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Database: UniProt
Entry: DNAA_CYAP8
LinkDB: DNAA_CYAP8
Original site: DNAA_CYAP8 
ID   DNAA_CYAP8              Reviewed;         453 AA.
AC   B7JYF1;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   10-FEB-2009, sequence version 1.
DT   07-JUN-2017, entry version 54.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000255|HAMAP-Rule:MF_00377};
GN   Name=dnaA {ECO:0000255|HAMAP-Rule:MF_00377};
GN   OrderedLocusNames=PCC8801_0003;
OS   Cyanothece sp. (strain PCC 8801) (Synechococcus sp. (strain PCC 8801 /
OS   RF-1)).
OC   Bacteria; Cyanobacteria; Oscillatoriophycideae; Oscillatoriales;
OC   Cyanothecaceae; Cyanothece.
OX   NCBI_TaxID=41431;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 8801;
RX   PubMed=21972240; DOI=10.1128/mBio.00214-11;
RA   Bandyopadhyay A., Elvitigala T., Welsh E., Stockel J., Liberton M.,
RA   Min H., Sherman L.A., Pakrasi H.B.;
RT   "Novel metabolic attributes of the genus Cyanothece, comprising a
RT   group of unicellular nitrogen-fixing Cyanobacteria.";
RL   MBio 2:E214-E214(2011).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000255|HAMAP-
CC       Rule:MF_00377}.
DR   EMBL; CP001287; ACK64110.1; -; Genomic_DNA.
DR   RefSeq; WP_012593387.1; NC_011726.1.
DR   ProteinModelPortal; B7JYF1; -.
DR   SMR; B7JYF1; -.
DR   STRING; 41431.PCC8801_0003; -.
DR   EnsemblBacteria; ACK64110; ACK64110; PCC8801_0003.
DR   KEGG; cyp:PCC8801_0003; -.
DR   eggNOG; ENOG4105CI4; Bacteria.
DR   eggNOG; COG0593; LUCA.
DR   HOGENOM; HOG000235658; -.
DR   KO; K02313; -.
DR   OMA; REFNPLF; -.
DR   OrthoDB; POG091H02FF; -.
DR   Proteomes; UP000008204; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:InterPro.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA replication;
KW   DNA-binding; Nucleotide-binding; Reference proteome.
FT   CHAIN         1    453       Chromosomal replication initiator protein
FT                                DnaA.
FT                                /FTId=PRO_1000121970.
FT   NP_BIND     154    161       ATP. {ECO:0000255|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   453 AA;  51592 MW;  83DA1756F71FABF5 CRC64;
     MNISPQYLWN QVLERLQIRL TRPAFETWIQ DATVQEWKDN CLVIQVANSF ILNHLQKTYQ
     PIIAQEVASV VGYPVDIQLT TAEGETMAMT GEAQSYQEKS LTQIAPESPK LNQLNPRYTF
     SRFVVGPTNR MAHAASLAVA ESPGREFNPL FLCGGVGLGK THLMQAIAHY RLELYPNAKV
     FYVSTEQFTN DLIAAIRQDS MERFREHYRR ADFLLIDDIQ FIEGKEYTQE ELFHTFNTLH
     EAGKQVVLAS DRAPKRIPTL QDRLISRFSM GLIADIQVPD LETRMAILQK KAQYENMRLP
     RDVVEYIATN YTSNIRELEG ALIRAIAYTS ISGLSMTVQN IAPVLNPPVE QVPASPEVIL
     RTVAESLKVS IEDLKGSSRR REISFARQVG MYLMRQHTEL SLPRIGEEFG GKDHTTVLYS
     CDKISKLQQK DWELSQMLSE LSDRINMASR TQS
//
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