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Database: UniProt
Entry: DNAA_DESVM
LinkDB: DNAA_DESVM
Original site: DNAA_DESVM 
ID   DNAA_DESVM              Reviewed;         498 AA.
AC   B8DN19;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   03-MAR-2009, sequence version 1.
DT   07-JUN-2017, entry version 56.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000255|HAMAP-Rule:MF_00377};
GN   Name=dnaA {ECO:0000255|HAMAP-Rule:MF_00377};
GN   OrderedLocusNames=DvMF_0001;
OS   Desulfovibrio vulgaris (strain Miyazaki F / DSM 19637).
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Desulfovibrionales;
OC   Desulfovibrionaceae; Desulfovibrio.
OX   NCBI_TaxID=883;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Miyazaki F / DSM 19637;
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E.,
RA   Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Brettin T.,
RA   Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N.,
RA   Mikhailova N., Hazen T.C., Richardson P.;
RT   "Complete sequence of Desulfovibrio vulgaris str. 'Miyazaki F'.";
RL   Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000255|HAMAP-
CC       Rule:MF_00377}.
DR   EMBL; CP001197; ACL06963.1; -; Genomic_DNA.
DR   RefSeq; WP_012611171.1; NC_011769.1.
DR   ProteinModelPortal; B8DN19; -.
DR   SMR; B8DN19; -.
DR   STRING; 883.DvMF_0001; -.
DR   EnsemblBacteria; ACL06963; ACL06963; DvMF_0001.
DR   KEGG; dvm:DvMF_0001; -.
DR   eggNOG; ENOG4105CI4; Bacteria.
DR   eggNOG; COG0593; LUCA.
DR   HOGENOM; HOG000235659; -.
DR   KO; K02313; -.
DR   OMA; REFNPLF; -.
DR   OrthoDB; POG091H02FF; -.
DR   Proteomes; UP000001361; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:InterPro.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA replication;
KW   DNA-binding; Nucleotide-binding; Reference proteome.
FT   CHAIN         1    498       Chromosomal replication initiator protein
FT                                DnaA.
FT                                /FTId=PRO_1000121972.
FT   NP_BIND     196    203       ATP. {ECO:0000255|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   498 AA;  54697 MW;  DC8C550B16DFD858 CRC64;
     MISIWGQIQN ILEKSLNPGL FKVWISPLAA EVQDDVLRLV APNEFVAAWV RDRLLDDIVQ
     AATTVLGSAP TVVVDAAPQG AGSLSPRMGR AGASASAAVP GANAADGTQP VPAVQISSAV
     QAVAARSASG VGARAAHVAQ PSQLGLPLDM PAPNRALNWR FSFDSFVVGP NNELAFAASR
     GICRETLSAD TLFLSSGPGL GKTHLMQAVG RALCEASNRA APRVEYLTAE EFATRLIAAL
     KAREVDRFKA RYRDVDVLLL EDVHFLQGKE RMQDEVLATV KALKSRGSRV VLSSSFAARD
     LKNLDTQLVS RFCSGFLAHI DKPGFETRRR ILCEKARLHQ VMLPDNVTDL LADRIRTDVR
     QIESCLHNLV LKAKLLNRQI SMEMAWEVLG HYAQQEVVMD FEGIVRKVCE GFGISPKQLN
     SRSRKREYVV ARNSVFYLAR KHTDLSLKEI GDRFSRRHST VLKGITSIER EMSRETPLGR
     QVTNTLSLIE RNGRITYP
//
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