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Database: UniProt
Entry: DNAA_DEIDV
LinkDB: DNAA_DEIDV
Original site: DNAA_DEIDV 
ID   DNAA_DEIDV              Reviewed;         456 AA.
AC   C1CXJ1;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   21-SEP-2011, sequence version 2.
DT   07-JUN-2017, entry version 52.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000255|HAMAP-Rule:MF_00377};
GN   Name=dnaA {ECO:0000255|HAMAP-Rule:MF_00377};
GN   OrderedLocusNames=Deide_00010;
OS   Deinococcus deserti (strain VCD115 / DSM 17065 / LMG 22923).
OC   Bacteria; Deinococcus-Thermus; Deinococci; Deinococcales;
OC   Deinococcaceae; Deinococcus.
OX   NCBI_TaxID=546414;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VCD115 / DSM 17065 / LMG 22923;
RX   PubMed=19370165; DOI=10.1371/journal.pgen.1000434;
RA   de Groot A., Dulermo R., Ortet P., Blanchard L., Guerin P.,
RA   Fernandez B., Vacherie B., Dossat C., Jolivet E., Siguier P.,
RA   Chandler M., Barakat M., Dedieu A., Barbe V., Heulin T., Sommer S.,
RA   Achouak W., Armengaud J.;
RT   "Alliance of proteomics and genomics to unravel the specificities of
RT   Sahara bacterium Deinococcus deserti.";
RL   PLoS Genet. 5:E1000434-E1000434(2009).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000255|HAMAP-
CC       Rule:MF_00377}.
DR   EMBL; CP001114; ACO44797.2; -; Genomic_DNA.
DR   RefSeq; WP_012691920.1; NC_012526.1.
DR   SMR; C1CXJ1; -.
DR   STRING; 546414.Deide_00010; -.
DR   PaxDb; C1CXJ1; -.
DR   EnsemblBacteria; ACO44797; ACO44797; Deide_00010.
DR   KEGG; ddr:Deide_00010; -.
DR   eggNOG; ENOG4105CI4; Bacteria.
DR   eggNOG; COG0593; LUCA.
DR   HOGENOM; HOG000235658; -.
DR   KO; K02313; -.
DR   OrthoDB; POG091H02FF; -.
DR   Proteomes; UP000002208; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:InterPro.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA replication;
KW   DNA-binding; Nucleotide-binding; Reference proteome.
FT   CHAIN         1    456       Chromosomal replication initiator protein
FT                                DnaA.
FT                                /FTId=PRO_1000205649.
FT   NP_BIND     154    161       ATP. {ECO:0000255|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   456 AA;  51482 MW;  E50F45A06AEA464B CRC64;
     MSQEIWADVL GYVRKNISEV EYHTWFAPLK NLGVQDGSLV LGVRNSFAQE WLRKQYQGLL
     EDALRSLGAQ HPQVSFQVLP ASQDALLLPS DPPPAPISPG RAPAPPPADN RKTLNPKYTF
     ENFVVGPNNN LAHAAALAVA ESPGKAYNPL FIYGDVGLGK THLMHAVGHY IAERFPEKRI
     EYVSTETFTN ELINAIREDK TTQFRNRYRS VDLLLVDDIQ FLAGKERTQE EFFHTFNALY
     ENHKQIILSS DRPPKDIQTL EGRLRSRFEW GLITDIQSPE FETRVAILKM NAEHNRIDIP
     QEVLELIARQ VTTNIRELEG ALMRVVAFSS LNNVPFSRAV ASKALSNVFA PQEVKVEMMD
     VLRQVASHFN MPPDVIRGSG RVREVVVPRQ VAQYLIRDLT DHSLPEIGQF FGRDHSTVMH
     AISKVTEQLG KDSELTAAVE TLRRKMKGLE DEDSRA
//
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