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Database: UniProt
Entry: DNAA_FLAPJ
LinkDB: DNAA_FLAPJ
Original site: DNAA_FLAPJ 
ID   DNAA_FLAPJ              Reviewed;         478 AA.
AC   A6GYW8;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-JUL-2007, sequence version 1.
DT   25-OCT-2017, entry version 62.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000255|HAMAP-Rule:MF_00377};
GN   Name=dnaA {ECO:0000255|HAMAP-Rule:MF_00377}; OrderedLocusNames=FP1208;
OS   Flavobacterium psychrophilum (strain JIP02/86 / ATCC 49511).
OC   Bacteria; Bacteroidetes; Flavobacteriia; Flavobacteriales;
OC   Flavobacteriaceae; Flavobacterium.
OX   NCBI_TaxID=402612;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JIP02/86 / ATCC 49511;
RX   PubMed=17592475; DOI=10.1038/nbt1313;
RA   Duchaud E., Boussaha M., Loux V., Bernardet J.-F., Michel C.,
RA   Kerouault B., Mondot S., Nicolas P., Bossy R., Caron C., Bessieres P.,
RA   Gibrat J.-F., Claverol S., Dumetz F., Le Henaff M., Benmansour A.;
RT   "Complete genome sequence of the fish pathogen Flavobacterium
RT   psychrophilum.";
RL   Nat. Biotechnol. 25:763-769(2007).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000255|HAMAP-
CC       Rule:MF_00377}.
DR   EMBL; AM398681; CAL43291.1; -; Genomic_DNA.
DR   RefSeq; WP_011963340.1; NC_009613.3.
DR   RefSeq; YP_001296102.1; NC_009613.3.
DR   ProteinModelPortal; A6GYW8; -.
DR   SMR; A6GYW8; -.
DR   STRING; 402612.FP1208; -.
DR   EnsemblBacteria; CAL43291; CAL43291; FP1208.
DR   GeneID; 5299442; -.
DR   KEGG; fps:FP1208; -.
DR   PATRIC; fig|402612.5.peg.1222; -.
DR   eggNOG; ENOG4105CI4; Bacteria.
DR   eggNOG; COG0593; LUCA.
DR   HOGENOM; HOG000235658; -.
DR   KO; K02313; -.
DR   OMA; REFNPLF; -.
DR   OrthoDB; POG091H02FF; -.
DR   Proteomes; UP000006394; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:InterPro.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA replication;
KW   DNA-binding; Nucleotide-binding; Reference proteome.
FT   CHAIN         1    478       Chromosomal replication initiator protein
FT                                DnaA.
FT                                /FTId=PRO_1000048644.
FT   NP_BIND     183    190       ATP. {ECO:0000255|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   478 AA;  55019 MW;  D65E0701D5CE51F8 CRC64;
     MHTMNKTAES VWDNCLSFIK DNIQEQAYKT WFEPIKSVEL TDNALYIQVP SKFFYEWLEE
     HYVKLLKVAL TKELGKNAKL LYKIKMENTY GNKLPFTEQL PSAHRSPVRT QEIDVPVQQK
     NPELRNPFII PGIRNLKIES QLNANYSFDN FLEGDSNRLA RSAGMAVANK PGGTSFNPLL
     IFGGVGLGKT HLAHAIGVEV KEKYPEKTVL YISAEIFTQQ YIESVKKNNR NDFIHFYQLI
     DVLIIDDVQF LSGKTGTQDV FFHIFNYLHQ NGKQVILTSD KAPVDMQDIE QRLLSRFKWG
     LSAEIHQPDY ETRISILKNI LYRDGVEMPE EIIEYVARNI KSNVRELEGA IISLIAQSSF
     NKKEVTLELA KQVVEKFVKN VKREVSIDYI QKVVSDYFQL DLEVLQSKTR KRHVVQARQL
     AMFFAKRYTK ASLANIGSQI GDRDHATVLH ACKTVDNLVT TDKQFKKFVD DINKKLSL
//
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