GenomeNet

Database: UniProt
Entry: DNAA_CLAMS
LinkDB: DNAA_CLAMS
Original site: DNAA_CLAMS 
ID   DNAA_CLAMS              Reviewed;         476 AA.
AC   B0RH69;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   08-APR-2008, sequence version 1.
DT   25-OCT-2017, entry version 66.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000255|HAMAP-Rule:MF_00377};
GN   Name=dnaA {ECO:0000255|HAMAP-Rule:MF_00377};
GN   OrderedLocusNames=CMS0001;
OS   Clavibacter michiganensis subsp. sepedonicus (strain ATCC 33113 / DSM
OS   20744 / JCM 9667 / LMG 2889 / C-1) (Corynebacterium sepedonicum).
OC   Bacteria; Actinobacteria; Micrococcales; Microbacteriaceae;
OC   Clavibacter.
OX   NCBI_TaxID=31964;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 33113 / DSM 20744 / JCM 9667 / LMG 2889 / C-1;
RX   PubMed=18192393; DOI=10.1128/JB.01598-07;
RA   Bentley S.D., Corton C., Brown S.E., Barron A., Clark L., Doggett J.,
RA   Harris B., Ormond D., Quail M.A., May G., Francis D., Knudson D.,
RA   Parkhill J., Ishimaru C.A.;
RT   "Genome of the actinomycete plant pathogen Clavibacter michiganensis
RT   subsp. sepedonicus suggests recent niche adaptation.";
RL   J. Bacteriol. 190:2150-2160(2008).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000255|HAMAP-
CC       Rule:MF_00377}.
DR   EMBL; AM849034; CAQ00127.1; -; Genomic_DNA.
DR   RefSeq; WP_012297496.1; NC_010407.1.
DR   ProteinModelPortal; B0RH69; -.
DR   SMR; B0RH69; -.
DR   STRING; 31964.CMS_0001; -.
DR   PRIDE; B0RH69; -.
DR   EnsemblBacteria; CAQ00127; CAQ00127; CMS0001.
DR   GeneID; 29472540; -.
DR   KEGG; cms:CMS0001; -.
DR   eggNOG; ENOG4105CI4; Bacteria.
DR   eggNOG; COG0593; LUCA.
DR   KO; K02313; -.
DR   OMA; REFNPLF; -.
DR   OrthoDB; POG091H02FF; -.
DR   Proteomes; UP000001318; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:InterPro.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA replication;
KW   DNA-binding; Nucleotide-binding; Reference proteome.
FT   CHAIN         1    476       Chromosomal replication initiator protein
FT                                DnaA.
FT                                /FTId=PRO_1000079943.
FT   NP_BIND     173    180       ATP. {ECO:0000255|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   476 AA;  53079 MW;  2A29B27AE1840213 CRC64;
     MSDRSDPTHA IWQKVLAALT ADDRITPQLH GFISLVEPKG VMTGTLYLEV PNDLTRGMLE
     QRIRVPLLNA IGSLDEAAGV SNFAIVVNPG IAQDAFAQHP EPAEQPYIET PTITAPTDNP
     GLPASPSRGD SRLNPKYGFD TFVIGGSNRF AHAAAVAVAE APAKAYNPLF IYGDSGLGKT
     HLLHAIGHYA ISLYPGIRVR YVSSEEFTND FINSIANNRS SLFQSRYRDN DILLIDDIQF
     LQGKDSTQEA FFHTFNTLHD HNKQVVITSD LPPKHLTGFE DRMRSRFEWG LITDVQAPDL
     ETRIAILRKK AQSEKLQVPD DILEYMATKV TSNIRELEGT LIRVTAFASL NKTPVDLALV
     QTVLKDLITL DEDNVIAPVD IINHTAAYFK LTVDDLYGSS RSQAVATARQ IAMYLCRELT
     NLSLPKIGQL FGNRDHTTVM YANKKITELM KERRSIYNQV TELTSRIKQN HRYGKM
//
DBGET integrated database retrieval system