.,
RA   Mikhailova N., Pitluck S., Pierson B.K., Blankenship R.E.;
RT   "Complete genome sequence of the filamentous anoxygenic phototrophic
RT   bacterium Chloroflexus aurantiacus.";
RL   BMC Genomics 12:334-334(2011).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000255|HAMAP-
CC       Rule:MF_00377}.
DR   EMBL; CP000909; ABY33259.1; -; Genomic_DNA.
DR   RefSeq; WP_012255915.1; NC_010175.1.
DR   RefSeq; YP_001633648.1; NC_010175.1.
DR   ProteinModelPortal; A9WAN1; -.
DR   SMR; A9WAN1; -.
DR   STRING; 324602.Caur_0001; -.
DR   EnsemblBacteria; ABY33259; ABY33259; Caur_0001.
DR   GeneID; 5825775; -.
DR   KEGG; cau:Caur_0001; -.
DR   PATRIC; fig|324602.8.peg.1; -.
DR   eggNOG; ENOG4105CI4; Bacteria.
DR   eggNOG; COG0593; LUCA.
DR   HOGENOM; HOG000235658; -.
DR   InParanoid; A9WAN1; -.
DR   KO; K02313; -.
DR   OMA; REFNPLF; -.
DR   OrthoDB; POG091H02FF; -.
DR   Proteomes; UP000002008; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003688; F:DNA replication origin binding; IBA:GO_Central.
DR   GO; GO:0006270; P:DNA replication initiation; IBA:GO_Central.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA replication;
KW   DNA-binding; Nucleotide-binding; Reference proteome.
FT   CHAIN         1    479       Chromosomal replication initiator protein
FT                                DnaA.
FT                                /FTId=PRO_1000079942.
FT   NP_BIND     180    187       ATP. {ECO:0000255|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   479 AA;  53290 MW;  EDA56BC63BA4B8D4 CRC64;
     MNLTQIWKAT LSALQTQTSR HDYEALLRPA TLLSLDNGAA FIGVSSPGQK EGLENRLLMP
     LRNALARVVG YPVQVQVLIA NLNSRTEPSP SLTLSNGSRL MSDPEPVVAE TPAPALTPGN
     GTGERVVQLD LASAMRSGML NPRYTFSSFI VGSSNRLAHA ACLAVADNPG QAYNPLFLYG
     GVGLGKTHLL HAIGNRVLDR DPEINVLYVS SEKFTNDLIN AIRRQQTEEF RMRYRNIDVL
     LIDDIQFIAG KDATQEEFFH TFNTLHSAAK HIVISSDRPP KAILTLEERL RSRFEWGLIV
     DVQPPDLETR TAILRAKAEQ MSVHVPDEVI DFLAHKIQSN IRELEGSLNR VAAYAELNRA
     PITIETATAA LADLLGNQRR RRISAEAILQ IVSEHYGIEV EQLRARNRSR HVVVPRQVAM
     YLLREETESS LVDIGNLLGG RDHTTVMYGC EKIAEEINSD SRLRSEVMAI RERIQMLRG
//
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