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Database: UniProt
Entry: DNAA_CYAP4
LinkDB: DNAA_CYAP4
Original site: DNAA_CYAP4 
ID   DNAA_CYAP4              Reviewed;         460 AA.
AC   B8HRT5;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   03-MAR-2009, sequence version 1.
DT   25-OCT-2017, entry version 51.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000255|HAMAP-Rule:MF_00377};
GN   Name=dnaA {ECO:0000255|HAMAP-Rule:MF_00377};
GN   OrderedLocusNames=Cyan7425_0198;
OS   Cyanothece sp. (strain PCC 7425 / ATCC 29141).
OC   Bacteria; Cyanobacteria; Oscillatoriophycideae; Oscillatoriales;
OC   Cyanothecaceae; Cyanothece.
OX   NCBI_TaxID=395961;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 7425 / ATCC 29141;
RX   PubMed=21972240; DOI=10.1128/mBio.00214-11;
RA   Bandyopadhyay A., Elvitigala T., Welsh E., Stockel J., Liberton M.,
RA   Min H., Sherman L.A., Pakrasi H.B.;
RT   "Novel metabolic attributes of the genus Cyanothece, comprising a
RT   group of unicellular nitrogen-fixing Cyanobacteria.";
RL   MBio 2:E214-E214(2011).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000255|HAMAP-
CC       Rule:MF_00377}.
DR   EMBL; CP001344; ACL42594.1; -; Genomic_DNA.
DR   RefSeq; WP_012625696.1; NC_011884.1.
DR   ProteinModelPortal; B8HRT5; -.
DR   SMR; B8HRT5; -.
DR   STRING; 395961.Cyan7425_0198; -.
DR   EnsemblBacteria; ACL42594; ACL42594; Cyan7425_0198.
DR   KEGG; cyn:Cyan7425_0198; -.
DR   eggNOG; ENOG4105CI4; Bacteria.
DR   eggNOG; COG0593; LUCA.
DR   HOGENOM; HOG000235658; -.
DR   KO; K02313; -.
DR   OMA; REFNPLF; -.
DR   OrthoDB; POG091H02FF; -.
DR   Proteomes; UP000002511; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:InterPro.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA replication;
KW   DNA-binding; Nucleotide-binding; Reference proteome.
FT   CHAIN         1    460       Chromosomal replication initiator protein
FT                                DnaA.
FT                                /FTId=PRO_1000189794.
FT   NP_BIND     160    167       ATP. {ECO:0000255|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   460 AA;  51998 MW;  3410CEC1DF011BA7 CRC64;
     MDISLESLWN QILERLQLQL SRPTFETWIK TATAEAFTED RLTIRTPNPF ARNWIQKYYL
     KTIADVAHDI LGHPVDVQLV IAEGEETPSS EETDLGFAFP PLFRNPSPAP APQRERMSDL
     NPKYVFSRYV VGPNNRMAHA ACLAVAESPG REFNPLFLCG GVGLGKTHLM QAIGHYRLEI
     CPDSKIFYVS TEQFTNDLIA AIRKDSMQSF REHYRAVDVM LVDDIQFIEG KEYTQEEFFH
     TFNTLHEAGK QVVLASDRPP SQIPRLQERL CSRFSMGLIA DIQPPDLETR MAILQKKAEY
     ENIRLPREVI EYIASSYTSN IRELEGALIR AVAYISISGL PMTVENIAPV LTPTTAKLEA
     SPQTILLAVS DTFGIPIEDL KGNSRRREIS VARQVGMYLM RQHTGLSLPK IGEEFGGKDH
     TTVLYSCEKV ADLQRTDPEI AQTLRQLSDR INLASRQTEN
//
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